Brilliant Violet 570™ anti-human CD4 | BioLegend 300534 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 570™ anti-human CD4

catalog :

300534

quantity :

100 tests

price :

390 USD

clonality :

monoclonal

host :

mouse

conjugate :

Brilliant Violet 570

clone name :

RPA-T4

reactivity :

human, chimpanzee

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
	Christiansen M, Offersen R, Jensen J, Petersen M, Larsen C, Mogensen T. Identification of Novel Genetic Variants in CVID Patients With Autoimmunity, Autoinflammation, or Malignancy. Front Immunol. 2019;10:3022 pubmed publisher
	Schreurs R, Baumdick M, Sagebiel A, Kaufmann M, Mokry M, Klarenbeek P, et al. Human Fetal TNF-α-Cytokine-Producing CD4+ Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life. Immunity. 2019;50:462-476.e8 pubmed publisher
	Franchini D, Lanvin O, Tosolini M, Patras de Campaigno E, Cammas A, Péricart S, et al. Microtubule-Driven Stress Granule Dynamics Regulate Inhibitory Immune Checkpoint Expression in T Cells. Cell Rep. 2019;26:94-107.e7 pubmed publisher
	Day C, Abrahams D, Harris L, van Rooyen M, Stone L, de Kock M, et al. HIV-1 Infection Is Associated with Depletion and Functional Impairment of Mycobacterium tuberculosis-Specific CD4 T Cells in Individuals with Latent Tuberculosis Infection. J Immunol. 2017;199:2069-2080 pubmed publisher
	O Connor K, Read S, Wang M, Schibeci S, Eslam M, Ong A, et al. IFNL3/4 genotype is associated with altered immune cell populations in peripheral blood in chronic hepatitis C infection. Genes Immun. 2016;17:328-34 pubmed publisher

product information

Antigen :

CD4

Apps. Abbrev. :

Flow Cytometry

Cat # :

300534

Clone :

RPA-T4

Item :

Brilliant Violet 570™ anti-human CD4

Isotype :

Mouse IgG1, κ

Other Names :

Size :

100 tests

Price (USD) :

390 USD

Reactivity :

Human, Chimpanzee

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

BV570

Application Notes :

The RPA-T4 antibody binds to the D1 domain of CD4 (CDR1 and CDR3 epitopes) and can block HIV gp120 binding and inhibit syncytia formation. Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen sections 3,4,5 , and blocking of T cell activation 1,2 . This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. The LEAF™ purified antibody (Endotoxin 0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 300516).

more info or order :

BioLegend product webpage