PE/Cyanine7 anti-human CD11a | BioLegend 301220 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE/Cyanine7 anti-human CD11a

catalog :

301220

quantity :

100 tests

price :

293 USD

clonality :

monoclonal

host :

mouse

conjugate :

PE/Cy7

clone name :

HI111

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig s1	Matsumoto K, Kurasawa T, Yoshimoto K, Suzuki K, Takeuchi T. Identification of neutrophil β2-integrin LFA-1 as a potential mechanistic biomarker in ANCA-associated vasculitis via microarray and validation analyses. Arthritis Res Ther. 2021;23:136 pubmed publisher
flow cytometry; human; loading ...; fig 5a	Warthan M, Washington S, Franzese S, Ramus R, Kim K, York T, et al. The role of endoplasmic reticulum aminopeptidase 2 in modulating immune detection of choriocarcinoma. Biol Reprod. 2018;98:309-322 pubmed publisher
	Baranek T, Lebrigand K, de Amat Herbozo C, Gonzalez L, Bogard G, Dietrich C, et al. High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision. Cell Rep. 2020;32:108116 pubmed publisher
	Kaya B, Doñas C, Wuggenig P, Diaz O, Morales R, Melhem H, et al. Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1+ Macrophages Regulates Intestinal Homeostasis. Cell Rep. 2020;32:107979 pubmed publisher
	Seamon K, Kurlak L, Warthan M, Stratikos E, Strauss J, Mistry H, et al. The Differential Expression of ERAP1/ERAP2 and Immune Cell Activation in Pre-eclampsia. Front Immunol. 2020;11:396 pubmed publisher
	Elsner R, Shlomchik M. IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression. Cell Rep. 2019;29:2796-2809.e5 pubmed publisher
	Ly A, Liao Y, Pietrzak H, Ioannidis L, Sidwell T, Gloury R, et al. Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria. Cell Rep. 2019;29:2257-2269.e6 pubmed publisher
	Choi E, Orlova V, Fagerholm S, Nurmi S, Zhang L, Ballantyne C, et al. Regulation of LFA-1-dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins. Blood. 2008;111:3607-14 pubmed publisher

product information

Antigen :

CD11a

Apps. Abbrev. :

Cat # :

301220

Clone :

HI111

Item :

PE/Cyanine7 anti-human CD11a

Isotype :

Mouse IgG1, κ

Other Names :

LFA-1α chain, Integrin αL subunit, αL Integrin, ITGAL

Size :

100 tests

Price (USD) :

293 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PE_CYANINE7

Application Notes :

Clone HI111 epitope maps to the top region of the I domain that is close to the putative ligand-binding site surrounding the MIDAS (metal ion-dependent adhesion site). HI111 is specific for the closed confirmation of the integrin^8. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections, Western blotting^2, and blocking of cell-cell interaction and inhibition the binding of ICAM-1^4. This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 301233 & 301234).;

more info or order :

BioLegend product webpage