product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 647 anti-rat TCR αβ
catalog :
201116
quantity :
100 μg
price :
229 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF647
clone name :
R73
reactivity :
rat
application :
flow cytometry
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • flow cytometry; rat; loading ...; fig s1c
Lodygin D, Hermann M, Schweingruber N, Flügel Koch C, Watanabe T, Schlosser C, et al. β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration. Nature. 2019;566:503-508 pubmed publisher
  • flow cytometry; rat; fig 2
Tuncel J, Haag S, Holmdahl R. MHC class II alleles associated with Th1 rather than Th17 type immunity drive the onset of early arthritis in a rat model of rheumatoid arthritis. Eur J Immunol. 2017;47:563-574 pubmed publisher
  • flow cytometry; rat
Schläger C, Körner H, Krueger M, Vidoli S, Haberl M, Mielke D, et al. Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid. Nature. 2016;530:349-53 pubmed publisher
  • flow cytometry; rat; fig 6
Haag S, Tuncel J, Thordardottir S, Mason D, Yau A, Dobritzsch D, et al. Positional identification of RT1-B (HLA-DQ) as susceptibility locus for autoimmune arthritis. J Immunol. 2015;194:2539-50 pubmed publisher
  • flow cytometry; rat; fig 3
Xie L, Choudhury G, Winters A, Yang S, Jin K. Cerebral regulatory T cells restrain microglia/macrophage-mediated inflammatory responses via IL-10. Eur J Immunol. 2015;45:180-91 pubmed publisher
Winkler A, Wrzos C, Haberl M, Weil M, Gao M, Mobius W, et al. Blood-brain barrier resealing in neuromyelitis optica occurs independently of astrocyte regeneration. J Clin Invest. 2021;131: pubmed publisher
Xiao S, Bod L, Pochet N, KOTA S, Hu D, Madi A, et al. Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation. Cell Rep. 2020;32:107892 pubmed publisher
Zander R, SCHAUDER D, Xin G, Nguyen C, Wu X, ZAJAC A, et al. CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer. Immunity. 2019;51:1028-1042.e4 pubmed publisher
Elsner R, Shlomchik M. IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression. Cell Rep. 2019;29:2796-2809.e5 pubmed publisher
Jin C, Lagoudas G, Zhao C, Bullman S, Bhutkar A, Hu B, et al. Commensal Microbiota Promote Lung Cancer Development via γδ T Cells. Cell. 2019;176:998-1013.e16 pubmed publisher
Stojic Vukanic Z, Kotur Stevuljevic J, Nacka Aleksić M, Kosec D, Vujnović I, Pilipovic I, et al. Sex Bias in Pathogenesis of Autoimmune Neuroinflammation: Relevance for Dimethyl Fumarate Immunomodulatory/Anti-oxidant Action. Mol Neurobiol. 2018;55:3755-3774 pubmed publisher
Nacka Aleksić M, Djikić J, Pilipović I, Stojić Vukanić Z, Kosec D, Bufan B, et al. Male rats develop more severe experimental autoimmune encephalomyelitis than female rats: sexual dimorphism and diergism at the spinal cord level. Brain Behav Immun. 2015;49:101-18 pubmed publisher
Djikić J, Nacka Aleksić M, Pilipovic I, Stojic Vukanic Z, Bufan B, Kosec D, et al. Age-associated changes in rat immune system: lessons learned from experimental autoimmune encephalomyelitis. Exp Gerontol. 2014;58:179-97 pubmed publisher
Xie L, Sun F, Wang J, Mao X, Xie L, Yang S, et al. mTOR signaling inhibition modulates macrophage/microglia-mediated neuroinflammation and secondary injury via regulatory T cells after focal ischemia. J Immunol. 2014;192:6009-19 pubmed publisher
product information
Antigen :
TCR alphabeta
Apps. Abbrev. :
FC
Cat # :
201116
Clone :
R73
Item :
Alexa Fluor® 647 anti-rat TCR αβ
Isotype :
Mouse (BALB/c) IgG1, κ
Other Names :
TCR α/β, α/β TCR
Size :
100 μg
Price (USD) :
229 USD
Reactivity :
Rat
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
A647
Immunogen :
Rat T cell blasts & erythrocytes
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation, Western blotting^3, immunohistochemical staining of acetone-fixed frozen sections^1, in vitro activation of α/β TCR^+ T cells ^1,2 and in vivo depletion^2 of α/β TCR^+ T cells . The LEAF™ purified antibody (Endotoxin <0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 201112).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA