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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-MU/HU GL7 Antigen (T/B Cell Act. Marker)
catalog :
144603
quantity :
50 μg
price :
90 USD
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
GL7
reactivity :
mouse
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 50
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 4f
Cao W, Fang F, Gould T, Li X, Kim C, Gustafson C, et al. Ecto-NTPDase CD39 is a negative checkpoint that inhibits follicular helper cell generation. J Clin Invest. 2020;130:3422-3436 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3e
Zhang Q, Xiang L, Zaman M, Dong W, He G, Deng G. Predominant Role of Immunoglobulin G in the Pathogenesis of Splenomegaly in Murine Lupus. Front Immunol. 2019;10:3020 pubmed publisher
  • flow cytometry; mouse; 1:120; loading ...; fig 1a
Koike T, Harada K, Horiuchi S, Kitamura D. The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 2a
Grootjans J, Krupka N, Hosomi S, Matute J, Hanley T, Saveljeva S, et al. Epithelial endoplasmic reticulum stress orchestrates a protective IgA response. Science. 2019;363:993-998 pubmed publisher
Menolfi D, Lee B, Zhang H, Jiang W, Bowen N, Wang Y, et al. ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion. Nat Commun. 2023;14:3618 pubmed publisher
Zhang Y, Paynter J, Antanasijevic A, Allen J, Eldad M, Lee Y, et al. Single-component multilayered self-assembling protein nanoparticles presenting glycan-trimmed uncleaved prefusion optimized envelope trimmers as HIV-1 vaccine candidates. Nat Commun. 2023;14:1985 pubmed publisher
Pankhurst T, Buick K, Lange J, Marshall A, Button K, Palmer O, et al. MAIT cells activate dendritic cells to promote TFH cell differentiation and induce humoral immunity. Cell Rep. 2023;42:112310 pubmed publisher
Koutn xed k J, Leitges M, Siegmund K. T cell-intrinsic protein kinase D3 is dispensable for the cells' activation. Front Immunol. 2022;13:1049033 pubmed publisher
Robles Valero J, Fern xe1 ndez Nevado L, Cuadrado M, Lorenzo Mart xed n L, Fern xe1 ndez Pisonero I, Abad A, et al. Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model. Mol Oncol. 2022;16:3533-3553 pubmed publisher
Zhang Y, Tan W, Lou Z, Zhao Y, Zhang J, Liang H, et al. Vaccination with Omicron Inactivated Vaccine in Pre-vaccinated Mice Protects against SARS-CoV-2 Prototype and Omicron Variants. Vaccines (Basel). 2022;10: pubmed publisher
Hu Q, Xu T, Zhang M, Zhang H, Liu Y, Li H, et al. Diverging regulation of Bach2 protein and RNA expression determine cell fate in early B cell response. Cell Rep. 2022;40:111035 pubmed publisher
Du J, Wang Q, Yang S, Chen S, Fu Y, Spath S, et al. FOXP3 exon 2 controls Treg stability and autoimmunity. Sci Immunol. 2022;7:eabo5407 pubmed publisher
Zhang Y, Tan W, Lou Z, Huang B, Zhou W, Zhao Y, et al. Immunogenicity Evaluating of the Multivalent COVID-19 Inactivated Vaccine against the SARS-CoV-2 Variants. Vaccines (Basel). 2022;10: pubmed publisher
Grenov A, Hezroni H, Lasman L, Hanna J, Shulman Z. YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation. Cell Rep. 2022;39:110778 pubmed publisher
Stienne C, Virgen Slane R, Elm xe9 n L, Veny M, Huang S, Nguyen J, et al. Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa. Cell Rep. 2022;38:110553 pubmed publisher
Shiozawa S, Tsumiyama K, Miyazaki Y, Uto K, Sakurai K, Nakashima T, et al. DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus. iScience. 2022;25:103537 pubmed publisher
Parthasarathy R, Hägglöf T, Hadley J, McLennan A, Mattke A, Dudley E, et al. Receptor Interacting Protein Kinase Pathways Regulate Innate B Cell Developmental Checkpoints But Not Effector Function in Mice. Front Immunol. 2021;12:758407 pubmed publisher
Stephens W, Kubinak J, Ghazaryan A, Bauer K, Bell R, Buhrke K, et al. Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition. Cell Rep. 2021;37:109916 pubmed publisher
Guo C, Peng Y, Lin L, Pan X, Fang M, Zhao Y, et al. A pathogen-like antigen-based vaccine confers immune protection against SARS-CoV-2 in non-human primates. Cell Rep Med. 2021;2:100448 pubmed publisher
Zhang Y, Paynter J, Sou C, Fourfouris T, Wang Y, Abraham C, et al. Mechanism of a COVID-19 nanoparticle vaccine candidate that elicits a broadly neutralizing antibody response to SARS-CoV-2 variants. Sci Adv. 2021;7:eabj3107 pubmed publisher
Robles Valero J, Fernandez Nevado L, Lorenzo Martín L, Cuadrado M, Fernández Pisonero I, Rodríguez Fdez S, et al. Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis. EMBO J. 2021;40:e108125 pubmed publisher
Duan L, Liu D, Chen H, Mintz M, Chou M, Kotov D, et al. Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation. Immunity. 2021;54:2256-2272.e6 pubmed publisher
Zhong C, Liu F, Hajnik R, Yao L, Chen K, Wang M, et al. Type I Interferon Promotes Humoral Immunity in Viral Vector Vaccination. J Virol. 2021;95:e0092521 pubmed publisher
Pack A, Schwartzhoff P, Zacharias Z, Fernández Ruiz D, Heath W, Gurung P, et al. Hemozoin-mediated inflammasome activation limits long-lived anti-malarial immunity. Cell Rep. 2021;36:109586 pubmed publisher
Tan J, Ni D, Wali J, Cox D, Pinget G, Taitz J, et al. Dietary carbohydrate, particularly glucose, drives B cell lymphopoiesis and function. iScience. 2021;24:102835 pubmed publisher
Delvecchio F, Fincham R, Spear S, Clear A, Roy Luzarraga M, Balkwill F, et al. Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice. Cell Mol Gastroenterol Hepatol. 2021;12:1543-1565 pubmed publisher
Super M, Doherty E, Cartwright M, Seiler B, Langellotto F, Dimitrakakis N, et al. Biomaterial vaccines capturing pathogen-associated molecular patterns protect against bacterial infections and septic shock. Nat Biomed Eng. 2021;: pubmed publisher
Volberding P, Xin G, Kasmani M, Khatun A, Brown A, Nguyen C, et al. Suppressive neutrophils require PIM1 for metabolic fitness and survival during chronic viral infection. Cell Rep. 2021;35:109160 pubmed publisher
Frost J, Tan T, Abbas M, Wideman S, Bonadonna M, Stoffel N, et al. Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to Vaccination and Infection. Med. 2021;2:164-179.e12 pubmed publisher
Crouse B, Robinson C, Huseby Kelcher A, Laudenbach M, Abrahante J, Pravetoni M. Mechanisms of interleukin 4 mediated increase in efficacy of vaccines against opioid use disorders. NPJ Vaccines. 2020;5:99 pubmed publisher
Wong R, Belk J, Govero J, Uhrlaub J, Reinartz D, Zhao H, et al. Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses. Immunity. 2020;53:1078-1094.e7 pubmed publisher
Bartleson J, Viehmann Milam A, Donermeyer D, Horvath S, Xia Y, Egawa T, et al. Strength of tonic T cell receptor signaling instructs T follicular helper cell-fate decisions. Nat Immunol. 2020;21:1384-1396 pubmed publisher
Nasrallah R, Imianowski C, Bossini Castillo L, Grant F, Dogan M, Placek L, et al. A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells. Nature. 2020;583:447-452 pubmed publisher
Yang D, Sun Y, Chen J, Zhang Y, Fan S, Huang M, et al. REV7 is required for processing AID initiated DNA lesions in activated B cells. Nat Commun. 2020;11:2812 pubmed publisher
Sisteré Oró M, Pedersen G, Cordoba L, López Serrano S, Christensen D, Darji A. Influenza NG-34 T cell conserved epitope adjuvanted with CAF01 as a possible influenza vaccine candidate. Vet Res. 2020;51:57 pubmed publisher
Yang C, Mogno I, Contijoch E, Borgerding J, Aggarwala V, Li Z, et al. Fecal IgA Levels Are Determined by Strain-Level Differences in Bacteroides ovatus and Are Modifiable by Gut Microbiota Manipulation. Cell Host Microbe. 2020;27:467-475.e6 pubmed publisher
Biram A, Winter E, Denton A, Zaretsky I, Dassa B, Bemark M, et al. B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer's Patches. Cell Rep. 2020;30:1910-1922.e5 pubmed publisher
Chen Z, Wholey W, Hassani Najafabadi A, Moon J, Grigorova I, Chackerian B, et al. Self-Antigens Displayed on Liposomal Nanoparticles above a Threshold of Epitope Density Elicit Class-Switched Autoreactive Antibodies Independent of T Cell Help. J Immunol. 2020;204:335-347 pubmed publisher
Andersen T, Huszthy P, Gopalakrishnan R, Jacobsen J, Fauskanger M, Tveita A, et al. Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules. NPJ Vaccines. 2019;4:9 pubmed publisher
Chen J, Li N, Yin Y, Zheng N, Min M, Lin B, et al. Methyltransferase Nsd2 Ensures Germinal Center Selection by Promoting Adhesive Interactions between B Cells and Follicular Dendritic Cells. Cell Rep. 2018;25:3393-3404.e6 pubmed publisher
Xia Y, Xie Y, Yu Z, Xiao H, Jiang G, Zhou X, et al. The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery. Cell. 2018;175:1059-1073.e21 pubmed publisher
Beloor J, Maes N, Ullah I, Uchil P, Jackson A, Fikrig E, et al. Small Interfering RNA-Mediated Control of Virus Replication in the CNS Is Therapeutic and Enables Natural Immunity to West Nile Virus. Cell Host Microbe. 2018;23:549-556.e3 pubmed publisher
Platteel A, Nieuwenhuizen N, Domaszewska T, Schurer S, Zedler U, Brinkmann V, et al. Efficacy Testing of H56 cDNA Tattoo Immunization against Tuberculosis in a Mouse Model. Front Immunol. 2017;8:1744 pubmed publisher
Perez Mazliah D, Nguyen M, Hosking C, McLaughlin S, Lewis M, Tumwine I, et al. Follicular Helper T Cells are Essential for the Elimination of Plasmodium Infection. EBioMedicine. 2017;24:216-230 pubmed publisher
Laidlaw B, Schmidt T, Green J, Allen C, Okada T, Cyster J. The Eph-related tyrosine kinase ligand Ephrin-B1 marks germinal center and memory precursor B cells. J Exp Med. 2017;214:639-649 pubmed publisher
Voigt A, Esfandiary L, Wanchoo A, Glenton P, Donate A, Craft W, et al. Sexual dimorphic function of IL-17 in salivary gland dysfunction of the C57BL/6.NOD-Aec1Aec2 model of Sjögren's syndrome. Sci Rep. 2016;6:38717 pubmed publisher
Tam H, Melo M, Kang M, Pelet J, Ruda V, Foley M, et al. Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination. Proc Natl Acad Sci U S A. 2016;113:E6639-E6648 pubmed
Matsushita N, Suzuki M, Ikebe E, Nagashima S, Inatome R, Asano K, et al. Regulation of B cell differentiation by the ubiquitin-binding protein TAX1BP1. Sci Rep. 2016;6:31266 pubmed publisher
Cooley L, El Shikh M, Li W, Keim R, Zhang Z, Strauss J, et al. Impaired immunological synapse in sperm associated antigen 6 (SPAG6) deficient mice. Sci Rep. 2016;6:25840 pubmed publisher
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product information
Antigen :
GL7
Apps. Abbrev. :
FC
Cat # :
144603
Clone :
GL7
Item :
FITC anti-MU/HU GL7 Antigen (T/B Cell Act. Marker)
Isotype :
Rat IgM, κ
Other Names :
Ly77, T and B cell activation marker
Size :
50 μg
Price (USD) :
90 USD
Reactivity :
Mouse, Human
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
FITC
Immunogen :
LPS activated DBA/J mouse B cells
Application Notes :
The GL7 antibody does not block the binding of CD22 with sulfated a2-6-sialyl-LacNAc.Cross-reactivity to ferret has been reported by a collaborator, but not verified in house.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA