Spark Blue™ 550 anti-human CD11b (activated) (Flexi-Fluor™)

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Spark Blue™ 550 anti-human CD11b (activated) (Flexi-Fluor™)

catalog :

285295

quantity :

50 μg

price :

394 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CBRM1/5

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

product information

Antigen :

CD11b

Apps. Abbrev. :

Cat # :

285295

Clone :

CBRM1/5

Item :

Spark Blue™ 550 anti-human CD11b (activated) (Flexi-Fluor™)

Isotype :

Mouse IgG1, κ

Other Names :

Integrin αM chain, C3biR, CR3, Mac-1, Mo1, ITGAM

Size :

50 μg

Price (USD) :

394 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

SPKBL_550

Application Notes :

The CBRM1/5 antibody recognizes a subset of CD11b molecules on neutrophils and monocytes activated with chemoattractants or phorbol-esters. This antibody does not recognize "non-activated" CD11b. The epitope recognized by CBRM1/5 is contained in the I domain of the a chain. Clone CBRM1/5 binds the I domain, close to the ligand binding site. It recognizes a conformational change of the integrin^9.Additional reported applications (for the relevant formats) include: immunoprecipitation, and blocking cell adhesion to fibrinogen and ICAM-1^1. The CBRM1/5 antibody binds specifically to the activated form of CD11b. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 301408).;

more info or order :

BioLegend product webpage