APC anti-human CD11a | BioLegend 301212 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-human CD11a

catalog :

301212

quantity :

100 tests

price :

292 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

HI111

The same clone is also sold as:

Abnova: MAB13795, MAB13792, MAB13791, MAB13793, MAB13794
Abcam: ab185767
Santa Cruz Biotechnology: sc-19647
Invitrogen: 11-0119-42, 16-0119-050, 14-0119-82, 11-0119-41, 14-0119-80, 16-0119-81, 16-0119-025
BD Biosciences: 559875, 555381, 550852, 555383, 555384, 555382

reactivity :

human, dogs, bovine, chimpanzee

application :

flow cytometry

citations: 6

Reference
Beatson R, Parente Pereira A, Halim L, Cozzetto D, Hull C, Whilding L, et al. TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer. Cell Rep Med. 2021;2:100473 pubmed publisher
Leylek R, Alcántara Hernández M, Granja J, Chavez M, Perez K, Diaz O, et al. Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity. Cell Rep. 2020;32:108180 pubmed publisher
Vera Aguilera J, Paludo J, McWilliams R, Zhang H, Li Y, Kumar A, et al. Chemo-immunotherapy combination after PD-1 inhibitor failure improves clinical outcomes in metastatic melanoma patients. Melanoma Res. 2020;30:364-375 pubmed publisher
Michlmayr D, Kim E, Rahman A, Raghunathan R, Kim Schulze S, Che Y, et al. Comprehensive Immunoprofiling of Pediatric Zika Reveals Key Role for Monocytes in the Acute Phase and No Effect of Prior Dengue Virus Infection. Cell Rep. 2020;31:107569 pubmed publisher
Waugh K, Araya P, Pandey A, Jordan K, Smith K, Granrath R, et al. Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome. Cell Rep. 2019;29:1893-1908.e4 pubmed publisher
Yan Y, Cao S, Liu X, Harrington S, Bindeman W, Adjei A, et al. CX3CR1 identifies PD-1 therapy-responsive CD8+ T cells that withstand chemotherapy during cancer chemoimmunotherapy. JCI Insight. 2018;3: pubmed publisher

product information

Antigen :

CD11a

Apps. Abbrev. :

Flow Cytometry

Cat # :

301212

Clone :

HI111

Item :

APC anti-human CD11a

Isotype :

Mouse IgG1, κ

Other Names :

LFA-1α chain, Integrin αL subunit, αL Integrin, ITGAL

Size :

100 tests

Price (USD) :

292 USD

Reactivity :

Human, African Green, Baboon, Cattle (Bovine, Cow), Capuchin monkey, Chimpanzee, Cynomolgus, Dog (Canine), Horse (Equine), Rabbit (Lapine), Sheep (Ovine)

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC

Application Notes :

Clone HI111 epitope maps to the top region of the I domain that is close to the putative ligand-binding site surrounding the MIDAS (metal ion-dependent adhesion site). HI111 is specific for the closed confirmation of the integrin 8 . Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections, Western blotting 2 , and blocking of cell-cell interaction and inhibition the binding of ICAM-1 4 . This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 301233 301234).