product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse Perforin
catalog :
154306
quantity :
100 μg
price :
372 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
S16009A
reactivity :
mouse
application :
immunocytochemistry
more info or order :
citations: 22
Reference
Pan Y, Shu G, Fu L, Huang K, Zhou X, Gui C, et al. EHBP1L1 Drives Immune Evasion in Renal Cell Carcinoma through Binding and Stabilizing JAK1. Adv Sci (Weinh). 2023;10:e2206792 pubmed publisher
Xu W, Patel C, Zhao L, Sun I, Oh M, Sun I, et al. GOT1 regulates CD8+ effector and memory T cell generation. Cell Rep. 2023;42:111987 pubmed publisher
Yang H, Zhang X, Lao M, Sun K, He L, Xu J, et al. Targeting ubiquitin-specific protease 8 sensitizes anti-programmed death-ligand 1 immunotherapy of pancreatic cancer. Cell Death Differ. 2023;30:560-575 pubmed publisher
Liu L, Hou Y, Deng C, Tao Z, Chen Z, Hu J, et al. Single cell sequencing reveals that CD39 inhibition mediates changes to the tumor microenvironment. Nat Commun. 2022;13:6740 pubmed publisher
Shen H, Huang F, Zhang X, Ojo O, Li Y, Trummell H, et al. Selective suppression of melanoma lacking IFN-γ pathway by JAK inhibition depends on T cells and host TNF signaling. Nat Commun. 2022;13:5013 pubmed publisher
Wang M, Wu M, Liu X, Shao S, Huang J, Liu B, et al. Pyroptosis Remodeling Tumor Microenvironment to Enhance Pancreatic Cancer Immunotherapy Driven by Membrane Anchoring Photosensitizer. Adv Sci (Weinh). 2022;9:e2202914 pubmed publisher
Wang W, Guo M, Li N, Pang D, Wu J. Glutamine deprivation impairs function of infiltrating CD8+ T cells in hepatocellular carcinoma by inducing mitochondrial damage and apoptosis. World J Gastrointest Oncol. 2022;14:1124-1140 pubmed publisher
Chandana M, Anand A, Ghosh S, Das R, Beura S, Jena S, et al. Malaria parasite heme biosynthesis promotes and griseofulvin protects against cerebral malaria in mice. Nat Commun. 2022;13:4028 pubmed publisher
Campisi L, Chizari S, Ho J, Gromova A, Arnold F, Mosca L, et al. Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4. Nature. 2022;606:945-952 pubmed publisher
Macchi C, Moregola A, Greco M, Svecla M, Bonacina F, Dhup S, et al. Monocarboxylate transporter 1 deficiency impacts CD8+ T lymphocytes proliferation and recruitment to adipose tissue during obesity. iScience. 2022;25:104435 pubmed publisher
Pathania A, Prathipati P, Olwenyi O, Chava S, Smith O, Gupta S, et al. miR-15a and miR-15b modulate natural killer and CD8+T-cell activation and anti-tumor immune response by targeting PD-L1 in neuroblastoma. Mol Ther Oncolytics. 2022;25:308-329 pubmed publisher
Jia J, Liao X, Liang Y, Chen R, Gao F. K48- and K27-mutant ubiquitin regulates adaptive immune response by affecting cross-presentation in bone marrow precursor cells. J Leukoc Biol. 2022;112:157-172 pubmed publisher
Li H, Xiao Y, Li Q, Yao J, Yuan X, Zhang Y, et al. The allergy mediator histamine confers resistance to immunotherapy in cancer patients via activation of the macrophage histamine receptor H1. Cancer Cell. 2022;40:36-52.e9 pubmed publisher
Reyes R, Zhang C, Deng Y, Ji N, Mukherjee N, Padrón A, et al. CD122-targeted interleukin-2 and αPD-L1 treat bladder cancer and melanoma via distinct mechanisms, including CD122-driven natural killer cell maturation. Oncoimmunology. 2021;10:2006529 pubmed publisher
Jiang P, Zhang Y, Ru B, Yang Y, Vu T, Paul R, et al. Systematic investigation of cytokine signaling activity at the tissue and single-cell levels. Nat Methods. 2021;18:1181-1191 pubmed publisher
Lou Y, Wang J, Peng P, Wang S, Liu P, Xu L. Downregulated TNF-α Levels after Cryo-Thermal Therapy Drive Tregs Fragility to Promote Long-Term Antitumor Immunity. Int J Mol Sci. 2021;22: pubmed publisher
Zhang X, Huang X, Xu J, Li E, Lao M, Tang T, et al. NEK2 inhibition triggers anti-pancreatic cancer immunity by targeting PD-L1. Nat Commun. 2021;12:4536 pubmed publisher
Melo Silva C, Alves Peixoto P, Heath N, Tang L, Montoya B, Knudson C, et al. Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells. PLoS Pathog. 2021;17:e1009593 pubmed publisher
Goggi J, Tan Y, Hartimath S, Jieu B, Hwang Y, Jiang L, et al. Granzyme B PET Imaging of Immune Checkpoint Inhibitor Combinations in Colon Cancer Phenotypes. Mol Imaging Biol. 2020;22:1392-1402 pubmed publisher
Wu J, Dobbs N, Yang K, Yan N. Interferon-Independent Activities of Mammalian STING Mediate Antiviral Response and Tumor Immune Evasion. Immunity. 2020;53:115-126.e5 pubmed publisher
Lu Y, Zhao Q, Liao J, Song E, Xia Q, Pan J, et al. Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity. Cell. 2020;180:1081-1097.e24 pubmed publisher
Sade Feldman M, Yizhak K, Bjorgaard S, Ray J, de Boer C, Jenkins R, et al. Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma. Cell. 2018;175:998-1013.e20 pubmed publisher
product information
Antigen :
Perforin
Apps. Abbrev. :
ICFC
Cat # :
154306
Clone :
S16009A
Item :
PE anti-mouse Perforin
Isotype :
Rat IgG2a, κ
Other Names :
Prf1, Pfp, Pfn, Pfn-1
Size :
100 μg
Price (USD) :
372 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PE
Immunogen :
Mouse perforin transfected cells.
Application Notes :
Clone S16009A reacts with perforin from both C57BL/6 and BALB/c strains.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA