product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 488 anti-rat CD4
catalog :
201511
quantity :
25 μg
price :
101 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF488
clone name :
W3/25
reactivity :
rat
application :
immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • flow cytometry; rat; loading ...; fig 10b
Bath N, Verhoven B, Wilson N, Zeng W, Zhong W, Coons L, et al. APRIL/BLyS deficient rats prevent donor specific antibody (DSA) production and cell proliferation in rodent kidney transplant model. PLoS ONE. 2022;17:e0275564 pubmed publisher
  • flow cytometry; rat; loading ...; fig 15a
Bath N, Ding X, Wilson N, Verhoven B, Boldt B, Sukhwal A, et al. Desensitization and treatment with APRIL/BLyS blockade in rodent kidney transplant model. PLoS ONE. 2019;14:e0211865 pubmed publisher
  • immunocytochemistry; rat
Nuccitelli R, Berridge J, Mallon Z, Kreis M, Athos B, Nuccitelli P. Nanoelectroablation of Murine Tumors Triggers a CD8-Dependent Inhibition of Secondary Tumor Growth. PLoS ONE. 2015;10:e0134364 pubmed publisher
Qiu T, Li D, Liu Y, Ren H, Yang X, Luo W. Astragaloside IV Inhibits the Proliferation of Human Uterine Leiomyomas by Targeting IDO1. Cancers (Basel). 2022;14: pubmed publisher
Kastelberg B, Tubau Juni N, Ayubi T, Leung A, Leber A, Hontecillas R, et al. NLRX1 is a key regulator of immune signaling during invasive pulmonary aspergillosis. PLoS Pathog. 2020;16:e1008854 pubmed publisher
Yang W, Yu T, Huang X, Bilotta A, Xu L, Lu Y, et al. Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity. Nat Commun. 2020;11:4457 pubmed publisher
Ramanan D, Sefik E, Galván Peña S, Wu M, Yang L, Yang Z, et al. An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint. Cell. 2020;181:1276-1290.e13 pubmed publisher
Ding Y, Chen M, Wang Q, Gao L, Feng Y, Wang S, et al. Integrating Pharmacology and Microbial Network Analysis with Experimental Validation to Reveal the Mechanism of Composite Sophora Colon-Soluble Capsule against Ulcerative Colitis. Evid Based Complement Alternat Med. 2020;2020:9521073 pubmed publisher
He J, Yang Q, Xiao Q, Lei A, Li X, Zhou P, et al. IRF-7 Is a Critical Regulator of Type 2 Innate Lymphoid Cells in Allergic Airway Inflammation. Cell Rep. 2019;29:2718-2730.e6 pubmed publisher
Jin C, Lagoudas G, Zhao C, Bullman S, Bhutkar A, Hu B, et al. Commensal Microbiota Promote Lung Cancer Development via γδ T Cells. Cell. 2019;176:998-1013.e16 pubmed publisher
Zhong J, Scholz T, Yau A, Guérard S, Huffmeier U, Burkhardt H, et al. Mannan-induced Nos2 in macrophages enhances IL-17-driven psoriatic arthritis by innate lymphocytes. Sci Adv. 2018;4:eaas9864 pubmed publisher
Xiao L, Zhu L, Yang S, Lei D, Xiao Y, Peng B. Different correlation of sphingosine-1-phosphate receptor 1 with receptor activator of nuclear factor kappa B ligand and regulatory T cells in rat periapical lesions. J Endod. 2015;41:479-86 pubmed publisher
Kurtz C, Carey H. Seasonal changes in the intestinal immune system of hibernating ground squirrels. Dev Comp Immunol. 2007;31:415-28 pubmed
product information
Antigen :
CD4
Apps. Abbrev. :
FC, IHC-F
Cat # :
201511
Clone :
W3/25
Item :
Alexa Fluor® 488 anti-rat CD4
Isotype :
Mouse IgG1, κ
Other Names :
T4, L3T4, W3/25
Size :
25 μg
Price (USD) :
101 USD
Reactivity :
Rat
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
A488
Immunogen :
Rat thymocyte membrane glycoproteins
Application Notes :
The W3/25 antibody has been shown to inhibit IL-2 production by T helper cells and to prevent autoimmune T cell transfer in an MBP induced EAE model in vivo. Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen sections^1,2, inhibition of IL-2 production^3, inhibition of MBP-induced T cell activation in EAE transfer model^3.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA