product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Ultra-LEAF™ Purified anti-mouse CD172a (SIRPα)
catalog :
144038
quantity :
25 mg
price :
1408 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
P84
reactivity :
mouse
application :
neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, mass cytometry
more info or order :
citations: 5
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:200; loading ...; fig 2f
Moreira T, Mangani D, Cox L, Leibowitz J, Lobo E, Oliveira M, et al. PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis. Nat Commun. 2021;12:4907 pubmed publisher
  • mass cytometry; mouse; loading ...; fig 1a, 1c, s1
Leylek R, Alcántara Hernández M, Lanzar Z, Lüdtke A, Perez O, Reizis B, et al. Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population. Cell Rep. 2019;29:3736-3750.e8 pubmed publisher
Hayes B, Wang M, Zhu H, Phan S, Dooling L, Andrechak J, et al. Chromosomal instability induced in cancer can enhance macrophage-initiated immune responses that include anti-tumor IgG. elife. 2024;12: pubmed publisher
Zimarino C, MOODY W, Davidson S, Munir H, Shields J. Disruption of CD47-SIRPα signaling restores inflammatory function in tumor-associated myeloid-derived suppressor cells. iScience. 2024;27:109546 pubmed publisher
Reed J, Preston Hurlburt P, Philbrick W, Betancur G, Korah M, LUCAS C, et al. The receptor for advanced glycation endproducts (RAGE) modulates T cell signaling. PLoS ONE. 2020;15:e0236921 pubmed publisher
product information
Antigen :
CD172alpha
Apps. Abbrev. :
FC, IHC-F, IP, Block
Cat # :
144038
Clone :
P84
Item :
Ultra-LEAF™ Purified anti-mouse CD172a (SIRPα)
Isotype :
Rat IgG1, κ
Other Names :
SHPS-1, BIT, P84, PTPNS1, CD172 antigen-like family member A
Size :
25 mg
Price (USD) :
1408 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
ULEAF
Immunogen :
Mouse brain membrane protein
Application Notes :
Additional reported applications (for the relevant formats) include: blocking SIRPa interaction with CD47^4, in vivo blocking of dendritic cell migration^3, enhancing of macrophage phagocytosis^2,4, immunohistochemical staining of cerebellum frozen sections^1, immunoprecipitation^2,4, and spatial biology (IBEX)^5,6.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA