product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Ultra-LEAF™ Purified anti-Asialo-GM1
catalog :
146002
quantity :
1 mL
price :
534 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
Poly21460
reactivity :
mouse
application :
flow cytometry, blocking or activating experiments
more info or order :
citations: 19
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; mouse; fig 8c
Manangeeswaran M, Lewkowicz A, Israely T, Ireland D, Verthelyi D. CpG Oligonucleotides Protect Mice From Alphavirus Encephalitis: Role of NK Cells, Interferons, and TNF. Front Immunol. 2020;11:237 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig s6
Gauthier L, Morel A, Anceriz N, Rossi B, Blanchard Alvarez A, Grondin G, et al. Multifunctional Natural Killer Cell Engagers Targeting NKp46 Trigger Protective Tumor Immunity. Cell. 2019;177:1701-1713.e16 pubmed publisher
  • blocking or activating experiments; mouse; fig 5f
Böttcher J, Bonavita E, Chakravarty P, Blees H, Cabeza Cabrerizo M, Sammicheli S, et al. NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control. Cell. 2018;172:1022-1037.e14 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 3c
Spiegel A, Brooks M, Houshyar S, Reinhardt F, Ardolino M, Fessler E, et al. Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells. Cancer Discov. 2016;6:630-49 pubmed publisher
Wang X, Zhang Y, Ben Y, Qiu C, Wu J, Zhang W, et al. Anti-HBc IgG Responses Occurring at the Early Phase of Infection Correlate Negatively with HBV Replication in a Mouse Model. Viruses. 2022;14: pubmed publisher
Ma Q, Chen Y, Qin Q, Guo F, Wang Y, Li D. CXCL13 expression in mouse 4T1 breast cancer microenvironment elicits antitumor immune response by regulating immune cell infiltration. Precis Clin Med. 2021;4:155-167 pubmed publisher
Pelly V, Moeini A, Roelofsen L, Bonavita E, Bell C, Hutton C, et al. Anti-Inflammatory Drugs Remodel the Tumor Immune Environment to Enhance Immune Checkpoint Blockade Efficacy. Cancer Discov. 2021;11:2602-2619 pubmed publisher
Lin Q, Rong L, Jia X, Li R, Yu B, Hu J, et al. IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella. Nat Commun. 2021;12:2537 pubmed publisher
Dubrot J, Lane Reticker S, Kessler E, Ayer A, Mishra G, Wolfe C, et al. In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma. Immunity. 2021;: pubmed publisher
Shannon J, Vrba S, Reynoso G, Wynne Jones E, Kamenyeva O, Malo C, et al. Group 1 innate lymphoid-cell-derived interferon-γ maintains anti-viral vigilance in the mucosal epithelium. Immunity. 2021;54:276-290.e5 pubmed publisher
Bonavita E, Bromley C, Jönsson G, Pelly V, Sahoo S, Walwyn Brown K, et al. Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade. Immunity. 2020;53:1215-1229.e8 pubmed publisher
Li P, Lu M, Shi J, Hua L, Gong Z, Li Q, et al. Dual roles of neutrophils in metastatic colonization are governed by the host NK cell status. Nat Commun. 2020;11:4387 pubmed publisher
Haabeth O, Hennig K, Fauskanger M, Løset G, Bogen B, Tveita A. CD4+ T-cell killing of multiple myeloma cells is mediated by resident bone marrow macrophages. Blood Adv. 2020;4:2595-2605 pubmed publisher
Andre P, Denis C, Soulas C, Bourbon Caillet C, Lopez J, Arnoux T, et al. Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells. Cell. 2018;175:1731-1743.e13 pubmed publisher
Turaj A, Hussain K, Cox K, Rose Zerilli M, Testa J, Dahal L, et al. Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment. Cancer Cell. 2017;32:777-791.e6 pubmed publisher
Dai H, Griffin N, Bolyard C, Mao H, Zhang J, Cripe T, et al. The Fc Domain of Immunoglobulin Is Sufficient to Bridge NK Cells with Virally Infected Cells. Immunity. 2017;47:159-170.e10 pubmed publisher
Kogo H, Shimizu M, Negishi Y, Uchida E, Takahashi H. Suppression of murine tumour growth through CD8+ cytotoxic T lymphocytes via activated DEC-205+ dendritic cells by sequential administration of ?-galactosylceramide in vivo. Immunology. 2017;151:324-339 pubmed publisher
Ren Y, Wang N, Hu W, Zhang X, Xu J, Wan Y. Successive site translocating inoculation potentiates DNA/recombinant vaccinia vaccination. Sci Rep. 2015;5:18099 pubmed publisher
Hu J, Crampton J, Cupo A, Ketas T, van Gils M, Sliepen K, et al. Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity. J Virol. 2015;89:10383-98 pubmed publisher
product information
Antigen :
Asialo-GM1
Apps. Abbrev. :
FC, Depletion
Cat # :
146002
Clone :
Poly21460
Item :
Ultra-LEAF™ Purified anti-Asialo-GM1
Isotype :
Rabbit Polyclonal IgG
Other Names :
Ganglioside, GM1, ganglio-N-tetraosylceramide
Size :
1 mL
Price (USD) :
534 USD
Reactivity :
Mouse, Rat
Clonality :
Polyclonal
Host :
Rabbit
Conjugate/Tag/Label :
ULEAF
Immunogen :
Asialo-GM1
Application Notes :
This antibody recognizes asialo-GM1. It does not react with other glycolipids, such as GM1 and Asialo-GM2.This antibody can partially block IL-12 induced IFN-γ production but does not affect other systemic action of IL-12. This product may contain other non-IgG subtypes.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA