product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-mouse CD206 (MMR)
catalog :
141717
quantity :
125 μL
price :
204 USD
clonality :
monoclonal
host :
rat
conjugate :
BV421
clone name :
C068C2
reactivity :
human, mouse
application :
immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 36
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:25; loading ...
Yang P, Qin H, Li Y, Xiao A, Zheng E, Zeng H, et al. CD36-mediated metabolic crosstalk between tumor cells and macrophages affects liver metastasis. Nat Commun. 2022;13:5782 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 2a
Nordlohne J, Hulsmann I, Schwafertz S, Zgrajek J, Grundmann M, von Vietinghoff S, et al. A flow cytometry approach reveals heterogeneity in conventional subsets of murine renal mononuclear phagocytes. Sci Rep. 2021;11:13251 pubmed publisher
  • flow cytometry; mouse; 1:130; loading ...; fig 3a
Glausen T, Carrillo G, Jin R, Boyle J, Saeij J, Wohlfert E, et al. The Toxoplasma Polymorphic Effector GRA15 Mediates Seizure Induction by Modulating Interleukin-1 Signaling in the Brain. MBio. 2021;12:e0133121 pubmed publisher
  • flow cytometry; human; loading ...
Zhou J, Pei X, Yang Y, Wang Z, Gao W, Ye R, et al. Orphan nuclear receptor TLX promotes immunosuppression via its transcriptional activation of PD-L1 in glioma. J Immunother Cancer. 2021;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1b
Macdougall C, Wood E, Loschko J, Scagliotti V, Cassidy F, Robinson M, et al. Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets. Cell Metab. 2018;27:588-601.e4 pubmed publisher
Brigo N, Neumaier E, Pfeifhofer Obermair C, Grubwieser P, Engl S, Berger S, et al. Timing of Interleukin-4 Stimulation of Macrophages Determines Their Anti-Microbial Activity during Infection with Salmonella enterica Serovar Typhimurium. Cells. 2023;12: pubmed publisher
Yu Y, Liu Y, Li Y, Yang X, Han M, Fan Q. Construction of a CCL20-centered circadian-signature based prognostic model in cervical cancer. Cancer Cell Int. 2023;23:92 pubmed publisher
Stratoulias V, Ruiz R, Kanatani S, Osman A, Keane L, Armengol J, et al. ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain. Nat Neurosci. 2023;26:1008-1020 pubmed publisher
Hattori Y, Kato D, Murayama F, Koike S, Asai H, Yamasaki A, et al. CD206+ macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia. Cell Rep. 2023;42:112092 pubmed publisher
Lu L, Zi H, Zhou J, Huang J, Deng Z, Tang Z, et al. Engineered Microparticles for Treatment of Murine Brain Metastasis by Reprograming Tumor Microenvironment and Inhibiting MAPK Pathway. Adv Sci (Weinh). 2023;10:e2206212 pubmed publisher
Liu M, Liu J, Liang Z, Dai K, Gan J, Wang Q, et al. CAR-Macrophages and CAR-T Cells Synergistically Kill Tumor Cells In Vitro. Cells. 2022;11: pubmed publisher
Kim S, Doherty C, Moghe M, Rait A, Pirollo K, Harford J, et al. Nanomedicine-Based Gene Delivery for a Truncated Tumor Suppressor RB94 Promotes Lung Cancer Immunity. Cancers (Basel). 2022;14: pubmed publisher
Gonzalez C, CIMINI M, Cheng Z, Benedict C, Wang C, Trungcao M, et al. Role of circular RNA cdr1as in modulation of macrophage phenotype. Life Sci. 2022;309:121003 pubmed publisher
Cho Y, Yoon Y, Im H, Son Y, Kim M, Saha A, et al. Adipocyte lysoplasmalogenase TMEM86A regulates plasmalogen homeostasis and protein kinase A-dependent energy metabolism. Nat Commun. 2022;13:4084 pubmed publisher
G xf3 mez Salinero J, Izzo F, Lin Y, Houghton S, Itkin T, Geng F, et al. Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction. Cell Stem Cell. 2022;29:593-609.e7 pubmed publisher
Ma Y, Fan P, Zhao R, Zhang Y, Wang X, Cui W. Neuregulin-1 regulates the conversion of M1/M2 microglia phenotype via ErbB4-dependent inhibition of the NF-κB pathway. Mol Biol Rep. 2022;49:3975-3986 pubmed publisher
Xiao Y, Chen J, Zhou H, Zeng X, Ruan Z, Pu Z, et al. Combining p53 mRNA nanotherapy with immune checkpoint blockade reprograms the immune microenvironment for effective cancer therapy. Nat Commun. 2022;13:758 pubmed publisher
Hanasoge Somasundara A, Moss M, Feigman M, Chen C, Cyrill S, Ciccone M, et al. Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis. Cell Rep. 2021;37:110099 pubmed publisher
Trofimova O, Korotkaja K, Skrastina D, Jansons J, Spunde K, Isaguliants M, et al. Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model. Vaccines (Basel). 2021;9: pubmed publisher
Conforti A, Wahlers T, Paunel Görgülü A. Neutrophil extracellular traps modulate inflammatory markers and uptake of oxidized LDL by human and murine macrophages. PLoS ONE. 2021;16:e0259894 pubmed publisher
Vicario N, Spitale F, Tibullo D, Giallongo C, Amorini A, Scandura G, et al. Clobetasol promotes neuromuscular plasticity in mice after motoneuronal loss via sonic hedgehog signaling, immunomodulation and metabolic rebalancing. Cell Death Dis. 2021;12:625 pubmed publisher
Giampazolias E, Schulz O, Lim K, Rogers N, Chakravarty P, Srinivasan N, et al. Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity. Cell. 2021;184:4016-4031.e22 pubmed publisher
Yang N, Ji F, Cheng L, Lu J, Sun X, Lin X, et al. Knockout of immunotherapy prognostic marker genes eliminates the effect of the anti-PD-1 treatment. NPJ Precis Oncol. 2021;5:37 pubmed publisher
Parigiani M, Ketscher A, Timme S, Bronsert P, Schlimpert M, Kammerer B, et al. Conditional Gene Targeting Reveals Cell Type-Specific Roles of the Lysosomal Protease Cathepsin L in Mammary Tumor Progression. Cancers (Basel). 2020;12: pubmed publisher
Alam Z, Devalaraja S, Li M, To T, Folkert I, Mitchell Velasquez E, et al. Counter Regulation of Spic by NF-κB and STAT Signaling Controls Inflammation and Iron Metabolism in Macrophages. Cell Rep. 2020;31:107825 pubmed publisher
Baumann D, Hägele T, Mochayedi J, Drebant J, Vent C, Blobner S, et al. Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy. Nat Commun. 2020;11:2176 pubmed publisher
Fulham M, Ratna A, Gerstein R, Kurt Jones E, Mandrekar P. Alcohol-induced adipose tissue macrophage phenotypic switching is independent of myeloid Toll-like receptor 4 expression. Am J Physiol Cell Physiol. 2019;317:C687-C700 pubmed publisher
Nguyen C, Tartar D, Bagood M, So M, Nguyen A, Gallegos A, et al. Topical Fluoxetine as a Novel Therapeutic That Improves Wound Healing in Diabetic Mice. Diabetes. 2019;68:1499-1507 pubmed publisher
Ayoub M, Shinde Jadhav S, Mansure J, Alvarez F, Connell T, Seuntjens J, et al. The immune mediated role of extracellular HMGB1 in a heterotopic model of bladder cancer radioresistance. Sci Rep. 2019;9:6348 pubmed publisher
Das L, Binko A, Traylor Z, Peng H, Lu K. Vitamin D improves sunburns by increasing autophagy in M2 macrophages. Autophagy. 2019;15:813-826 pubmed publisher
Simonneau M, Frouin E, Huguier V, Jermidi C, Jégou J, Godet J, et al. Oncostatin M is overexpressed in skin squamous-cell carcinoma and promotes tumor progression. Oncotarget. 2018;9:36457-36473 pubmed publisher
Kimbrough D, Wang S, Wright L, Mani S, Kasiganesan H, LaRue A, et al. HDAC inhibition helps post-MI healing by modulating macrophage polarization. J Mol Cell Cardiol. 2018;119:51-63 pubmed publisher
Chmielewski M, Abken H. CAR T Cells Releasing IL-18 Convert to T-Bethigh FoxO1low Effectors that Exhibit Augmented Activity against Advanced Solid Tumors. Cell Rep. 2017;21:3205-3219 pubmed publisher
Ito F, Ku A, Bucsek M, Muhitch J, Vardam Kaur T, Kim M, et al. Immune Adjuvant Activity of Pre-Resectional Radiofrequency Ablation Protects against Local and Systemic Recurrence in Aggressive Murine Colorectal Cancer. PLoS ONE. 2015;10:e0143370 pubmed publisher
Ito H, Yan X, Nagata N, Aritake K, Katsumata Y, Matsuhashi T, et al. PGD2-CRTH2 pathway promotes tubulointerstitial fibrosis. J Am Soc Nephrol. 2012;23:1797-809 pubmed publisher
Keller J, Catala Lehnen P, Wintges K, Schulze J, Bickert T, Ito W, et al. Transgenic over-expression of interleukin-33 in osteoblasts results in decreased osteoclastogenesis. Biochem Biophys Res Commun. 2012;417:217-22 pubmed publisher
product information
Antigen :
CD206
Apps. Abbrev. :
ICFC, FC, IHC-F, SB
Cat # :
141717
Clone :
C068C2
Item :
Brilliant Violet 421™ anti-mouse CD206 (MMR)
Isotype :
Rat IgG2a, κ
Other Names :
MMR (macrophage mannose receptor), MR (mannose receptor), MRC1
Size :
125 μL
Price (USD) :
204 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
BV421
Immunogen :
Recombinant mouse CD206 (MMR)
Application Notes :
Clone C068C2 recognizes a region similar to clone MR5D3, based on the ability of the clones to block each other. Additional reported applications (for the relevant formats) include: spatial biology (IBEX)^4,5.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA