APC/Cyanine7 anti-human CD8a | BioLegend 301015 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC/Cyanine7 anti-human CD8a

catalog :

301015

quantity :

25 tests

price :

130 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC/Cy7

clone name :

RPA-T8

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
	Leylek R, Alcántara Hernández M, Lanzar Z, Lüdtke A, Perez O, Reizis B, et al. Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population. Cell Rep. 2019;29:3736-3750.e8 pubmed publisher
	Usmani S, Murooka T, Deruaz M, Koh W, Sharaf R, Di Pilato M, et al. HIV-1 Balances the Fitness Costs and Benefits of Disrupting the Host Cell Actin Cytoskeleton Early after Mucosal Transmission. Cell Host Microbe. 2019;25:73-86.e5 pubmed publisher
	Yuan Z, Kang G, Daharsh L, Fan W, Li Q. SIVcpz closely related to the ancestral HIV-1 is less or non-pathogenic to humans in a hu-BLT mouse model. Emerg Microbes Infect. 2018;7:59 pubmed publisher
	Alcántara Hernández M, Leylek R, Wagar L, Engleman E, Keler T, Marinkovich M, et al. High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization. Immunity. 2017;47:1037-1050.e6 pubmed publisher
	Yuan Z, Kang G, Ma F, Lu W, Fan W, Fennessey C, et al. Recapitulating Cross-Species Transmission of Simian Immunodeficiency Virus SIVcpz to Humans by Using Humanized BLT Mice. J Virol. 2016;90:7728-39 pubmed publisher
	Chiu Y, Lin C, Sung B, Chuang Y, Schneck J, Kern F, et al. Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size. Sci Rep. 2016;6:19227 pubmed publisher
	Tew G, Hackney J, Gibbons D, Lamb C, Luca D, Egen J, et al. Association Between Response to Etrolizumab and Expression of Integrin Î±E and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis. Gastroenterology. 2016;150:477-87.e9 pubmed publisher
	Spencer A, Cottingham M, Jenks J, Longley R, Capone S, Colloca S, et al. Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class ii invariant chain. PLoS ONE. 2014;9:e100538 pubmed publisher
	Xue J, Cong Z, Xiong J, Wang W, Jiang H, Chen T, et al. Repressive effect of primary virus replication on superinfection correlated with gut-derived central memory CD4(+) T cells in SHIV-infected Chinese rhesus macaques. PLoS ONE. 2013;8:e72295 pubmed publisher
	Weinfurter J, Brunner K, Capuano S, Li C, Broman K, Kawaoka Y, et al. Cross-reactive T cells are involved in rapid clearance of 2009 pandemic H1N1 influenza virus in nonhuman primates. PLoS Pathog. 2011;7:e1002381 pubmed publisher

product information

Antigen :

CD8a

Apps. Abbrev. :

Flow Cytometry

Cat # :

301015

Clone :

RPA-T8

Item :

APC/Cyanine7 anti-human CD8a

Isotype :

Mouse IgG1, κ

Other Names :

T8, Leu2

Size :

25 tests

Price (USD) :

130 USD

Reactivity :

Human, Cross-Reactivity: Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque, Sooty Mangabey

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC_CYANINE7

Application Notes :

The RPA-T8 antibody does not block the binding of HIT8a antibody to CD8a. Additional reported applications of this antibody (for the relevant formats) include: immunohistochemical staining of paraformaldehyde-fixed frozen sections 3 and costimulation of T cell responses 4 . This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. The Ultra-LEAF™ purified antibody (Endotoxin 0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. Nos. 301073 301074).

more info or order :

BioLegend product webpage