Ultra-LEAF™ Purified anti-mouse/human LAP (TGF-β1) | BioLegend 146704 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Ultra-LEAF™ Purified anti-mouse/human LAP (TGF-β1)

catalog :

146704

quantity :

1 mg

price :

644 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

TW7-28G11

reactivity :

human, mouse

application :

western blot, neutralization, immunoprecipitation, flow cytometry

more info or order :

BioLegend product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 4c	Dong X, Zhao B, Iacob R, Zhu J, Koksal A, Lu C, et al. Force interacts with macromolecular structure in activation of TGF-?. Nature. 2017;542:55-59 pubmed publisher
	Bartoccetti M, van der Veer B, Luo X, Khoueiry R, She P, Bajaj M, et al. Regulatory Dynamics of Tet1 and Oct4 Resolve Stages of Global DNA Demethylation and Transcriptomic Changes in Reprogramming. Cell Rep. 2020;30:2150-2169.e9 pubmed publisher

product information

Antigen :

LAP

Apps. Abbrev. :

FC, WB, IP, Neut

Cat # :

146704

Clone :

TW7-28G11

Item :

Ultra-LEAF™ Purified anti-mouse/human LAP (TGF-β1)

Isotype :

Mouse IgG2b, κ

Other Names :

TGFB, TGFB1, DPD1, Latency Associated Peptide (LAP), TGF-β1, TGF-β, TGF-beta1

Size :

1 mg

Price (USD) :

644 USD

Reactivity :

Mouse, Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

ULEAF

Immunogen :

Mouse Tgfb1'transduced P3U1 cells

Application Notes :

Several anti-LAP antibody clones have been compared and characterized for their LAP reactivity.^2 TW7-28G11 recognizes conformation specific latent TGF-β complex (LAP + TGF-β) and pro-TGF-β1, but not free LAP or active TGF-β.Additional reported applications (for relevant formats) include: Western blotting^1, immunoprecipitation^1, and neutralization^2. TW7-28G11 is able to neutralize TGF-β activity.;

more info or order :

BioLegend product webpage