product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC/Cyanine7 anti-rat CD4
catalog :
201518
quantity :
100 μg
price :
347 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC/Cy7
clone name :
W3/25
reactivity :
human, rat
application :
flow cytometry
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • flow cytometry; rat
Lehmann J, Härtig W, Seidel A, Füldner C, Hobohm C, Grosche J, et al. Inflammatory cell recruitment after experimental thromboembolic stroke in rats. Neuroscience. 2014;279:139-54 pubmed publisher
Yanai H, Dunn C, Park B, Coletta C, McDevitt R, McNeely T, et al. Male rat leukocyte population dynamics predict a window for intervention in aging. elife. 2022;11: pubmed publisher
Dasinger J, Abais Battad J, Bukowy J, Lund H, Alsheikh A, Fehrenbach D, et al. Dietary protein source contributes to the risk of developing maternal syndrome in the Dahl salt-sensitive rat. Pregnancy Hypertens. 2021;24:126-134 pubmed publisher
Abais Battad J, Saravia F, Lund H, Dasinger J, Fehrenbach D, Alsheikh A, et al. Dietary influences on the Dahl SS rat gut microbiota and its effects on salt-sensitive hypertension and renal damage. Acta Physiol (Oxf). 2021;232:e13662 pubmed publisher
Alsheikh A, Dasinger J, Abais Battad J, Fehrenbach D, Yang C, Cowley A, et al. CCL2 mediates early renal leukocyte infiltration during salt-sensitive hypertension. Am J Physiol Renal Physiol. 2020;318:F982-F993 pubmed publisher
Fehrenbach D, Dasinger J, Lund H, Zemaj J, Mattson D. Splenocyte transfer exacerbates salt-sensitive hypertension in rats. Exp Physiol. 2020;105:864-875 pubmed publisher
Li B, Dasgupta C, Huang L, Meng X, Zhang L. MiRNA-210 induces microglial activation and regulates microglia-mediated neuroinflammation in neonatal hypoxic-ischemic encephalopathy. Cell Mol Immunol. 2019;: pubmed publisher
Alsheikh A, Lund H, Dasinger J, Abais Battad J, Fehrenbach D, Mattson D. Renal nerves and leukocyte infiltration in the kidney during salt-sensitive hypertension. Am J Physiol Regul Integr Comp Physiol. 2019;317:R182-R189 pubmed publisher
Pai A, Maddox T, Sandberg K. T Cells and Hypertension: Solved and Unsolved Mysteries Regarding the Female Rat. Physiology (Bethesda). 2018;33:254-260 pubmed publisher
Ruppert K, Nguyen T, Prabhakara K, Toledano Furman N, Srivastava A, Harting M, et al. Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Modify Microglial Response and Improve Clinical Outcomes in Experimental Spinal Cord Injury. Sci Rep. 2018;8:480 pubmed publisher
Xie L, Sun F, Wang J, Mao X, Xie L, Yang S, et al. mTOR signaling inhibition modulates macrophage/microglia-mediated neuroinflammation and secondary injury via regulatory T cells after focal ischemia. J Immunol. 2014;192:6009-19 pubmed publisher
Almolda B, Costa M, Montoya M, Gonzalez B, Castellano B. Increase in Th17 and T-reg lymphocytes and decrease of IL22 correlate with the recovery phase of acute EAE in rat. PLoS ONE. 2011;6:e27473 pubmed publisher
Kurtz C, Carey H. Seasonal changes in the intestinal immune system of hibernating ground squirrels. Dev Comp Immunol. 2007;31:415-28 pubmed
product information
Antigen :
CD4
Apps. Abbrev. :
FC
Cat # :
201518
Clone :
W3/25
Item :
APC/Cyanine7 anti-rat CD4
Isotype :
Mouse IgG1, κ
Other Names :
T4, L3T4, W3/25
Size :
100 μg
Price (USD) :
347 USD
Reactivity :
Rat
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC_CYANINE7
Immunogen :
Rat thymocyte membrane glycoproteins
Application Notes :
The W3/25 antibody has been shown to inhibit IL-2 production by T helper cells and to prevent autoimmune T cell transfer in an MBP induced EAE model in vivo. Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen sections^1,2, inhibition of IL-2 production^3, inhibition of MBP-induced T cell activation in EAE transfer model^3.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA