product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-mouse CD284 (TLR4)
catalog :
145401
quantity :
25 μg
price :
77 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
SA15-21
reactivity :
mouse
application :
immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s1
Mai J, Li Z, Xia X, Zhang J, Li J, Liu H, et al. Synergistic Activation of Antitumor Immunity by a Particulate Therapeutic Vaccine. Adv Sci (Weinh). 2021;8:2100166 pubmed publisher
  • flow cytometry; mouse; fig 2
Yang L, Carrillo M, Wu Y, DiAngelo S, Silveyra P, Umstead T, et al. SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation. PLoS ONE. 2015;10:e0126576 pubmed publisher
  • immunocytochemistry; mouse
Chen G, Brown N, Wu W, Khedri Z, Yu H, Chen X, et al. Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1. elife. 2014;3:e04066 pubmed publisher
Mart xed nez Cuevas F, Cruz S, Gonz xe1 lez Espinosa C. Methadone Requires the Co-Activation of μ-Opioid and Toll-Like-4 Receptors to Produce Extracellular DNA Traps in Bone-Marrow-Derived Mast Cells. Int J Mol Sci. 2024;25: pubmed publisher
Aguilar Brise xf1 o J, Elliff J, Patten J, Wilson L, Davey R, Bailey A, et al. Effect of Interferon Gamma on Ebola Virus Infection of Primary Kupffer Cells and a Kupffer Cell Line. Viruses. 2023;15: pubmed publisher
Navia Pelaez J, Choi S, Dos Santos Aggum Capettini L, Xia Y, Gonen A, Agatisa Boyle C, et al. Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain. J Exp Med. 2021;218: pubmed publisher
Kothari V, Tang J, He Y, Kramer F, Kanter J, Bornfeldt K. ADAM17 Boosts Cholesterol Efflux and Downstream Effects of High-Density Lipoprotein on Inflammatory Pathways in Macrophages. Arterioscler Thromb Vasc Biol. 2021;41:1854-1873 pubmed publisher
Rosa J, Farré Alins V, Ortega M, Navarrete M, López Rodríguez A, Palomino Antolin A, et al. TLR4 pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury. Br J Pharmacol. 2021;178:3395-3413 pubmed publisher
Celorrio M, Abellanas M, Rhodes J, Goodwin V, Moritz J, Vadivelu S, et al. Gut microbial dysbiosis after traumatic brain injury modulates the immune response and impairs neurogenesis. Acta Neuropathol Commun. 2021;9:40 pubmed publisher
Lim T, Bunjamin M, Ruedl C, Su I. Talin1 controls dendritic cell activation by regulating TLR complex assembly and signaling. J Exp Med. 2020;217: pubmed publisher
Metz P, Ching K, Xie T, Delgado Cuenca P, Niessen S, Tatlock J, et al. Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling. Cell Rep. 2020;30:1935-1950.e8 pubmed publisher
Yang C, Briones M, Chiou J, Lei L, Patton M, Ma L, et al. Chlamydia trachomatis Lipopolysaccharide Evades the Canonical and Noncanonical Inflammatory Pathways To Subvert Innate Immunity. MBio. 2019;10: pubmed publisher
Tai Y, Lin L, Xing L, Cho S, Yu T, Acharya C, et al. APRIL signaling via TACI mediates immunosuppression by T regulatory cells in multiple myeloma: therapeutic implications. Leukemia. 2019;33:426-438 pubmed publisher
De Nardo D, Balka K, Cardona Gloria Y, Rao V, Latz E, Masters S. Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling. J Biol Chem. 2018;293:15195-15207 pubmed publisher
Matsuba S, Yabe Wada T, Takeda K, Sato T, Suyama M, Takai T, et al. Identification of Secretory Leukoprotease Inhibitor As an Endogenous Negative Regulator in Allergic Effector Cells. Front Immunol. 2017;8:1538 pubmed publisher
Sasaki K, Gotoh K, Miake S, Setoyama D, Yagi M, Igami K, et al. p32 is Required for Appropriate Interleukin-6 Production Upon LPS Stimulation and Protects Mice from Endotoxin Shock. EBioMedicine. 2017;20:161-172 pubmed publisher
Westphal A, Cheng W, Yu J, Grassl G, Krautkrämer M, Holst O, et al. Lysosomal trafficking regulator Lyst links membrane trafficking to toll-like receptor-mediated inflammatory responses. J Exp Med. 2017;214:227-244 pubmed publisher
product information
Antigen :
CD284
Apps. Abbrev. :
FC, IP
Cat # :
145401
Clone :
SA15-21
Item :
Purified anti-mouse CD284 (TLR4)
Isotype :
Rat IgG2a, κ
Other Names :
Toll-like Receptor 4/MD2 complex, TLR4-MD2-complex, TLR4/MD2, CD284/MD2
Size :
25 μg
Price (USD) :
77 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PURE
Immunogen :
LPS-stimulated TLR4/MD-2/CD14 cotransfected NKR cells.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA