Purified anti-mouse CD172a (SIRPα) | BioLegend 144001 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-mouse CD172a (SIRPα)

catalog :

144001

quantity :

50 μg

price :

112 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

P84

reactivity :

human, mouse

application :

immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, mass cytometry

more info or order :

BioLegend product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:200; loading ...; fig 2f	Moreira T, Mangani D, Cox L, Leibowitz J, Lobo E, Oliveira M, et al. PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis. Nat Commun. 2021;12:4907 pubmed publisher
mass cytometry; mouse; loading ...; fig 1a, 1c, s1	Leylek R, Alcántara Hernández M, Lanzar Z, Lüdtke A, Perez O, Reizis B, et al. Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population. Cell Rep. 2019;29:3736-3750.e8 pubmed publisher
flow cytometry; mouse; loading ...; fig s2a	Choi H, Suwanpradid J, Kim I, Staats H, Haniffa M, Macleod A, et al. Perivascular dendritic cells elicit anaphylaxis by relaying allergens to mast cells via microvesicles. Science. 2018;362: pubmed publisher
flow cytometry; mouse; loading ...; fig s1b	Herndler Brandstetter D, Shan L, Yao Y, Stecher C, Plajer V, Lietzenmayer M, et al. Humanized mouse model supports development, function, and tissue residency of human natural killer cells. Proc Natl Acad Sci U S A. 2017;114:E9626-E9634 pubmed publisher
immunocytochemistry; human; loading ...; fig s1	Yanagita T, Murata Y, Tanaka D, Motegi S, Arai E, Daniwijaya E, et al. Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy. JCI Insight. 2017;2:e89140 pubmed publisher
	Barvalia M, Harder K. An End-to-End Workflow for Interrogating Tumor-Infiltrating Myeloid Cells Using Mass Cytometry. Methods Mol Biol. 2022;2508:147-168 pubmed publisher
	Hutton C, Heider F, Blanco Gómez A, Banyard A, Kononov A, Zhang X, et al. Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity. Cancer Cell. 2021;: pubmed publisher
	Bajana S, Thomas K, Georgescu C, Zhao Y, Wren J, Kovats S, et al. Augmenting E Protein Activity Impairs cDC2 Differentiation at the Pre-cDC Stage. Front Immunol. 2020;11:577718 pubmed publisher
	Liu H, Wilson K, Schriek P, Macri C, Blum A, Francis L, et al. Ubiquitination of MHC Class II Is Required for Development of Regulatory but Not Conventional CD4+ T Cells. J Immunol. 2020;205:1207-1216 pubmed publisher
	Wang X, Luo X, Chen C, Tang Y, Li L, Mo B, et al. The Ap-2α/Elk-1 axis regulates Sirpα-dependent tumor phagocytosis by tumor-associated macrophages in colorectal cancer. Signal Transduct Target Ther. 2020;5:35 pubmed publisher
	Elgawidi A, Mohsin M, Ali F, Watts A, Monk P, Thomas M, et al. A role for tetraspanin proteins in regulating fusion induced by Burkholderia thailandensis. Med Microbiol Immunol. 2020;209:473-487 pubmed publisher
	Li J, Sarute N, Lancaster E, Otkiran Clare G, Fagla B, Ross S, et al. A recessive Trim2 mutation causes an axonal neuropathy in mice. Neurobiol Dis. 2020;140:104845 pubmed publisher
	Ko K, Lee I, Kim G, Gu M, Kim H, Park B, et al. Changes in bursal B cells in chicken during embryonic development and early life after hatching. Sci Rep. 2018;8:16905 pubmed publisher
	Gubin M, Esaulova E, Ward J, Malkova O, Runci D, Wong P, et al. High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy. Cell. 2018;175:1014-1030.e19 pubmed publisher
	Mrdjen D, Pavlovic A, Hartmann F, Schreiner B, Utz S, Leung B, et al. High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease. Immunity. 2018;48:380-395.e6 pubmed publisher

product information

Antigen :

CD172alpha

Apps. Abbrev. :

FC, IHC-F, IP, Block

Cat # :

144001

Clone :

P84

Item :

Purified anti-mouse CD172a (SIRPα)

Isotype :

Rat IgG1, κ

Other Names :

SHPS-1, BIT, P84, PTPNS1, CD172 antigen-like family member A

Size :

50 μg

Price (USD) :

112 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PURE

Immunogen :

Mouse brain membrane protein

Application Notes :

Additional reported applications (for the relevant formats) include: blocking SIRPa interaction with CD47^4, in vivo blocking of dendritic cell migration^3, enhancing of macrophage phagocytosis^2,4, immunohistochemical staining of cerebellum frozen sections^1, immunoprecipitation^2,4, and spatial biology (IBEX)^5,6.;

more info or order :

BioLegend product webpage