product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-mouse P2X7R
catalog :
148706
quantity :
100 μg
price :
332 USD
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
1F11
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 6
Reference
Lin Y, Duong H, Limary A, Kim E, Hsu P, Patel S, et al. Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes. Immunity. 2023;56:207-223.e8 pubmed publisher
Wanhainen K, Peng C, Zhou M, Macedo B, O Flanagan S, Yang T, et al. P2RX7 Enhances Tumor Control by CD8+ T Cells in Adoptive Cell Therapy. Cancer Immunol Res. 2022;10:871-884 pubmed publisher
Hiltensperger M, Beltrán E, Kant R, Tyystjärvi S, Lepennetier G, Domínguez Moreno H, et al. Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity. Nat Immunol. 2021;22:880-892 pubmed publisher
Borges da Silva H, Peng C, Wang H, Wanhainen K, Ma C, Lopez S, et al. Sensing of ATP via the Purinergic Receptor P2RX7 Promotes CD8+ Trm Cell Generation by Enhancing Their Sensitivity to the Cytokine TGF-β. Immunity. 2020;53:158-171.e6 pubmed publisher
Zhou Y, Fei M, Zhang G, Liang W, Lin W, Wu Y, et al. Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP. Immunity. 2020;52:357-373.e9 pubmed publisher
Bhattacharya A, Lord B, Grigoleit J, He Y, Fraser I, Campbell S, et al. Neuropsychopharmacology of JNJ-55308942: evaluation of a clinical candidate targeting P2X7 ion channels in animal models of neuroinflammation and anhedonia. Neuropsychopharmacology. 2018;43:2586-2596 pubmed publisher
product information
Antigen :
P2X7R
Apps. Abbrev. :
FC
Cat # :
148706
Clone :
1F11
Item :
APC anti-mouse P2X7R
Isotype :
Rat IgG2b, κ
Other Names :
P2X7 receptor (P2X7R), P2RX7
Size :
100 μg
Price (USD) :
332 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
APC
Immunogen :
Murine colon mast cells
Application Notes :
Additional reported applications for the relevant formats include: immunoprecipitation^1, Western blotting^1, immunohistochemistry^1, in vivo inhibition of intestinal inflammation and mast cell activation^1.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA