Ultra-LEAF™ Purified anti-mouse/human LAP (TGF-β1) | BioLegend 146703 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Ultra-LEAF™ Purified anti-mouse/human LAP (TGF-β1)

catalog :

146703

quantity :

100 μg

price :

171 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

TW7-28G11

reactivity :

human, mouse

application :

western blot, neutralization, immunoprecipitation, flow cytometry

more info or order :

BioLegend product webpage

citations: 1

Reference
Dong X, Zhao B, Iacob R, Zhu J, Koksal A, Lu C, et al. Force interacts with macromolecular structure in activation of TGF-?. Nature. 2017;542:55-59 pubmed publisher

product information

Antigen :

LAP

Apps. Abbrev. :

FC, WB, IP, Neut

Cat # :

146703

Clone :

TW7-28G11

Item :

Ultra-LEAF™ Purified anti-mouse/human LAP (TGF-β1)

Isotype :

Mouse IgG2b, κ

Other Names :

TGFB, TGFB1, DPD1, Latency Associated Peptide (LAP), TGF-β1, TGF-β, TGF-beta1

Size :

100 μg

Price (USD) :

171 USD

Reactivity :

Mouse, Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

ULEAF

Immunogen :

Mouse Tgfb1'transduced P3U1 cells

Application Notes :

Several anti-LAP antibody clones have been compared and characterized for their LAP reactivity.^2 TW7-28G11 recognizes conformation specific latent TGF-β complex (LAP + TGF-β) and pro-TGF-β1, but not free LAP or active TGF-β.Additional reported applications (for relevant formats) include: Western blotting^1, immunoprecipitation^1, and neutralization^2. TW7-28G11 is able to neutralize TGF-β activity.;

more info or order :

BioLegend product webpage