product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-mouse CD138 (Syndecan-1)
catalog :
142508
quantity :
500 μL
price :
402 USD
clonality :
monoclonal
host :
rat
conjugate :
BV421
clone name :
281-2
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 51
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s1
Mesin L, Schiepers A, Ersching J, Barbulescu A, Cavazzoni C, Angelini A, et al. Restricted Clonality and Limited Germinal Center Reentry Characterize Memory B Cell Reactivation by Boosting. Cell. 2020;180:92-106.e11 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5g
Moffett H, Harms C, Fitzpatrick K, Tooley M, Boonyaratanakornkit J, Taylor J. B cells engineered to express pathogen-specific antibodies protect against infection. Sci Immunol. 2019;4: pubmed publisher
  • flow cytometry; mouse; fig 3e
Graf R, Seagal J, Otipoby K, Lam K, Ayoub S, Zhang B, et al. BCR-dependent lineage plasticity in mature B cells. Science. 2019;363:748-753 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1b
Vuckovic S, Minnie S, Smith D, Gartlan K, Watkins T, Markey K, et al. Bone marrow transplantation generates T cell-dependent control of myeloma in mice. J Clin Invest. 2019;129:106-121 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b
Robak O, Heimesaat M, Kruglov A, Prepens S, Ninnemann J, Gutbier B, et al. Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia. J Clin Invest. 2018;128:3535-3545 pubmed publisher
  • flow cytometry; mouse; loading ...
Forster M, Farrington K, Petrov J, Belle J, Mindt B, Witalis M, et al. MYSM1-dependent checkpoints in B cell lineage differentiation and B cell-mediated immune response. J Leukoc Biol. 2017;101:643-654 pubmed publisher
Yazicioglu Y, Marin E, Sandhu C, Galiani S, Raza I, Ali M, et al. Dynamic mitochondrial transcription and translation in B cells control germinal center entry and lymphomagenesis. Nat Immunol. 2023;24:991-1006 pubmed publisher
Gon Y, Kandou T, Tsuruyama T, Iwasaki T, Kitagori K, Murakami K, et al. Increased number of T cells and exacerbated inflammatory pathophysiology in a human IgG4 knock-in MRL/lpr mouse model. PLoS ONE. 2023;18:e0279389 pubmed publisher
Daum P, Ottmann S, Meinzinger J, Schulz S, C xf4 rte Real J, Hauke M, et al. The microRNA processing subunit DGCR8 is required for a T cell-dependent germinal center response. Front Immunol. 2022;13:991347 pubmed publisher
Kraemer A, Sch xe4 fer A, Sprenger D, Sehnert B, Williams J, Luo A, et al. Impact of dietary vitamin D on immunoregulation and disease pathology in lupus-prone NZB/W F1 mice. Front Immunol. 2022;13:933191 pubmed publisher
Chen P, Katsuyama E, Satyam A, Li H, Rubio J, Jung S, et al. CD38 reduces mitochondrial fitness and cytotoxic T cell response against viral infection in lupus patients by suppressing mitophagy. Sci Adv. 2022;8:eabo4271 pubmed publisher
Kodali S, Li M, Budai M, Chen M, Wang J. Protection of Quiescence and Longevity of IgG Memory B Cells by Mitochondrial Autophagy. J Immunol. 2022;208:1085-1098 pubmed publisher
Cossarizza A, Chang H, Radbruch A, Abrignani S, Addo R, Akdis M, et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition). Eur J Immunol. 2021;51:2708-3145 pubmed publisher
Alameh M, Tombácz I, Bettini E, Lederer K, Sittplangkoon C, Wilmore J, et al. Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses. Immunity. 2021;54:2877-2892.e7 pubmed publisher
Li X, Zeng Q, Wang S, Li M, Chen X, Huang Y, et al. CRAC Channel Controls the Differentiation of Pathogenic B Cells in Lupus Nephritis. Front Immunol. 2021;12:779560 pubmed publisher
Trindade B, Ceglia S, Berthelette A, Raso F, Howley K, Muppidi J, et al. The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation. Immunity. 2021;54:2273-2287.e6 pubmed publisher
Duan L, Liu D, Chen H, Mintz M, Chou M, Kotov D, et al. Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation. Immunity. 2021;54:2256-2272.e6 pubmed publisher
Glaros V, Rauschmeier R, Artemov A, Reinhardt A, Ols S, Emmanouilidi A, et al. Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response. Immunity. 2021;54:2005-2023.e10 pubmed publisher
Nascimento D, Viacava P, Ferreira R, Damaceno M, Pi xf1 eros A, Melo P, et al. Sepsis expands a CD39+ plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity. Immunity. 2021;54:2024-2041.e8 pubmed publisher
Pack A, Schwartzhoff P, Zacharias Z, Fernández Ruiz D, Heath W, Gurung P, et al. Hemozoin-mediated inflammasome activation limits long-lived anti-malarial immunity. Cell Rep. 2021;36:109586 pubmed publisher
Mandal R, Denny J, Namazzi R, Opoka R, Datta D, John C, et al. Dynamic modulation of spleen germinal center reactions by gut bacteria during Plasmodium infection. Cell Rep. 2021;35:109094 pubmed publisher
Lazarian G, Yin S, ten Hacken E, Sewastianik T, Uduman M, Font Tello A, et al. A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation. Cancer Cell. 2021;39:380-393.e8 pubmed publisher
Frost J, Tan T, Abbas M, Wideman S, Bonadonna M, Stoffel N, et al. Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to Vaccination and Infection. Med. 2021;2:164-179.e12 pubmed publisher
Amend A, Wickli N, Schäfer A, Sprenger D, Manz R, Voll R, et al. Dual Role of Interleukin-10 in Murine NZB/W F1 Lupus. Int J Mol Sci. 2021;22: pubmed publisher
Rivas M, Meydan C, Chin C, Challman M, Kim D, Bhinder B, et al. Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation. Nat Immunol. 2021;22:240-253 pubmed publisher
Waide M, Polidoro R, Powell W, Denny J, Kos J, Tieri D, et al. Gut Microbiota Composition Modulates the Magnitude and Quality of Germinal Centers during Plasmodium Infections. Cell Rep. 2020;33:108503 pubmed publisher
Qi T, Sun M, Zhang C, Chen P, Xiao C, Chang X. Ascorbic Acid Promotes Plasma Cell Differentiation through Enhancing TET2/3-Mediated DNA Demethylation. Cell Rep. 2020;33:108452 pubmed publisher
Haniuda K, Fukao S, Kitamura D. Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling. Cell Rep. 2020;33:108333 pubmed publisher
Viant C, Weymar G, Escolano A, Chen S, Hartweger H, Cipolla M, et al. Antibody Affinity Shapes the Choice between Memory and Germinal Center B Cell Fates. Cell. 2020;183:1298-1311.e11 pubmed publisher
Baranek T, Lebrigand K, de Amat Herbozo C, Gonzalez L, Bogard G, Dietrich C, et al. High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision. Cell Rep. 2020;32:108116 pubmed publisher
Venturutti L, Teater M, Zhai A, Chadburn A, Babiker L, Kim D, et al. TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate. Cell. 2020;182:297-316.e27 pubmed publisher
Qi H, Tian D, Li M, Zhang C, Jin H, Liu L, et al. Foxo3 Promotes the Differentiation and Function of Follicular Helper T Cells. Cell Rep. 2020;31:107621 pubmed publisher
B guelin W, Teater M, Meydan C, Hoehn K, Phillip J, Soshnev A, et al. Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response. Cancer Cell. 2020;37:655-673.e11 pubmed publisher
Kunishita Y, Yoshimi R, Kamiyama R, Kishimoto D, Yoshida K, Hashimoto E, et al. TRIM21 Dysfunction Enhances Aberrant B-Cell Differentiation in Autoimmune Pathogenesis. Front Immunol. 2020;11:98 pubmed publisher
Krautler N, Yermanos A, Pedrioli A, Welten S, Lorgé D, Greczmiel U, et al. Quantitative and Qualitative Analysis of Humoral Immunity Reveals Continued and Personalized Evolution in Chronic Viral Infection. Cell Rep. 2020;30:997-1012.e6 pubmed publisher
Wang Y, Tsai D, Ko Y, Yang T, Lin I, Hung K, et al. Blimp-1 Contributes to the Development and Function of Regulatory B Cells. Front Immunol. 2019;10:1909 pubmed publisher
Vono M, Eberhardt C, Auderset F, Mastelic Gavillet B, Lemeille S, Christensen D, et al. Maternal Antibodies Inhibit Neonatal and Infant Responses to Vaccination by Shaping the Early-Life B Cell Repertoire within Germinal Centers. Cell Rep. 2019;28:1773-1784.e5 pubmed publisher
Mintz M, Felce J, Chou M, Mayya V, Xu Y, Shui J, et al. The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis. Immunity. 2019;: pubmed publisher
Schoeler K, Aufschnaiter A, Messner S, Derudder E, Herzog S, Villunger A, et al. TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells. FEBS J. 2019;286:3566-3581 pubmed publisher
Farsakoglu Y, Palomino Segura M, Latino I, Zanaga S, Chatziandreou N, Pizzagalli D, et al. Influenza Vaccination Induces NK-Cell-Mediated Type-II IFN Response that Regulates Humoral Immunity in an IL-6-Dependent Manner. Cell Rep. 2019;26:2307-2315.e5 pubmed publisher
Hatzi K, Geng H, Doane A, Meydan C, LaRiviere R, Cárdenas M, et al. Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis. Nat Immunol. 2019;20:86-96 pubmed publisher
Kenderes K, Levack R, Papillion A, Cabrera Martinez B, Dishaw L, Winslow G. T-Bet+ IgM Memory Cells Generate Multi-lineage Effector B Cells. Cell Rep. 2018;24:824-837.e3 pubmed publisher
Lino A, Dang V, Lampropoulou V, Welle A, Joedicke J, Pohar J, et al. LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells. Immunity. 2018;49:120-133.e9 pubmed publisher
Rodda L, Lu E, Bennett M, Sokol C, Wang X, Luther S, et al. Single-Cell RNA Sequencing of Lymph Node Stromal Cells Reveals Niche-Associated Heterogeneity. Immunity. 2018;48:1014-1028.e6 pubmed publisher
Ise W, Fujii K, Shiroguchi K, Ito A, Kometani K, Takeda K, et al. T Follicular Helper Cell-Germinal Center B Cell Interaction Strength Regulates Entry into Plasma Cell or Recycling Germinal Center Cell Fate. Immunity. 2018;48:702-715.e4 pubmed publisher
Reismann D, Stefanowski J, Gunther R, Rakhymzhan A, Matthys R, Nützi R, et al. Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature. Nat Commun. 2017;8:2153 pubmed publisher
Maschmeyer P, Petkau G, Siracusa F, Zimmermann J, Zügel F, Kühl A, et al. Selective targeting of pro-inflammatory Th1 cells by microRNA-148a-specific antagomirs in vivo. J Autoimmun. 2018;89:41-52 pubmed publisher
Scally S, McLeod B, Bosch A, Miura K, Liang Q, Carroll S, et al. Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun. 2017;8:1568 pubmed publisher
He Z, O Neal J, Wilson W, Mahajan N, Luo J, Wang Y, et al. Deletion of Rb1 induces both hyperproliferation and cell death in murine germinal center B cells. Exp Hematol. 2016;44:161-5.e4 pubmed publisher
Richardson E, Shukla S, Nagy N, Boom W, Beck R, Zhou L, et al. ERK Signaling Is Essential for Macrophage Development. PLoS ONE. 2015;10:e0140064 pubmed publisher
Huang L, Gebreselassie N, Gagliardo L, Ruyechan M, Luber K, Lee N, et al. Eosinophils mediate protective immunity against secondary nematode infection. J Immunol. 2015;194:283-90 pubmed publisher
product information
Antigen :
CD138
Apps. Abbrev. :
FC
Cat # :
142508
Clone :
281-2
Item :
Brilliant Violet 421™ anti-mouse CD138 (Syndecan-1)
Isotype :
Rat IgG2a, κ
Other Names :
Syndecan-1
Size :
500 μL
Price (USD) :
402 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
BV421
Immunogen :
Mouse mammary gland epithelial cell line NMuMG
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of frozen tissue^3 and formalin-fixed paraffin embedded tissue^4 and immunofluorescent staining^2,3.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA