FITC anti-human CD11a | BioLegend 301206 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

FITC anti-human CD11a

catalog :

301206

quantity :

100 tests

price :

191 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

HI111

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 1a	Buffone A, Anderson N, Hammer D. Migration against the direction of flow is LFA-1-dependent in human hematopoietic stem and progenitor cells. J Cell Sci. 2018;131: pubmed publisher
flow cytometry; human; loading ...; fig 2	Krogh Nielsen M, Hector S, Allen K, Subhi Y, Sørensen T. Altered activation state of circulating neutrophils in patients with neovascular age-related macular degeneration. Immun Ageing. 2017;14:18 pubmed publisher
flow cytometry; human; fig 5	Difranco K, Johnson Farley N, Bertino J, Elson D, Vega B, Belinka B, et al. LFA-1-targeting Leukotoxin (LtxA; LeukotheraÂ®) causes lymphoma tumor regression in a humanized mouse model and requires caspase-8 and Fas to kill malignant lymphocytes. Leuk Res. 2015;39:649-56 pubmed publisher
	Leylek R, Alcántara Hernández M, Granja J, Chavez M, Perez K, Diaz O, et al. Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity. Cell Rep. 2020;32:108180 pubmed publisher
	Michlmayr D, Kim E, Rahman A, Raghunathan R, Kim Schulze S, Che Y, et al. Comprehensive Immunoprofiling of Pediatric Zika Reveals Key Role for Monocytes in the Acute Phase and No Effect of Prior Dengue Virus Infection. Cell Rep. 2020;31:107569 pubmed publisher
	Waugh K, Araya P, Pandey A, Jordan K, Smith K, Granrath R, et al. Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome. Cell Rep. 2019;29:1893-1908.e4 pubmed publisher
	Mahajan A, Grüneboom A, Petru L, Podolska M, Kling L, Maueröder C, et al. Frontline Science: Aggregated neutrophil extracellular traps prevent inflammation on the neutrophil-rich ocular surface. J Leukoc Biol. 2019;105:1087-1098 pubmed publisher
	Bouafia A, Lofek S, Bruneau J, Chentout L, Lamrini H, Trinquand A, et al. Loss of ARHGEF1 causes a human primary antibody deficiency. J Clin Invest. 2019;129:1047-1060 pubmed publisher
	Kamel A, El Sharkawy N, Osman R, Abd El Fattah E, El Noshokaty E, Abd El Hamid T, et al. Adhesion molecules expression in CLL: Potential impact on clinical and hematological parameters. J Egypt Natl Canc Inst. 2016;28:31-7 pubmed publisher
	Choi E, Orlova V, Fagerholm S, Nurmi S, Zhang L, Ballantyne C, et al. Regulation of LFA-1-dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins. Blood. 2008;111:3607-14 pubmed publisher

product information

Antigen :

CD11a

Apps. Abbrev. :

Cat # :

301206

Clone :

HI111

Item :

FITC anti-human CD11a

Isotype :

Mouse IgG1, κ

Other Names :

LFA-1α chain, Integrin αL subunit, αL Integrin, ITGAL

Size :

100 tests

Price (USD) :

191 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

FITC

Application Notes :

Clone HI111 epitope maps to the top region of the I domain that is close to the putative ligand-binding site surrounding the MIDAS (metal ion-dependent adhesion site). HI111 is specific for the closed confirmation of the integrin^8. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections, Western blotting^2, and blocking of cell-cell interaction and inhibition the binding of ICAM-1^4. This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 301233 & 301234).;

more info or order :

BioLegend product webpage