This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
LEAF™ Purified anti-human CD2
catalog :
300212
quantity :
500 μg
price :
290 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
RPA-2.10
reactivity :
human, chimpanzee, Rhesus monkey
application :
flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments, mass cytometry
citations: 10
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s1d
Dias J, Boulouis C, Gorin J, van den Biggelaar R, Lal K, Gibbs A, et al. The CD4-CD8- MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8+ MAIT cell pool. Proc Natl Acad Sci U S A. 2018;115:E11513-E11522 pubmed publisher
  • mass cytometry; human; loading ...; fig 1j
See P, Dutertre C, Chen J, Günther P, McGovern N, Irac S, et al. Mapping the human DC lineage through the integration of high-dimensional techniques. Science. 2017;356: pubmed publisher
  • blocking or activating experiments; human; loading ...; fig 5
Djaoud Z, Guethlein L, Horowitz A, Azzi T, Nemat Gorgani N, Olive D, et al. Two alternate strategies for innate immunity to Epstein-Barr virus: One using NK cells and the other NK cells and ?? T cells. J Exp Med. 2017;214:1827-1841 pubmed publisher
  • flow cytometry; human; loading ...; fig s7e
Landtwing V, Raykova A, Pezzino G, Beziat V, Marcenaro E, Graf C, et al. Cognate HLA absence in trans diminishes human NK cell education. J Clin Invest. 2016;126:3772-3782 pubmed publisher
  • flow cytometry; human; loading ...; fig 1b
Rölle A, Halenius A, Ewen E, Cerwenka A, Hengel H, Momburg F. CD2-CD58 interactions are pivotal for the activation and function of adaptive natural killer cells in human cytomegalovirus infection. Eur J Immunol. 2016;46:2420-2425 pubmed publisher
Rosental B, Kowarsky M, Seita J, Corey D, Ishizuka K, Palmeri K, et al. Complex mammalian-like haematopoietic system found in a colonial chordate. Nature. 2018;564:425-429 pubmed publisher
Ye W, Chew M, Hou J, Lai F, Leopold S, Loo H, et al. Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway. PLoS Pathog. 2018;14:e1007298 pubmed publisher
Riether C, Schürch C, Bührer E, Hinterbrandner M, Huguenin A, Hoepner S, et al. CD70/CD27 signaling promotes blast stemness and is a viable therapeutic target in acute myeloid leukemia. J Exp Med. 2017;214:359-380 pubmed publisher
Perona Wright G, Mohrs K, Mohrs M. Sustained signaling by canonical helper T cell cytokines throughout the reactive lymph node. Nat Immunol. 2010;11:520-6 pubmed publisher
Glatman Zaretsky A, Taylor J, King I, Marshall F, Mohrs M, Pearce E. T follicular helper cells differentiate from Th2 cells in response to helminth antigens. J Exp Med. 2009;206:991-9 pubmed publisher
product information
Antigen :
CD2
Apps. Abbrev. :
Flow Cytometry, IHC-F
Cat # :
300212
Clone :
RPA-2.10
Item :
LEAF™ Purified anti-human CD2
Isotype :
Mouse IgG1, κ
Other Names :
LFA-2, T11, SRBC-R
Size :
500 μg
Price (USD) :
290 USD
Reactivity :
Human, African Green, Baboon, Capuchin Monkey, Chimpanzee, Cynomolgus, Pigtailed Macaque, Rhesus, Swine (Pig, Porcine)
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
LEAF
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections 6 and blocking of T cell activation 2 . The Ultra-LEAF™ purified antibody (Endotoxin 0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. Nos. 300239 300240).
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA