product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse CD138 (Syndecan-1)
catalog :
142504
quantity :
200 μg
price :
351 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
281-2
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 56
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...
Zang M, Guo J, Liu L, Jin F, Feng X, An G, et al. Cdc37 suppression induces plasma cell immaturation and bortezomib resistance in multiple myeloma via Xbp1s. Oncogenesis. 2020;9:31 pubmed publisher
  • flow cytometry; mouse; 1:600; loading ...; fig 1s1b
Koike T, Harada K, Horiuchi S, Kitamura D. The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 5d
Sang A, Danhorn T, Peterson J, Rankin A, O Connor B, Leach S, et al. Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus. Nat Commun. 2018;9:3973 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2b
Liu J, Huang X, Hao S, Wang Y, Liu M, Xu J, et al. Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus. Nat Commun. 2018;9:1136 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4d
Tang C, Chang S, Paton A, Paton J, Gabrilovich D, Ploegh H, et al. Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization. J Cell Biol. 2018;217:1739-1755 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1d
Laidlaw B, Schmidt T, Green J, Allen C, Okada T, Cyster J. The Eph-related tyrosine kinase ligand Ephrin-B1 marks germinal center and memory precursor B cells. J Exp Med. 2017;214:639-649 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2c
Xue D, Desjardins M, Kaufman G, Beland M, Al Tamemi S, Ahmed E, et al. Semaphorin 4C: A Novel Component of B-Cell Polarization in Th2-Driven Immune Responses. Front Immunol. 2016;7:558 pubmed publisher
  • flow cytometry; mouse
Kim Y, Lim H, Jung H, Wetsel R, Chung Y. Regulation of autoimmune germinal center reactions in lupus-prone BXD2 mice by follicular helper T cells. PLoS ONE. 2015;10:e0120294 pubmed publisher
Kuang C, Xia M, An G, Liu C, Hu C, Zhang J, et al. Excessive serine from the bone marrow microenvironment impairs megakaryopoiesis and thrombopoiesis in Multiple Myeloma. Nat Commun. 2023;14:2093 pubmed publisher
Voss L, Howarth A, Wittenborn T, Hummelgaard S, Juul Madsen K, Kastberg K, et al. The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus. Front Immunol. 2022;13:1021370 pubmed publisher
Tu X, Chu T, Jeltema D, Abbott K, Yang K, Xing C, et al. Interruption of post-Golgi STING trafficking activates tonic interferon signaling. Nat Commun. 2022;13:6977 pubmed publisher
Chen H, Almonte Loya A, Lay F, Hsu M, Johnson E, Gonz xe1 lez Avalos E, et al. Epigenetic remodeling by vitamin C potentiates plasma cell differentiation. elife. 2022;11: pubmed publisher
Gregoire C, Spinelli L, Villazala Merino S, Gil L, Holgado M, Moussa M, et al. Viral infection engenders bona fide and bystander subsets of lung-resident memory B cells through a permissive mechanism. Immunity. 2022;55:1216-1233.e9 pubmed publisher
Pandey S, Bender M, McPherson A, Phelps C, Sanchez L, Rana M, et al. Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis. Cell Host Microbe. 2022;30:1003-1019.e10 pubmed publisher
Song W, Antao O, Condiff E, Sanchez G, Chernova I, Zembrzuski K, et al. Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centers. Immunity. 2022;55:290-307.e5 pubmed publisher
Shiozawa S, Tsumiyama K, Miyazaki Y, Uto K, Sakurai K, Nakashima T, et al. DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus. iScience. 2022;25:103537 pubmed publisher
Wang J, Cao Z, Wang P, Zhang X, Tang J, He Y, et al. Apoptotic Extracellular Vesicles Ameliorate Multiple Myeloma by Restoring Fas-Mediated Apoptosis. ACS Nano. 2021;15:14360-14372 pubmed publisher
Szodoray P, Andersen T, Heinzelbecker J, Imbery J, Huszthy P, Stanford S, et al. Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity. Cell Rep. 2021;36:109525 pubmed publisher
Jütte B, Krollmann C, Cieslak K, Koerber R, Boor P, Graef C, et al. Intercellular cGAMP transmission induces innate immune activation and tissue inflammation in Trex1 deficiency. iScience. 2021;24:102833 pubmed publisher
Zheng B, Peng W, Gan L, Guo M, Wang S, Zhang X, et al. Sendai virus-based immunoadjuvant in hydrogel vaccine intensity-modulated dendritic cells activation for suppressing tumorigenesis. Bioact Mater. 2021;6:3879-3891 pubmed publisher
Che N, Sun X, Gu L, Wang X, Shi J, Sun Y, et al. Adiponectin Enhances B-Cell Proliferation and Differentiation via Activation of Akt1/STAT3 and Exacerbates Collagen-Induced Arthritis. Front Immunol. 2021;12:626310 pubmed publisher
Frost J, Tan T, Abbas M, Wideman S, Bonadonna M, Stoffel N, et al. Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to Vaccination and Infection. Med. 2021;2:164-179.e12 pubmed publisher
Yang Y, Li X, Ma Z, Wang C, Yang Q, Byrne Steele M, et al. CTLA-4 expression by B-1a B cells is essential for immune tolerance. Nat Commun. 2021;12:525 pubmed publisher
Qi T, Sun M, Zhang C, Chen P, Xiao C, Chang X. Ascorbic Acid Promotes Plasma Cell Differentiation through Enhancing TET2/3-Mediated DNA Demethylation. Cell Rep. 2020;33:108452 pubmed publisher
Huang D, Tran J, Olson A, Vollbrecht T, Tenuta M, Guryleva M, et al. Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells. Nat Commun. 2020;11:5850 pubmed publisher
Haniuda K, Fukao S, Kitamura D. Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling. Cell Rep. 2020;33:108333 pubmed publisher
Simoni L, Presumey J, van der Poel C, Castrillón C, Chang S, Utz P, et al. Complement C4A Regulates Autoreactive B Cells in Murine Lupus. Cell Rep. 2020;33:108330 pubmed publisher
Klessing S, Temchura V, Tannig P, Peter A, Christensen D, Lang R, et al. CD4+ T Cells Induced by Tuberculosis Subunit Vaccine H1 Can Improve the HIV-1 Env Humoral Response by Intrastructural Help. Vaccines (Basel). 2020;8: pubmed publisher
Wong R, Belk J, Govero J, Uhrlaub J, Reinartz D, Zhao H, et al. Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses. Immunity. 2020;53:1078-1094.e7 pubmed publisher
Steinmetz T, Schlötzer Schrehardt U, Hearne A, Schuh W, Wittner J, Schulz S, et al. TFG is required for autophagy flux and to prevent endoplasmic reticulum stress in CH12 B lymphoma cells. Autophagy. 2020;:1-19 pubmed publisher
Baranek T, Lebrigand K, de Amat Herbozo C, Gonzalez L, Bogard G, Dietrich C, et al. High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision. Cell Rep. 2020;32:108116 pubmed publisher
Li H, Limenitakis J, Greiff V, Yilmaz B, Schären O, Urbaniak C, et al. Mucosal or systemic microbiota exposures shape the B cell repertoire. Nature. 2020;584:274-278 pubmed publisher
Utley A, Chavel C, Lightman S, Holling G, Cooper J, Peng P, et al. CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival. Cell Rep. 2020;31:107815 pubmed publisher
Pan H, Steixner Kumar A, Seelbach A, Deutsch N, Ronnenberg A, Tapken D, et al. Multiple inducers and novel roles of autoantibodies against the obligatory NMDAR subunit NR1: a translational study from chronic life stress to brain injury. Mol Psychiatry. 2021;26:2471-2482 pubmed publisher
Krautler N, Yermanos A, Pedrioli A, Welten S, Lorgé D, Greczmiel U, et al. Quantitative and Qualitative Analysis of Humoral Immunity Reveals Continued and Personalized Evolution in Chronic Viral Infection. Cell Rep. 2020;30:997-1012.e6 pubmed publisher
Elsner R, Shlomchik M. IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression. Cell Rep. 2019;29:2796-2809.e5 pubmed publisher
van der Poel C, Bajic G, Macaulay C, van den Broek T, Ellson C, Bouma G, et al. Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcγRIIB. Cell Rep. 2019;29:2745-2755.e4 pubmed publisher
Olson W, Jakic B, Labi V, Schoeler K, Kind M, Klepsch V, et al. Orphan Nuclear Receptor NR2F6 Suppresses T Follicular Helper Cell Accumulation through Regulation of IL-21. Cell Rep. 2019;28:2878-2891.e5 pubmed publisher
Schoeler K, Aufschnaiter A, Messner S, Derudder E, Herzog S, Villunger A, et al. TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells. FEBS J. 2019;286:3566-3581 pubmed publisher
Roy K, Mitchell S, Liu Y, Ohta S, Lin Y, Metzig M, et al. A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell Differentiation. Immunity. 2019;50:616-628.e6 pubmed publisher
Chen J, Li N, Yin Y, Zheng N, Min M, Lin B, et al. Methyltransferase Nsd2 Ensures Germinal Center Selection by Promoting Adhesive Interactions between B Cells and Follicular Dendritic Cells. Cell Rep. 2018;25:3393-3404.e6 pubmed publisher
Wang L, Kumar M, Deng Q, Wang X, Liu M, Gong Z, et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces peripheral blood abnormalities and plasma cell neoplasms resembling multiple myeloma in mice. Cancer Lett. 2019;440-441:135-144 pubmed publisher
Firl D, Degn S, PADERA T, Carroll M. Capturing change in clonal composition amongst single mouse germinal centers. elife. 2018;7: pubmed publisher
Cho S, Lee H, Yu I, Choi Y, Huang H, Hashemifar S, et al. Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b. Nat Commun. 2018;9:2757 pubmed publisher
Ribeiro de Almeida C, Dhir S, Dhir A, Moghaddam A, Sattentau Q, Meinhart A, et al. RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination. Mol Cell. 2018;70:650-662.e8 pubmed publisher
Nakamura K, Kassem S, Cleynen A, Chrétien M, Guillerey C, Putz E, et al. Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment. Cancer Cell. 2018;33:634-648.e5 pubmed publisher
Noviski M, Mueller J, SATTERTHWAITE A, Garrett Sinha L, Brombacher F, Zikherman J. IgM and IgD B cell receptors differentially respond to endogenous antigens and control B cell fate. elife. 2018;7: pubmed publisher
Schager A, Dominguez Medina C, Necchi F, Micoli F, Goh Y, Goodall M, et al. IgG Responses to Porins and Lipopolysaccharide within an Outer Membrane-Based Vaccine against Nontyphoidal Salmonella Develop at Discordant Rates. MBio. 2018;9: pubmed publisher
Liao T, Xue Y, Zhao D, Li S, Liu M, Chen J, et al. In Vivo Attenuation of Antibody-Mediated Acute Renal Allograft Rejection by Ex Vivo TGF-?-Induced CD4+Foxp3+ Regulatory T Cells. Front Immunol. 2017;8:1334 pubmed publisher
Degn S, van der Poel C, Firl D, Ayoglu B, Al Qureshah F, Bajic G, et al. Clonal Evolution of Autoreactive Germinal Centers. Cell. 2017;170:913-926.e19 pubmed publisher
Murphy M, Pattabiraman G, Manavalan T, Medvedev A. Deficiency in IRAK4 activity attenuates manifestations of murine Lupus. Eur J Immunol. 2017;47:880-891 pubmed publisher
Jash A, Wang Y, Weisel F, Scharer C, Boss J, Shlomchik M, et al. ZBTB32 Restricts the Duration of Memory B Cell Recall Responses. J Immunol. 2016;197:1159-68 pubmed publisher
Cook K, Shpargel K, Starmer J, Whitfield Larry F, Conley B, Allard D, et al. T Follicular Helper Cell-Dependent Clearance of a Persistent Virus Infection Requires T Cell Expression of the Histone Demethylase UTX. Immunity. 2015;43:703-14 pubmed publisher
Morse M, Clark K, Cascalho M, Kahlenberg J. Caspase-1 is required for maintenance of marginal zone B cells in pristane-induced lupus. Lupus. 2016;25:81-7 pubmed publisher
Clark K, Reed T, Wolf S, Lowe L, Hodgin J, Kahlenberg J. Epidermal injury promotes nephritis flare in lupus-prone mice. J Autoimmun. 2015;65:38-48 pubmed publisher
Chen M, Kodali S, Jang A, Kuai L, Wang J. Requirement for autophagy in the long-term persistence but not initial formation of memory B cells. J Immunol. 2015;194:2607-15 pubmed publisher
product information
Antigen :
CD138
Apps. Abbrev. :
FC
Cat # :
142504
Clone :
281-2
Item :
PE anti-mouse CD138 (Syndecan-1)
Isotype :
Rat IgG2a, κ
Other Names :
Syndecan-1
Size :
200 μg
Price (USD) :
351 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PE
Immunogen :
Mouse mammary gland epithelial cell line NMuMG
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of frozen tissue^3 and formalin-fixed paraffin embedded tissue^4 and immunofluorescent staining^2,3.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA