APC anti-human CD8a | BioLegend 300912 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-human CD8a

catalog :

300912

quantity :

100 tests

price :

121 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

Hit8a

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 4c	Trabanelli S, Lecciso M, Salvestrini V, Cavo M, OÄadlÃkovÃ¡ D, Lemoli R, et al. PGE2-induced IDO1 inhibits the capacity of fully mature DCs to elicit an in vitro antileukemic immune response. J Immunol Res. 2015;2015:253191 pubmed publisher
	Park J, Santich B, Xu H, Lum L, Cheung N. Potent ex vivo armed T cells using recombinant bispecific antibodies for adoptive immunotherapy with reduced cytokine release. J Immunother Cancer. 2021;9: pubmed publisher
	Perelman S, James D, Boguslawski K, Nelson C, Ilmain J, Zwack E, et al. Genetic variation of staphylococcal LukAB toxin determines receptor tropism. Nat Microbiol. 2021;6:731-745 pubmed publisher
	Wallace J, Alosaimi M, Khayat C, Jaber F, Almutairi A, Beaussant Cohen S, et al. ITK deficiency presenting as autoimmune lymphoproliferative syndrome. J Allergy Clin Immunol. 2021;147:743-745.e1 pubmed publisher
	Holokai L, Chakrabarti J, Lundy J, Croagh D, Adhikary P, Richards S, et al. Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma. Cancers (Basel). 2020;12: pubmed publisher
	Park J, Cheung N. GD2 or HER2 targeting T cell engaging bispecific antibodies to treat osteosarcoma. J Hematol Oncol. 2020;13:172 pubmed publisher
	Yang W, Yu T, Huang X, Bilotta A, Xu L, Lu Y, et al. Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity. Nat Commun. 2020;11:4457 pubmed publisher
	Rodriguez Garcia A, Sharma P, Poussin M, Boesteanu A, Minutolo N, Gitto S, et al. CAR T Cells Targeting MISIIR for the Treatment of Ovarian Cancer and Other Gynecologic Malignancies. Mol Ther. 2020;28:548-560 pubmed publisher
	Vlkova M, Chovancova Z, Nechvatalova J, Connelly A, Davis M, Slanina P, et al. Neutrophil and Granulocytic Myeloid-Derived Suppressor Cell-Mediated T Cell Suppression Significantly Contributes to Immune Dysregulation in Common Variable Immunodeficiency Disorders. J Immunol. 2019;202:93-104 pubmed publisher
	Uniken Venema W, Voskuil M, Vila A, van der Vries G, Jansen B, Jabri B, et al. Single-Cell RNA Sequencing of Blood and Ileal T Cells From Patients With Crohn's Disease Reveals Tissue-Specific Characteristics and Drug Targets. Gastroenterology. 2019;156:812-815.e22 pubmed publisher
	Cornelius C, Schöneweis K, Georgi F, Weber M, Niederberger V, Zieglmayer P, et al. Immunotherapy With the PreS-based Grass Pollen Allergy Vaccine BM32 Induces Antibody Responses Protecting Against Hepatitis B Infection. EBioMedicine. 2016;11:58-67 pubmed publisher
	Tatovic D, Young P, Kochba E, Levin Y, Wong F, Dayan C. Fine-Needle Aspiration Biopsy of the Lymph Node: A Novel Tool for the Monitoring of Immune Responses after Skin Antigen Delivery. J Immunol. 2015;195:386-92 pubmed publisher
	Ernst W, Zimara N, Hanses F, Männel D, Seelbach Göbel B, Wege A. Humanized mice, a new model to study the influence of drug treatment on neonatal sepsis. Infect Immun. 2013;81:1520-31 pubmed publisher

product information

Antigen :

CD8a

Apps. Abbrev. :

Flow Cytometry

Cat # :

300912

Clone :

HIT8a

Item :

APC anti-human CD8a

Isotype :

Mouse IgG1, κ

Other Names :

T8, Leu2

Size :

100 tests

Price (USD) :

121 USD

Reactivity :

Human, Cross-Reactivity: Chimpanzee, Marmoset

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC

Application Notes :

Clone HIT8a recognizes the alpha chain of CD8 5 . It does not block the binding of RPA-T8 antibody to CD8a. Additional reported applications of this antibody (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections 5,6 . This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue.

more info or order :

BioLegend product webpage