Alexa Fluor® 594 anti-human CD11a | BioLegend 301222 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Alexa Fluor® 594 anti-human CD11a

catalog :

301222

quantity :

100 μg

price :

248 USD

clonality :

monoclonal

host :

mouse

conjugate :

Alexa Fluor 594

clone name :

HI111

reactivity :

human, dogs, bovine, chimpanzee

application :

immunocytochemistry, flow cytometry

more info or order :

BioLegend product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig s1	Matsumoto K, Kurasawa T, Yoshimoto K, Suzuki K, Takeuchi T. Identification of neutrophil β2-integrin LFA-1 as a potential mechanistic biomarker in ANCA-associated vasculitis via microarray and validation analyses. Arthritis Res Ther. 2021;23:136 pubmed publisher
flow cytometry; dogs; loading ...; fig 4c	McGill J, Wang Y, Ganta C, Boorgula G, Ganta R. Antigen-Specific CD4+CD8+ Double-Positive T Cells Are Increased in the Blood and Spleen During Ehrlichia chaffeensis Infection in the Canine Host. Front Immunol. 2018;9:1585 pubmed publisher
	Kastelberg B, Tubau Juni N, Ayubi T, Leung A, Leber A, Hontecillas R, et al. NLRX1 is a key regulator of immune signaling during invasive pulmonary aspergillosis. PLoS Pathog. 2020;16:e1008854 pubmed publisher
	Ristow L, Tran V, Schwartz K, Pankratz L, Mehle A, Sauer J, et al. The Extracellular Domain of the β2 Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity. MBio. 2019;10: pubmed publisher
	Bouafia A, Lofek S, Bruneau J, Chentout L, Lamrini H, Trinquand A, et al. Loss of ARHGEF1 causes a human primary antibody deficiency. J Clin Invest. 2019;129:1047-1060 pubmed publisher
	Stoeckius M, Zheng S, Houck Loomis B, Hao S, Yeung B, Mauck W, et al. Cell Hashing with barcoded antibodies enables multiplexing and doublet detection for single cell genomics. Genome Biol. 2018;19:224 pubmed publisher
	Li N, Yang H, Wang M, Lü S, Zhang Y, Long M. Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling. Mol Biol Cell. 2018;29:408-418 pubmed publisher
	Vargas Hernandez A, Mace E, Zimmerman O, Zerbe C, Freeman A, Rosenzweig S, et al. Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations. J Allergy Clin Immunol. 2018;141:2142-2155.e5 pubmed publisher
	Resheq Y, Menzner A, Bosch J, Tickle J, Li K, Wilhelm A, et al. Impaired Transmigration of Myeloid-Derived Suppressor Cells across Human Sinusoidal Endothelium Is Associated with Decreased Expression of CD13. J Immunol. 2017;199:1672-1681 pubmed publisher
	Papa I, Saliba D, Ponzoni M, Bustamante S, Canete P, Gonzalez Figueroa P, et al. TFH-derived dopamine accelerates productive synapses in germinal centres. Nature. 2017;547:318-323 pubmed publisher
	Johnson D, Wayt J, Wilson J, Donaldson J. Arf6 and Rab22 mediate T cell conjugate formation by regulating clathrin-independent endosomal membrane trafficking. J Cell Sci. 2017;130:2405-2415 pubmed publisher
	Kyei S, Ogbomo H, Li S, Timm McCann M, Xiang R, Huston S, et al. Mechanisms by Which Interleukin-12 Corrects Defective NK Cell Anticryptococcal Activity in HIV-Infected Patients. MBio. 2016;7: pubmed publisher
	Choi E, Orlova V, Fagerholm S, Nurmi S, Zhang L, Ballantyne C, et al. Regulation of LFA-1-dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins. Blood. 2008;111:3607-14 pubmed publisher

product information

Antigen :

CD11a

Apps. Abbrev. :

ICC, Flow Cytometry

Cat # :

301222

Clone :

HI111

Item :

Alexa Fluor® 594 anti-human CD11a

Isotype :

Mouse IgG1, κ

Other Names :

LFA-1α chain, Integrin αL subunit, αL Integrin, ITGAL

Size :

100 μg

Price (USD) :

248 USD

Reactivity :

Human, African Green, Baboon, Cattle (Bovine, Cow), Capuchin monkey, Chimpanzee, Cynomolgus, Dog (Canine), Horse (Equine), Rabbit (Lapine), Sheep (Ovine)

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

A594

Application Notes :

Clone HI111 epitope maps to the top region of the I domain that is close to the putative ligand-binding site surrounding the MIDAS (metal ion-dependent adhesion site). HI111 is specific for the closed confirmation of the integrin 8 . Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections, Western blotting 2 , and blocking of cell-cell interaction and inhibition the binding of ICAM-1 4 . This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 301233 301234).

more info or order :

BioLegend product webpage