APC/Fire™ 750 anti-human CD11a | BioLegend 301226 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC/Fire™ 750 anti-human CD11a

catalog :

301226

quantity :

100 tests

price :

292 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

HI111

The same clone is also sold as:

Abnova: MAB13792, MAB13795, MAB13794, MAB13793, MAB13791
Invitrogen: 16-0119-050, 16-0119-025, 14-0119-80, 11-0119-42, 11-0119-41, 16-0119-81, 14-0119-82
Abcam: ab185767
Santa Cruz Biotechnology: sc-19647
BD Biosciences: 550852, 555383, 559875, 555384, 555381, 555382

reactivity :

human, dogs, bovine, chimpanzee

application :

flow cytometry

citations: 4

Reference
Sinclair L, Barthelemy C, Cantrell D. Single Cell Glucose Uptake Assays: A Cautionary Tale. Immunometabolism. 2020;2:e200029 pubmed publisher
Chew H, De Lima P, Gonzalez Cruz J, Banushi B, Echejoh G, Hu L, et al. Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies. Cell. 2020;180:895-914.e27 pubmed publisher
Daglas M, Draxler D, Ho H, McCutcheon F, Galle A, Au A, et al. Activated CD8+ T Cells Cause Long-Term Neurological Impairment after Traumatic Brain Injury in Mice. Cell Rep. 2019;29:1178-1191.e6 pubmed publisher
Choi E, Orlova V, Fagerholm S, Nurmi S, Zhang L, Ballantyne C, et al. Regulation of LFA-1-dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins. Blood. 2008;111:3607-14 pubmed publisher

product information

Antigen :

CD11a

Apps. Abbrev. :

Flow Cytometry

Cat # :

301226

Clone :

HI111

Item :

APC/Fire™ 750 anti-human CD11a

Isotype :

Mouse IgG1, κ

Other Names :

LFA-1α chain, Integrin αL subunit, αL Integrin, ITGAL

Size :

100 tests

Price (USD) :

292 USD

Reactivity :

Human, African Green, Baboon, Cattle (Bovine, Cow), Capuchin monkey, Chimpanzee, Cynomolgus, Dog (Canine), Horse (Equine), Rabbit (Lapine), Sheep (Ovine)

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC_F750

Application Notes :

Clone HI111 epitope maps to the top region of the I domain that is close to the putative ligand-binding site surrounding the MIDAS (metal ion-dependent adhesion site). HI111 is specific for the closed confirmation of the integrin 8 . Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections, Western blotting 2 , and blocking of cell-cell interaction and inhibition the binding of ICAM-1 4 . This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 301233 301234).