Brilliant Violet 785™ anti-human CD4 | BioLegend 300553 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 785™ anti-human CD4

catalog :

300553

quantity :

25 tests

price :

198 USD

clonality :

monoclonal

host :

mouse

conjugate :

Brilliant Violet 785

clone name :

RPA-T4

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
	Farhat A, Weiner A, Posner C, Kim Z, Orcutt Jahns B, Carlson S, et al. Modeling cell-specific dynamics and regulation of the common gamma chain cytokines. Cell Rep. 2021;35:109044 pubmed publisher
	Leylek R, Alcántara Hernández M, Granja J, Chavez M, Perez K, Diaz O, et al. Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity. Cell Rep. 2020;32:108180 pubmed publisher
	Dawson N, Lamarche C, Hoeppli R, Bergqvist P, Fung V, McIver E, et al. Systematic testing and specificity mapping of alloantigen-specific chimeric antigen receptors in regulatory T cells. JCI Insight. 2019;4: pubmed publisher
	Adel Patient K, Lezmi G, Castelli F, Blanc S, Bernard H, Soulaines P, et al. Deep analysis of immune response and metabolic signature in children with food protein induced enterocolitis to cow's milk. Clin Transl Allergy. 2018;8:38 pubmed publisher
	Kiniry B, Ganesh A, Critchfield J, Hunt P, Hecht F, Somsouk M, et al. Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection. Mucosal Immunol. 2017;10:1008-1020 pubmed publisher
	Zenaro E, Donini M, Dusi S. Induction of Th1/Th17 immune response by Mycobacterium tuberculosis: role of dectin-1, Mannose Receptor, and DC-SIGN. J Leukoc Biol. 2009;86:1393-401 pubmed publisher

product information

Antigen :

CD4

Apps. Abbrev. :

Flow Cytometry

Cat # :

300553

Clone :

RPA-T4

Item :

Brilliant Violet 785™ anti-human CD4

Isotype :

Mouse IgG1, κ

Other Names :

Size :

25 tests

Price (USD) :

198 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

BV785

Application Notes :

The RPA-T4 antibody binds to the D1 domain of CD4 (CDR1 and CDR3 epitopes) and can block HIV gp120 binding and inhibit syncytia formation. Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen sections 3,4,5 , blocking of T cell activation 1,2 , and spatial biology (IBEX) 10,11 . This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. The Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 300569 - 300574).

more info or order :

BioLegend product webpage