product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 647 anti-rat CD3
catalog :
201408
quantity :
100 μg
price :
229 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF647
clone name :
1F4
reactivity :
rat
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • flow cytometry; rat; loading ...; fig s1k
Lodygin D, Hermann M, Schweingruber N, Flügel Koch C, Watanabe T, Schlosser C, et al. β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration. Nature. 2019;566:503-508 pubmed publisher
  • flow cytometry; rat; 1:200; loading ...; fig 4b
Pridans C, Raper A, Davis G, Alves J, Sauter K, Lefèvre L, et al. Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Csf1r Locus. J Immunol. 2018;201:2683-2699 pubmed publisher
  • flow cytometry; rat; loading ...; fig 9A
Reese S, Wilson N, Huang G, Redfield R, Zhong W, Djamali A. Calcineurin Inhibitor Minimization With Ixazomib, an Investigational Proteasome Inhibitor, for the Prevention of Antibody Mediated Rejection in a Preclinical Model. Transplantation. 2015;99:1785-95 pubmed publisher
  • flow cytometry; rat; 1:200
Kumar P, Kretzschmar B, Herold S, Nau R, Kreutzfeldt M, Schütze S, et al. Beneficial effect of chronic Staphylococcus aureus infection in a model of multiple sclerosis is mediated through the secretion of extracellular adherence protein. J Neuroinflammation. 2015;12:22 pubmed publisher
Ding X, Wilson N, Redfield R, Panzer S, Verhoven B, Reese S, et al. Oxidized-ATP Attenuates Kidney Allograft Rejection By Inhibiting T-Cell, B-Cell, and Macrophage Activity. Kidney360. 2020;1:106-114 pubmed publisher
Du T, Yang C, Ge M, Liu Y, Zhang P, Li H, et al. M1 Macrophage Derived Exosomes Aggravate Experimental Autoimmune Neuritis via Modulating Th1 Response. Front Immunol. 2020;11:1603 pubmed publisher
Schadt L, Sparano C, Schweiger N, Silina K, Cecconi V, Lucchiari G, et al. Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity. Cell Rep. 2019;29:1236-1248.e7 pubmed publisher
Li X, Chaudry I, Choudhry M. ERK and not p38 pathway is required for IL-12 restoration of T cell IL-2 and IFN-gamma in a rodent model of alcohol intoxication and burn injury. J Immunol. 2009;183:3955-62 pubmed publisher
product information
Antigen :
CD3
Apps. Abbrev. :
FC, IHC-F
Cat # :
201408
Clone :
1F4
Item :
Alexa Fluor® 647 anti-rat CD3
Isotype :
Mouse IgM, κ
Other Names :
T cell antigen receptor complex, T3
Size :
100 μg
Price (USD) :
229 USD
Reactivity :
Rat
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
A647
Immunogen :
F344 rat spleen cells stimulated with PMA and calcium ionophore
Application Notes :
Immobilized 1F4 antibody can induce T cell proliferation in vitro. Additional reported applications (for relevant formats of this clone) include: immunohistochemistry of acetone-fixed frozen sections^1 and formaldehyde- fixed paraffin embedded sections^4,5 immunofluorescence microscopy^3, in vivo activation of T cell responses^1, and in vivo inhibition of T cell responses^2.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA