product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human CD8a
catalog :
300911
quantity :
25 tests
price :
50 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
Hit8a
reactivity :
human
application :
flow cytometry
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 4c
Trabanelli S, Lecciso M, Salvestrini V, Cavo M, Očadlíková D, Lemoli R, et al. PGE2-induced IDO1 inhibits the capacity of fully mature DCs to elicit an in vitro antileukemic immune response. J Immunol Res. 2015;2015:253191 pubmed publisher
Yang W, Yu T, Huang X, Bilotta A, Xu L, Lu Y, et al. Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity. Nat Commun. 2020;11:4457 pubmed publisher
Vlkova M, Chovancova Z, Nechvatalova J, Connelly A, Davis M, Slanina P, et al. Neutrophil and Granulocytic Myeloid-Derived Suppressor Cell-Mediated T Cell Suppression Significantly Contributes to Immune Dysregulation in Common Variable Immunodeficiency Disorders. J Immunol. 2019;202:93-104 pubmed publisher
Uniken Venema W, Voskuil M, Vila A, van der Vries G, Jansen B, Jabri B, et al. Single-Cell RNA Sequencing of Blood and Ileal T Cells From Patients With Crohn's Disease Reveals Tissue-Specific Characteristics and Drug Targets. Gastroenterology. 2019;156:812-815.e22 pubmed publisher
Pan Y, Tian T, Park C, Lofftus S, Mei S, Liu X, et al. Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism. Nature. 2017;543:252-256 pubmed publisher
Cornelius C, Schöneweis K, Georgi F, Weber M, Niederberger V, Zieglmayer P, et al. Immunotherapy With the PreS-based Grass Pollen Allergy Vaccine BM32 Induces Antibody Responses Protecting Against Hepatitis B Infection. EBioMedicine. 2016;11:58-67 pubmed publisher
Tatovic D, Young P, Kochba E, Levin Y, Wong F, Dayan C. Fine-Needle Aspiration Biopsy of the Lymph Node: A Novel Tool for the Monitoring of Immune Responses after Skin Antigen Delivery. J Immunol. 2015;195:386-92 pubmed publisher
Ernst W, Zimara N, Hanses F, Männel D, Seelbach Göbel B, Wege A. Humanized mice, a new model to study the influence of drug treatment on neonatal sepsis. Infect Immun. 2013;81:1520-31 pubmed publisher
product information
Antigen :
CD8a
Apps. Abbrev. :
Flow Cytometry
Cat # :
300911
Clone :
HIT8a
Item :
APC anti-human CD8a
Isotype :
Mouse IgG1, κ
Other Names :
T8, Leu2
Size :
25 tests
Price (USD) :
50 USD
Reactivity :
Human, Cross-Reactivity: Chimpanzee, Marmoset
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Application Notes :
Clone HIT8a recognizes the alpha chain of CD8 5 . It does not block the binding of RPA-T8 antibody to CD8a. Additional reported applications of this antibody (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections 5,6 . This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA