APC/Cyanine7 anti-human CD8a | BioLegend 300925 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC/Cyanine7 anti-human CD8a

catalog :

300925

quantity :

25 tests

price :

143 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC/Cy7

clone name :

Hit8a

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 17

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:40	Gibbons D, Fleming P, Virasami A, Michel M, Sebire N, Costeloe K, et al. Interleukin-8 (CXCL8) production is a signatory T cell effector function of human newborn infants. Nat Med. 2014;20:1206-10 pubmed publisher
	Grant R, Coopman K, Silva Gomes S, Campbell J, Kara B, Braybrook J, et al. Assessment of Protocol Impact on Subjectivity Uncertainty When Analyzing Peripheral Blood Mononuclear Cell Flow Cytometry Data Files. Methods Protoc. 2021;4: pubmed publisher
	Delacher M, Simon M, Sanderink L, Hotz Wagenblatt A, Wuttke M, Schambeck K, et al. Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells. Immunity. 2021;54:702-720.e17 pubmed publisher
	Fang Y, Wang L, Wan C, Sun Y, Van der Jeught K, Zhou Z, et al. MAL2 drives immune evasion in breast cancer by suppressing tumor antigen presentation. J Clin Invest. 2021;131: pubmed publisher
	Zavidij O, Haradhvala N, Mouhieddine T, Sklavenitis Pistofidis R, Cai S, Reidy M, et al. Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma. Nat Cancer. 2020;1:493-506 pubmed publisher
	Corrado M, Edwards Hicks J, Villa M, Flachsmann L, Sanin D, Jacobs M, et al. Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity. Cell Metab. 2020;32:981-995.e7 pubmed publisher
	Islas Vazquez L, Aguilar Cazares D, Galicia Velasco M, Rumbo Nava U, Meneses Flores M, Luna Rivero C, et al. IL-6, NLR, and SII Markers and Their Relation with Alterations in CD8+ T-Lymphocyte Subpopulations in Patients Treated for Lung Adenocarcinoma. Biology (Basel). 2020;9: pubmed publisher
	Lin R, Zhang Y, Pradhan K, Li L. TICAM2-related pathway mediates neutrophil exhaustion. Sci Rep. 2020;10:14397 pubmed publisher
	Khan K, Ponce de León J, Benguigui M, Xu P, Chow A, Cruz Munoz W, et al. Immunostimulatory and anti-tumor metronomic cyclophosphamide regimens assessed in primary orthotopic and metastatic murine breast cancer. NPJ Breast Cancer. 2020;6:29 pubmed publisher
	Zhang C, Yue C, Herrmann A, Song J, Egelston C, Wang T, et al. STAT3 Activation-Induced Fatty Acid Oxidation in CD8+ T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth. Cell Metab. 2020;31:148-161.e5 pubmed publisher
	Hu Q, Sun W, Wang J, Ruan H, Zhang X, Ye Y, et al. Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy. Nat Biomed Eng. 2018;2:831-840 pubmed publisher
	Corleis B, Bucşan A, Deruaz M, Vrbanac V, Lisanti Park A, Gates S, et al. HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis. Cell Rep. 2019;26:1409-1418.e5 pubmed publisher
	Lee H, Kim Y, Sim C, Heo S, Song I, Park H, et al. Expansion of tumor-infiltrating lymphocytes and their potential for application as adoptive cell transfer therapy in human breast cancer. Oncotarget. 2017;8:113345-113359 pubmed publisher
	Chen J, Chernatynskaya A, Li J, Kimbrell M, Cassidy R, Perry D, et al. T cells display mitochondria hyperpolarization in human type 1 diabetes. Sci Rep. 2017;7:10835 pubmed publisher
	Burke M, Sambira Nahum L, Isbel N, Carroll R, Soyer H, Francis R, et al. Sirolimus Increases T-Cell Abundance in the Sun Exposed Skin of Kidney Transplant Recipients. Transplant Direct. 2017;3:e171 pubmed publisher
	Freeman A, Bridge J, Maruthayanar P, Overgaard N, Jung J, Simpson F, et al. Comparative immune phenotypic analysis of cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in immune-competent individuals: proportional representation of CD8+ T-cells but not FoxP3+ Regulatory T-cells is associated with disease stage. PLoS ONE. 2014;9:e110928 pubmed publisher
	Awasthi S, Lubinski J, Shaw C, Barrett S, Cai M, Wang F, et al. Immunization with a vaccine combining herpes simplex virus 2 (HSV-2) glycoprotein C (gC) and gD subunits improves the protection of dorsal root ganglia in mice and reduces the frequency of recurrent vaginal shedding of HSV-2 DNA in guinea pigs compar. J Virol. 2011;85:10472-86 pubmed publisher

product information

Antigen :

CD8a

Apps. Abbrev. :

Flow Cytometry

Cat # :

300925

Clone :

HIT8a

Item :

APC/Cyanine7 anti-human CD8a

Isotype :

Mouse IgG1, κ

Other Names :

T8, Leu2

Size :

25 tests

Price (USD) :

143 USD

Reactivity :

Human, Cross-Reactivity: Chimpanzee, Marmoset

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC_CYANINE7

Application Notes :

Clone HIT8a recognizes the alpha chain of CD8 5 . It does not block the binding of RPA-T8 antibody to CD8a. Additional reported applications of this antibody (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections 5,6 . This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue.

more info or order :

BioLegend product webpage