PE/Cyanine7 anti-human CD8a | BioLegend 301012 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE/Cyanine7 anti-human CD8a

catalog :

301012

quantity :

100 tests

price :

292 USD

clonality :

monoclonal

host :

mouse

conjugate :

PE/Cy7

clone name :

RPA-T8

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; tbl s9	Mordmuller B, Surat G, Lagler H, Chakravarty S, Ishizuka A, Lalremruata A, et al. Sterile protection against human malaria by chemoattenuated PfSPZ vaccine. Nature. 2017;542:445-449 pubmed publisher
flow cytometry; human	Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
	Toor S, Sasidharan Nair V, Murshed K, Abu Nada M, Elkord E. Tumor-Infiltrating Lymphoid Cells in Colorectal Cancer Patients with Varying Disease Stages and Microsatellite Instability-High/Stable Tumors. Vaccines (Basel). 2021;9: pubmed publisher
	Carpenter R, Jiang R, Brennan F, Hall J, Gottipati M, Niewiesk S, et al. Human immune cells infiltrate the spinal cord and impair recovery after spinal cord injury in humanized mice. Sci Rep. 2019;9:19105 pubmed publisher
	Mastelic Gavillet B, Navarro Rodrigo B, Décombaz L, Wang H, Ercolano G, Ahmed R, et al. Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8+ T cells. J Immunother Cancer. 2019;7:257 pubmed publisher
	Burbano Y, Paz A, Caldon C, Constain J, Gonzáles G, Hernández J, et al. Low Frequency Of Regulatory B-Cells And Increased CD4+ and CD8+ Interferon-γ-producing cells in patients with tropical spastic paraparesis associated with human T-cell lymphotropic virus type. Rev Soc Bras Med Trop. 2019;52:e20190101 pubmed publisher
	Alhaj Hussen K, Vu Manh T, Guimiot F, Nelson E, Chabaane E, Delord M, et al. Molecular and Functional Characterization of Lymphoid Progenitor Subsets Reveals a Bipartite Architecture of Human Lymphopoiesis. Immunity. 2017;47:680-696.e8 pubmed publisher
	Barbarin A, Cayssials E, Jacomet F, Núñez N, Basbous S, Lefèvre L, et al. Phenotype of NK-Like CD8(+) T Cells with Innate Features in Humans and Their Relevance in Cancer Diseases. Front Immunol. 2017;8:316 pubmed publisher
	Khaitan A, Kilberg M, Kravietz A, Ilmet T, Tastan C, Mwamzuka M, et al. HIV-Infected Children Have Lower Frequencies of CD8+ Mucosal-Associated Invariant T (MAIT) Cells that Correlate with Innate, Th17 and Th22 Cell Subsets. PLoS ONE. 2016;11:e0161786 pubmed publisher
	Karlsson H, Svensson E, Gigg C, Jarvius M, Olsson StrÃ¶mberg U, Savoldo B, et al. Evaluation of Intracellular Signaling Downstream Chimeric Antigen Receptors. PLoS ONE. 2015;10:e0144787 pubmed publisher
	Pasetto A, Frelin L, Brass A, Yasmeen A, Koh S, Lohmann V, et al. Generation of T-cell receptors targeting a genetically stable and immunodominant cytotoxic T-lymphocyte epitope within hepatitis C virus non-structural protein 3. J Gen Virol. 2012;93:247-58 pubmed publisher

product information

Antigen :

CD8a

Apps. Abbrev. :

Flow Cytometry

Cat # :

301012

Clone :

RPA-T8

Item :

PE/Cyanine7 anti-human CD8a

Isotype :

Mouse IgG1, κ

Other Names :

T8, Leu2

Size :

100 tests

Price (USD) :

292 USD

Reactivity :

Human, Cross-Reactivity: Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque, Sooty Mangabey

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PE_CYANINE7

Application Notes :

The RPA-T8 antibody does not block the binding of HIT8a antibody to CD8a. Additional reported applications of this antibody (for the relevant formats) include: immunohistochemical staining of paraformaldehyde-fixed frozen sections 3 and costimulation of T cell responses 4 . This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. The Ultra-LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. Nos. 301073 301074).

more info or order :

BioLegend product webpage