PE anti-human CD8a | BioLegend 300908 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-human CD8a

catalog :

300908

quantity :

100 tests

price :

72 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

Hit8a

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 1c	Chen P, Katsuyama E, Satyam A, Li H, Rubio J, Jung S, et al. CD38 reduces mitochondrial fitness and cytotoxic T cell response against viral infection in lupus patients by suppressing mitophagy. Sci Adv. 2022;8:eabo4271 pubmed publisher
flow cytometry; human; fig 2f	Wang Y, Mohseni M, Grauel A, Diez J, Guan W, Liang S, et al. SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms. Sci Rep. 2021;11:1399 pubmed publisher
	Dziedzic K, Wegrzyn P, Gałezowski M, Bońkowska M, Grycuk K, Satała G, et al. Release of adenosine-induced immunosuppression: Comprehensive characterization of dual A2A/A2B receptor antagonist. Int Immunopharmacol. 2021;96:107645 pubmed publisher
	Wei Z, Zhang X, Yong T, Bie N, Zhan G, Li X, et al. Boosting anti-PD-1 therapy with metformin-loaded macrophage-derived microparticles. Nat Commun. 2021;12:440 pubmed publisher
	Sun Y, Wu L, Zhong Y, Zhou K, Hou Y, Wang Z, et al. Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma. Cell. 2021;184:404-421.e16 pubmed publisher
	Chulpanova D, Solovyeva V, James V, Arkhipova S, Gomzikova M, Garanina E, et al. Human Mesenchymal Stem Cells Overexpressing Interleukin 2 Can Suppress Proliferation of Neuroblastoma Cells in Co-Culture and Activate Mononuclear Cells In Vitro. Bioengineering (Basel). 2020;7: pubmed publisher
	Kim N, Kim H, Lee K, Hong Y, Cho J, Choi J, et al. Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma. Nat Commun. 2020;11:2285 pubmed publisher
	Ali A, Chiuppesi F, Nguyen M, Hausner M, Nguyen J, Kha M, et al. Chimeric Antigen Receptors Targeting Human Cytomegalovirus. J Infect Dis. 2020;222:853-862 pubmed publisher
	Saraiva D, Jacinto A, Borralho P, Braga S, Cabral M. HLA-DR in Cytotoxic T Lymphocytes Predicts Breast Cancer Patients' Response to Neoadjuvant Chemotherapy. Front Immunol. 2018;9:2605 pubmed publisher
	Dockry E, O Leary S, Gleeson L, Lyons J, Keane J, Gray S, et al. Epigenetic induction of CD1d expression primes lung cancer cells for killing by invariant natural killer T cells. Oncoimmunology. 2018;7:e1428156 pubmed publisher
	Horn L, Ciavattone N, Atkinson R, Woldergerima N, Wolf J, Clements V, et al. CD3xPDL1 bi-specific T cell engager (BiTE) simultaneously activates T cells and NKT cells, kills PDL1+ tumor cells, and extends the survival of tumor-bearing humanized mice. Oncotarget. 2017;8:57964-57980 pubmed publisher
	Dushyanthen S, Teo Z, Caramia F, Savas P, Mintoff C, Virassamy B, et al. Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer. Nat Commun. 2017;8:606 pubmed publisher
	Linedale R, Schmidt C, King B, Ganko A, Simpson F, Panizza B, et al. Elevated frequencies of CD8 T cells expressing PD-1, CTLA-4 and Tim-3 within tumour from perineural squamous cell carcinoma patients. PLoS ONE. 2017;12:e0175755 pubmed publisher

product information

Antigen :

CD8a

Apps. Abbrev. :

Flow Cytometry

Cat # :

300908

Clone :

HIT8a

Item :

PE anti-human CD8a

Isotype :

Mouse IgG1, κ

Other Names :

T8, Leu2

Size :

100 tests

Price (USD) :

72 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

Application Notes :

Clone HIT8a recognizes the alpha chain of CD8 5 . It does not block the binding of RPA-T8 antibody to CD8a. Additional reported applications of this antibody (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections 5,6 . This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue.

more info or order :

BioLegend product webpage