product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 594 anti-mouse CD169 (Siglec-1)
catalog :
142416
quantity :
100 μg
price :
382 USD
clonality :
monoclonal
host :
rat
conjugate :
Alexa Fluor 594
clone name :
3D6.112
reactivity :
mouse
application :
immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 23
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:150; fig 6e
Dagkonaki A, Papalambrou A, Avloniti M, Gkika A, Evangelidou M, Androutsou M, et al. Maturation of circulating Ly6ChiCCR2+ monocytes by mannan-MOG induces antigen-specific tolerance and reverses autoimmune encephalomyelitis. Front Immunol. 2022;13:972003 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 7c
Lin X, Twelkmeyer T, Zhu D, Zhang L, Zhao Y, Zhang C, et al. Homeostatic regulation of T follicular helper and antibody response to particle antigens by IL-1Ra of medullary sinus macrophage origin. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 4f
Martens R, Permanyer M, Werth K, Yu K, Braun A, Halle O, et al. Efficient homing of T cells via afferent lymphatics requires mechanical arrest and integrin-supported chemokine guidance. Nat Commun. 2020;11:1114 pubmed publisher
  • flow cytometry; mouse; loading ...; fig e6b
Solis A, Bielecki P, Steach H, Sharma L, Harman C, Yun S, et al. Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity. Nature. 2019;573:69-74 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Zhang J, Supakorndej T, Krambs J, Rao M, Abou Ezzi G, Ye R, et al. Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking. J Clin Invest. 2019;129:2920-2931 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1c
Cao A, Alluqmani N, Buhari F, Wasim L, Smith L, Quaile A, et al. Galectin-9 binds IgM-BCR to regulate B cell signaling. Nat Commun. 2018;9:3288 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 5c
Yanagihashi Y, Segawa K, Maeda R, Nabeshima Y, Nagata S. Mouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosis. Proc Natl Acad Sci U S A. 2017;114:8800-8805 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 5b
Turner V, Mabbott N. Structural and functional changes to lymph nodes in ageing mice. Immunology. 2017;151:239-247 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2a
Le Gars M, Haustant M, Klezovich Bénard M, Paget C, Trottein F, Goossens P, et al. Mechanisms of Invariant NKT Cell Activity in Restraining Bacillus anthracis Systemic Dissemination. J Immunol. 2016;197:3225-3232 pubmed
Bourges C, Groff A, Burren O, Gerhardinger C, Mattioli K, Hutchinson A, et al. Resolving mechanisms of immune-mediated disease in primary CD4 T cells. EMBO Mol Med. 2020;12:e12112 pubmed publisher
Lu Y, Zhao Q, Liao J, Song E, Xia Q, Pan J, et al. Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity. Cell. 2020;180:1081-1097.e24 pubmed publisher
Park C, Kehrl J. An integrin/MFG-E8 shuttle loads HIV-1 viral-like particles onto follicular dendritic cells in mouse lymph node. elife. 2019;8: pubmed publisher
Sun B, Yang D, Dai H, Liu X, Jia R, Cui X, et al. Eradication of Hepatocellular Carcinoma by NKG2D-Based CAR-T Cells. Cancer Immunol Res. 2019;7:1813-1823 pubmed publisher
Uderhardt S, Martins A, Tsang J, Lämmermann T, Germain R. Resident Macrophages Cloak Tissue Microlesions to Prevent Neutrophil-Driven Inflammatory Damage. Cell. 2019;177:541-555.e17 pubmed publisher
Blecher Gonen R, Bost P, Hilligan K, David E, Salame T, Roussel E, et al. Single-Cell Analysis of Diverse Pathogen Responses Defines a Molecular Roadmap for Generating Antigen-Specific Immunity. Cell Syst. 2019;8:109-121.e6 pubmed publisher
Uchil P, Pi R, Haugh K, Ladinsky M, Ventura J, Barrett B, et al. A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus. Cell Host Microbe. 2019;25:87-100.e10 pubmed publisher
Seydoux E, Liang H, Dubois Cauwelaert N, Archer M, Rintala N, Kramer R, et al. Effective Combination Adjuvants Engage Both TLR and Inflammasome Pathways To Promote Potent Adaptive Immune Responses. J Immunol. 2018;201:98-112 pubmed publisher
Vaartjes D, Nandakumar K, Holmdahl R, Raposo B. Increased salt exposure affects both lymphoid and myeloid effector functions, influencing innate-associated disease but not T-cell-associated autoimmunity. Immunology. 2018;: pubmed publisher
Wu X, Dayanand K, Thylur R, Norbury C, Gowda D. Small molecule-based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes. J Biol Chem. 2017;292:13615-13634 pubmed publisher
Deniset J, Surewaard B, Lee W, Kubes P. Splenic Ly6Ghigh mature and Ly6Gint immature neutrophils contribute to eradication of S. pneumoniae. J Exp Med. 2017;214:1333-1350 pubmed publisher
Sung S, Ge Y, Dai C, Wang H, Fu S, Sharma R, et al. Dependence of Glomerulonephritis Induction on Novel Intraglomerular Alternatively Activated Bone Marrow-Derived Macrophages and Mac-1 and PD-L1 in Lupus-Prone NZM2328 Mice. J Immunol. 2017;198:2589-2601 pubmed publisher
Ramos Perez W, Fang V, Escalante Alcalde D, Cammer M, Schwab S. A map of the distribution of sphingosine 1-phosphate in the spleen. Nat Immunol. 2015;16:1245-52 pubmed publisher
Klaas M, Oetke C, Lewis L, Erwig L, Heikema A, Easton A, et al. Sialoadhesin promotes rapid proinflammatory and type I IFN responses to a sialylated pathogen, Campylobacter jejuni. J Immunol. 2012;189:2414-22 pubmed publisher
product information
Antigen :
CD169
Apps. Abbrev. :
IHC-F, 3D IHC
Cat # :
142416
Clone :
3D6.112
Item :
Alexa Fluor® 594 anti-mouse CD169 (Siglec-1)
Isotype :
Rat IgG2a, κ
Other Names :
Sialic acid binding Ig-like lectin 1 (Siglec-1), Sialoadhesin (Sn)
Size :
100 μg
Price (USD) :
382 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
A594
Immunogen :
Purified Native Sialoadhesin from spleen
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining in frozen tissue sections 1 , and spatial biology (IBEX) 4,5 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA