product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Pacific Blue™ anti-MU/HU GL7 Antigen (T/B Cell Act. Marker)
catalog :
144613
quantity :
25 μg
price :
112 USD
clonality :
monoclonal
host :
rat
conjugate :
Pacific Blue
clone name :
GL7
reactivity :
mouse
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 33
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 5f
Lin J, Lv J, Yu S, Chen Y, Wang H, Chen J. Transcript Engineered Extracellular Vesicles Alleviate Alloreactive Dynamics in Renal Transplantation. Adv Sci (Weinh). 2022;9:e2202633 pubmed publisher
  • flow cytometry; mouse; 1:500; loading ...; fig 8a
Satofuka H, Abe S, Moriwaki T, Okada A, Kazuki K, Tanaka H, et al. Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci. Nat Commun. 2022;13:1841 pubmed publisher
  • flow cytometry; mouse
Bohannon C, Ende Z, Cao W, Mboko W, Ranjan P, Kumar A, et al. Influenza Virus Infects and Depletes Activated Adaptive Immune Responders. Adv Sci (Weinh). 2021;8:e2100693 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2e
  • flow cytometry; mouse; loading ...; fig 3d
Degn S, van der Poel C, Firl D, Ayoglu B, Al Qureshah F, Bajic G, et al. Clonal Evolution of Autoreactive Germinal Centers. Cell. 2017;170:913-926.e19 pubmed publisher
Yazicioglu Y, Marin E, Sandhu C, Galiani S, Raza I, Ali M, et al. Dynamic mitochondrial transcription and translation in B cells control germinal center entry and lymphomagenesis. Nat Immunol. 2023;24:991-1006 pubmed publisher
Hu Q, Xu T, Zhang M, Zhang H, Liu Y, Li H, et al. Diverging regulation of Bach2 protein and RNA expression determine cell fate in early B cell response. Cell Rep. 2022;40:111035 pubmed publisher
MacLean A, Richmond N, Koneva L, Attar M, Medina C, Thornton E, et al. Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites. Immunity. 2022;55:718-733.e8 pubmed publisher
Wittner J, Schulz S, Steinmetz T, Berges J, Hauke M, Channell W, et al. Krüppel-like factor 2 controls IgA plasma cell compartmentalization and IgA responses. Mucosal Immunol. 2022;15:668-682 pubmed publisher
Duan L, Liu D, Chen H, Mintz M, Chou M, Kotov D, et al. Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation. Immunity. 2021;54:2256-2272.e6 pubmed publisher
Glaros V, Rauschmeier R, Artemov A, Reinhardt A, Ols S, Emmanouilidi A, et al. Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response. Immunity. 2021;54:2005-2023.e10 pubmed publisher
Katsuyama T, Moulton V. Splicing factor SRSF1 is indispensable for regulatory T cell homeostasis and function. Cell Rep. 2021;36:109339 pubmed publisher
Mandal R, Denny J, Namazzi R, Opoka R, Datta D, John C, et al. Dynamic modulation of spleen germinal center reactions by gut bacteria during Plasmodium infection. Cell Rep. 2021;35:109094 pubmed publisher
Tacconi C, Commerford C, Dieterich L, Schwager S, He Y, Ikenberg K, et al. CD169+ lymph node macrophages have protective functions in mouse breast cancer metastasis. Cell Rep. 2021;35:108993 pubmed publisher
Frost J, Tan T, Abbas M, Wideman S, Bonadonna M, Stoffel N, et al. Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to Vaccination and Infection. Med. 2021;2:164-179.e12 pubmed publisher
Doron I, Leonardi I, Li X, Fiers W, Semon A, Bialt DeCelie M, et al. Human gut mycobiota tune immunity via CARD9-dependent induction of anti-fungal IgG antibodies. Cell. 2021;184:1017-1031.e14 pubmed publisher
Zhou X, Zhu X, Li C, Li Y, Ye Z, Shapiro V, et al. Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity. Cell Rep. 2021;34:108601 pubmed publisher
Alexandre Y, Devi S, Park S, Mackay L, Heath W, Mueller S. Systemic Inflammation Suppresses Lymphoid Tissue Remodeling and B Cell Immunity during Concomitant Local Infection. Cell Rep. 2020;33:108567 pubmed publisher
Waide M, Polidoro R, Powell W, Denny J, Kos J, Tieri D, et al. Gut Microbiota Composition Modulates the Magnitude and Quality of Germinal Centers during Plasmodium Infections. Cell Rep. 2020;33:108503 pubmed publisher
Simoni L, Presumey J, van der Poel C, Castrillón C, Chang S, Utz P, et al. Complement C4A Regulates Autoreactive B Cells in Murine Lupus. Cell Rep. 2020;33:108330 pubmed publisher
Huang W, Zhou S, He X, Chiem K, Mabrouk M, Nissly R, et al. SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination. Adv Mater. 2020;32:e2005637 pubmed publisher
Wong R, Belk J, Govero J, Uhrlaub J, Reinartz D, Zhao H, et al. Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses. Immunity. 2020;53:1078-1094.e7 pubmed publisher
Kato Y, Abbott R, Freeman B, Haupt S, Groschel B, Silva M, et al. Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo. Immunity. 2020;53:548-563.e8 pubmed publisher
Brooks J, Barber J, Davies J, Wells J, Steptoe R. Transfer of antigen-encoding bone marrow under immune-preserving conditions deletes mature antigen-specific B cells in recipients and inhibits antigen-specific antibody production. Cytotherapy. 2020;22:436-444 pubmed publisher
van der Poel C, Bajic G, Macaulay C, van den Broek T, Ellson C, Bouma G, et al. Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcγRIIB. Cell Rep. 2019;29:2745-2755.e4 pubmed publisher
Nagai M, Noguchi R, Takahashi D, Morikawa T, Koshida K, Komiyama S, et al. Fasting-Refeeding Impacts Immune Cell Dynamics and Mucosal Immune Responses. Cell. 2019;178:1072-1087.e14 pubmed publisher
Mintz M, Felce J, Chou M, Mayya V, Xu Y, Shui J, et al. The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis. Immunity. 2019;: pubmed publisher
Yue X, Lio C, Samaniego Castruita D, Li X, Rao A. Loss of TET2 and TET3 in regulatory T cells unleashes effector function. Nat Commun. 2019;10:2011 pubmed publisher
Andersen T, Huszthy P, Gopalakrishnan R, Jacobsen J, Fauskanger M, Tveita A, et al. Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules. NPJ Vaccines. 2019;4:9 pubmed publisher
Stewart I, Radtke D, Phillips B, McGowan S, Bannard O. Germinal Center B Cells Replace Their Antigen Receptors in Dark Zones and Fail Light Zone Entry when Immunoglobulin Gene Mutations are Damaging. Immunity. 2018;49:477-489.e7 pubmed publisher
Firl D, Degn S, PADERA T, Carroll M. Capturing change in clonal composition amongst single mouse germinal centers. elife. 2018;7: pubmed publisher
Rodda L, Lu E, Bennett M, Sokol C, Wang X, Luther S, et al. Single-Cell RNA Sequencing of Lymph Node Stromal Cells Reveals Niche-Associated Heterogeneity. Immunity. 2018;48:1014-1028.e6 pubmed publisher
Wu J, Zhang H, Shi X, Xiao X, Fan Y, Minze L, et al. Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction. Immunity. 2017;47:1114-1128.e6 pubmed publisher
Huang L, Zhang Y, Xu C, Gu X, Niu L, Wang J, et al. Rictor positively regulates B cell receptor signaling by modulating actin reorganization via ezrin. PLoS Biol. 2017;15:e2001750 pubmed publisher
product information
Antigen :
GL7
Apps. Abbrev. :
FC
Cat # :
144613
Clone :
GL7
Item :
Pacific Blue™ anti-MU/HU GL7 Antigen (T/B Cell Act. Marker)
Isotype :
Rat IgM, κ
Other Names :
Ly77, T and B cell activation marker
Size :
25 μg
Price (USD) :
112 USD
Reactivity :
Mouse, Human
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PB
Immunogen :
LPS activated DBA/J mouse B cells
Application Notes :
The GL7 antibody does not block the binding of CD22 with sulfated a2-6-sialyl-LacNAc.Cross-reactivity to ferret has been reported by a collaborator, but not verified in house.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA