product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-mouse CD172a (SIRPα)
catalog :
144006
quantity :
100 μg
price :
203 USD
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
P84
reactivity :
human, mouse
application :
immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 2h
Findlay E, Currie A, Zhang A, Ovciarikova J, Young L, Stevens H, et al. Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy. Oncoimmunology. 2019;8:1608106 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s1
Yanagita T, Murata Y, Tanaka D, Motegi S, Arai E, Daniwijaya E, et al. Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy. JCI Insight. 2017;2:e89140 pubmed publisher
Ma X, Liang X, Li Y, Feng Q, Cheng K, Ma N, et al. Modular-designed engineered bacteria for precision tumor immunotherapy via spatiotemporal manipulation by magnetic field. Nat Commun. 2023;14:1606 pubmed publisher
Kedmi R, Najar T, Mesa K, Grayson A, Kroehling L, Hao Y, et al. A RORγt+ cell instructs gut microbiota-specific Treg cell differentiation. Nature. 2022;610:737-743 pubmed publisher
Sanchez Molina P, Almolda B, Gim xe9 nez Llort L, Gonz xe1 lez B, Castellano B. Chronic IL-10 overproduction disrupts microglia-neuron dialogue similar to aging, resulting in impaired hippocampal neurogenesis and spatial memory. Brain Behav Immun. 2022;101:231-245 pubmed publisher
Gozgit J, Vasbinder M, Abo R, Kunii K, Kuplast Barr K, Gui B, et al. PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity. Cancer Cell. 2021;39:1214-1226.e10 pubmed publisher
Freed Pastor W, Lambert L, Ely Z, Pattada N, Bhutkar A, Eng G, et al. The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer. Cancer Cell. 2021;: pubmed publisher
Marangoni F, Zhakyp A, Corsini M, Geels S, Carrizosa E, Thelen M, et al. Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop. Cell. 2021;184:3998-4015.e19 pubmed publisher
Ding X, Wang J, Huang M, Chen Z, Liu J, Zhang Q, et al. Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration. Nat Commun. 2021;12:2030 pubmed publisher
Wang X, Luo X, Chen C, Tang Y, Li L, Mo B, et al. The Ap-2α/Elk-1 axis regulates Sirpα-dependent tumor phagocytosis by tumor-associated macrophages in colorectal cancer. Signal Transduct Target Ther. 2020;5:35 pubmed publisher
Fujita K, Chakarov S, Kobayashi T, Sakamoto K, Voisin B, Duan K, et al. Cell-autonomous FLT3L shedding via ADAM10 mediates conventional dendritic cell development in mouse spleen. Proc Natl Acad Sci U S A. 2019;116:14714-14723 pubmed publisher
Ko K, Lee I, Kim G, Gu M, Kim H, Park B, et al. Changes in bursal B cells in chicken during embryonic development and early life after hatching. Sci Rep. 2018;8:16905 pubmed publisher
Gotoh K, Morisaki T, Setoyama D, Sasaki K, Yagi M, Igami K, et al. Mitochondrial p32/C1qbp Is a Critical Regulator of Dendritic Cell Metabolism and Maturation. Cell Rep. 2018;25:1800-1815.e4 pubmed publisher
Perry J, Russler Germain E, Zhou Y, Purtha W, Cooper M, Choi J, et al. Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-tolerance. Immunity. 2018;48:923-936.e4 pubmed publisher
Wu Y, Wu Y, Mo S, Hsiao H, He Y, Lai M. Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling. J Immunol. 2015;195:2612-23 pubmed publisher
product information
Antigen :
CD172alpha
Apps. Abbrev. :
FC, IHC-F
Cat # :
144006
Clone :
P84
Item :
FITC anti-mouse CD172a (SIRPα)
Isotype :
Rat IgG1, κ
Other Names :
SHPS-1, BIT, P84, PTPNS1, CD172 antigen-like family member A
Size :
100 μg
Price (USD) :
203 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
FITC
Immunogen :
Mouse brain membrane protein
Application Notes :
Additional reported applications (for the relevant formats) include: blocking SIRPa interaction with CD47^4, in vivo blocking of dendritic cell migration^3, enhancing of macrophage phagocytosis^2,4, immunohistochemical staining of cerebellum frozen sections^1, immunoprecipitation^2,4, and spatial biology (IBEX)^5,6.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA