product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 647 anti-mouse CD206 (MMR)
catalog :
141712
quantity :
100 μg
price :
293 USD
clonality :
monoclonal
host :
rat
conjugate :
AF647
clone name :
C068C2
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 135
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:100; loading ...; fig 1c
Beider K, Voevoda Dimenshtein V, Zoabi A, Rosenberg E, Magen H, Ostrovsky O, et al. CXCL13 chemokine is a novel player in multiple myeloma osteolytic microenvironment, M2 macrophage polarization, and tumor progression. J Hematol Oncol. 2022;15:144 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 5 ug/ml; loading ...; fig 2a
El Naccache D, Chen F, Palma M, Lemenze A, Fischer M, Wu W, et al. Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A2BAR signaling in intestinal epithelial cells. Cell Rep. 2022;40:111150 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1c
Kawakubo A, Miyagi M, Yokozeki Y, Nakawaki M, Takano S, Satoh M, et al. Origin of M2 Mϕ and its macrophage polarization by TGF-β in a mice intervertebral injury model. Int J Immunopathol Pharmacol. 2022;36:3946320221103792 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4c, s2b
Pan C, Wu Q, Wang S, Mei Z, Zhang L, Gao X, et al. Combination with Toll-like receptor 4 (TLR4) agonist reverses GITR agonism mediated M2 polarization of macrophage in Hepatocellular carcinoma. Oncoimmunology. 2022;11:2073010 pubmed publisher
  • flow cytometry; mouse; fig 2f
Larue M, Parker S, Puccini J, Cammer M, Kimmelman A, Bar Sagi D. Metabolic reprogramming of tumor-associated macrophages by collagen turnover promotes fibrosis in pancreatic cancer. Proc Natl Acad Sci U S A. 2022;119:e2119168119 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig s5d
Chen K, Hu Q, Xie Z, Yang G. Monocyte NLRP3-IL-1β Hyperactivation Mediates Neuronal and Synaptic Dysfunction in Perioperative Neurocognitive Disorder. Adv Sci (Weinh). 2022;9:e2104106 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3f
Bhattacharjee O, Ayyangar U, Kurbet A, Lakshmanan V, Palakodeti D, Ginhoux F, et al. Epithelial-Macrophage Crosstalk Initiates Sterile Inflammation in Embryonic Skin. Front Immunol. 2021;12:718005 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s3b
Yang C, Lei L, Collins J, Briones M, Ma L, Sturdevant G, et al. Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor. Nat Commun. 2021;12:5454 pubmed publisher
  • flow cytometry; mouse; loading ...
Forman R, Logunova L, Smith H, Wemyss K, Mair I, Boon L, et al. Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELMα+ macrophages. PLoS Pathog. 2021;17:e1009768 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2c
Gao D, Salomonis N, Henderlight M, Woods C, Thakkar K, Grom A, et al. IFN-γ is essential for alveolar macrophage-driven pulmonary inflammation in macrophage activation syndrome. JCI Insight. 2021;6: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5g
Mathä L, Romera Hernandez M, Steer C, Yin Y, Orangi M, Shim H, et al. Migration of Lung Resident Group 2 Innate Lymphoid Cells Link Allergic Lung Inflammation and Liver Immunity. Front Immunol. 2021;12:679509 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...
Van De Velde L, Allen E, Crawford J, Wilson T, Guy C, Russier M, et al. Neuroblastoma Formation Requires Unconventional CD4 T Cells and Arginase-1-Dependent Myeloid Cells. Cancer Res. 2021;81:5047-5059 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 2a
Nordlohne J, Hulsmann I, Schwafertz S, Zgrajek J, Grundmann M, von Vietinghoff S, et al. A flow cytometry approach reveals heterogeneity in conventional subsets of murine renal mononuclear phagocytes. Sci Rep. 2021;11:13251 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...
Amoozgar Z, Kloepper J, Ren J, Tay R, Kazer S, Kiner E, et al. Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas. Nat Commun. 2021;12:2582 pubmed publisher
  • flow cytometry; mouse; 1:50; loading ...; fig 6b
Manrique Acevedo C, Padilla J, Naz H, Woodford M, Ghiarone T, Aroor A, et al. Mineralocorticoid Receptor in Myeloid Cells Mediates Angiotensin II-Induced Vascular Dysfunction in Female Mice. Front Physiol. 2021;12:588358 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Roux C, Mucciolo G, Kopecka J, Novelli F, Riganti C, Cappello P. IL17A Depletion Affects the Metabolism of Macrophages Treated with Gemcitabine. Antioxidants (Basel). 2021;10: pubmed publisher
  • flow cytometry; mouse
Chu A, Kok S, TSUI J, Lin M, Aguirre B, Wadehra M. Epithelial membrane protein 2 (Emp2) modulates innate immune cell population recruitment at the maternal-fetal interface. J Reprod Immunol. 2021;145:103309 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5a
Xiao Y, Shu L, Wu X, Liu Y, Cheong L, Liao B, et al. Fatty acid binding protein 4 promotes autoimmune diabetes by recruitment and activation of pancreatic islet macrophages. JCI Insight. 2021;6: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s26
Santos Zas I, Lemari xe9 J, Zlatanova I, Cachanado M, Seghezzi J, Benamer H, et al. Cytotoxic CD8+ T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling. Nat Commun. 2021;12:1483 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s4f
Wolfsberger J, Sakil H, Zhou L, van Bree N, Baldisseri E, de Souza Ferreira S, et al. TAp73 represses NF-κB-mediated recruitment of tumor-associated macrophages in breast cancer. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 6d
Zhang Y, Liu J, Wang X, Zhang J, Xie C. Extracellular vesicle-encapsulated microRNA-23a from dorsal root ganglia neurons binds to A20 and promotes inflammatory macrophage polarization following peripheral nerve injury. Aging (Albany NY). 2021;13:6752-6764 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5d
Chen J, Cao X, Li B, Zhao Z, Chen S, Lai S, et al. Warburg Effect Is a Cancer Immune Evasion Mechanism Against Macrophage Immunosurveillance. Front Immunol. 2020;11:621757 pubmed publisher
  • flow cytometry; mouse; 1:50; fig 7
Mpekris F, Panagi M, Voutouri C, Martin J, Samuel R, Takahashi S, et al. Normalizing the Microenvironment Overcomes Vessel Compression and Resistance to Nano-immunotherapy in Breast Cancer Lung Metastasis. Adv Sci (Weinh). 2021;8:2001917 pubmed publisher
  • flow cytometry; mouse; 1:400; loading ...; fig e10e
Mastorakos P, Mihelson N, Luby M, Burks S, Johnson K, Hsia A, et al. Temporally distinct myeloid cell responses mediate damage and repair after cerebrovascular injury. Nat Neurosci. 2021;24:245-258 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3a
Ogura Y, Tajiri K, Murakoshi N, Xu D, Yonebayashi S, Li S, et al. Neutrophil Elastase Deficiency Ameliorates Myocardial Injury Post Myocardial Infarction in Mice. Int J Mol Sci. 2021;22: pubmed publisher
  • flow cytometry; mouse; 1:100; fig 4a
Boulet N, Luijten I, Cannon B, Nedergaard J. Thermogenic recruitment of brown and brite/beige adipose tissues is not obligatorily associated with macrophage accretion or attrition. Am J Physiol Endocrinol Metab. 2020;: pubmed publisher
  • flow cytometry; mouse; loading ...
Myers D, Abram C, Wildes D, Belwafa A, Welsh A, Schulze C, et al. Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity. Front Immunol. 2020;11:576310 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 2i
Hall B, Gleiberman A, Strom E, Krasnov P, Frescas D, Vujcic S, et al. Immune checkpoint protein VSIG4 as a biomarker of aging in murine adipose tissue. Aging Cell. 2020;19:e13219 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2d, 2e
Zheng D, Gao F, Cheng Q, Bao P, Dong X, Fan J, et al. A vaccine-based nanosystem for initiating innate immunity and improving tumor immunotherapy. Nat Commun. 2020;11:1985 pubmed publisher
  • flow cytometry; mouse; loading ...
Chao Y, Liang C, Tao H, Du Y, Wu D, Dong Z, et al. Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses. Sci Adv. 2020;6:eaaz4204 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 3s1
Helsley R, Varadharajan V, Brown A, Gromovsky A, Schugar R, Ramachandiran I, et al. Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2e
Chakarov S, Lim H, Tan L, Lim S, See P, Lum J, et al. Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches. Science. 2019;363: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4a
Kubli S, Bassi C, Roux C, Wakeham A, Göbl C, Zhou W, et al. AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer. Proc Natl Acad Sci U S A. 2019;116:3604-3613 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5b
Liu M, O Connor R, Trefely S, Graham K, Snyder N, Beatty G. Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated 'don't-eat-me' signal. Nat Immunol. 2019;20:265-275 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2
Kaplanov I, Carmi Y, Kornetsky R, Shemesh A, Shurin G, Shurin M, et al. Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation. Proc Natl Acad Sci U S A. 2019;116:1361-1369 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4
Cortés Selva D, Elvington A, Ready A, Rajwa B, Pearce E, Randolph G, et al. Schistosoma mansoni Infection-Induced Transcriptional Changes in Hepatic Macrophage Metabolism Correlate With an Athero-Protective Phenotype. Front Immunol. 2018;9:2580 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2b
Ushio A, Arakaki R, Otsuka K, Yamada A, Tsunematsu T, Kudo Y, et al. CCL22-Producing Resident Macrophages Enhance T Cell Response in Sjögren's Syndrome. Front Immunol. 2018;9:2594 pubmed publisher
  • flow cytometry; mouse; fig 2e
Cabron A, El Azzouzi K, Boss M, Arnold P, Schwarz J, Rosas M, et al. Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells. J Immunol. 2018;201:3106-3118 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Kyung D, Sung H, Kim Y, Kim K, Cho S, Choi J, et al. Global transcriptome analysis identifies weight regain-induced activation of adaptive immune responses in white adipose tissue of mice. Int J Obes (Lond). 2018;42:755-764 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3g
Xi J, Huang Q, Wang L, Ma X, Deng Q, Kumar M, et al. miR-21 depletion in macrophages promotes tumoricidal polarization and enhances PD-1 immunotherapy. Oncogene. 2018;37:3151-3165 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1b
Macdougall C, Wood E, Loschko J, Scagliotti V, Cassidy F, Robinson M, et al. Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets. Cell Metab. 2018;27:588-601.e4 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1a
Panduro M, Benoist C, Mathis D. Treg cells limit IFN-? production to control macrophage accrual and phenotype during skeletal muscle regeneration. Proc Natl Acad Sci U S A. 2018;115:E2585-E2593 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 4a
Zhu Y, Zhou J, Feng Y, Chen L, Zhang L, Yang F, et al. Control of Intestinal Inflammation, Colitis-Associated Tumorigenesis, and Macrophage Polarization by Fibrinogen-Like Protein 2. Front Immunol. 2018;9:87 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3d
Perry C, Muñoz Rojas A, Meeth K, Kellman L, Amezquita R, Thakral D, et al. Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity. J Exp Med. 2018;215:877-893 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1d
Daley D, Mani V, Mohan N, Akkad N, Pandian G, Savadkar S, et al. NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma. J Exp Med. 2017;214:1711-1724 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5c
A Gonzalez N, Quintana J, Garcia Silva S, Mazariegos M, González de la Aleja A, Nicolás Ávila J, et al. Phagocytosis imprints heterogeneity in tissue-resident macrophages. J Exp Med. 2017;214:1281-1296 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4f
Daley D, Mani V, Mohan N, Akkad N, Ochi A, Heindel D, et al. Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance. Nat Med. 2017;23:556-567 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2j
Hui X, Zhang M, Gu P, Li K, Gao Y, Wu D, et al. Adipocyte SIRT1 controls systemic insulin sensitivity by modulating macrophages in adipose tissue. EMBO Rep. 2017;18:645-657 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5d
Hammer A, Yang G, Friedrich J, Kovacs A, Lee D, Grave K, et al. Role of the receptor Mas in macrophage-mediated inflammation in vivo. Proc Natl Acad Sci U S A. 2016;113:14109-14114 pubmed
Graça F, Stephan A, Minden Birkenmaier B, Shirinifard A, Wang Y, Demontis F, et al. Platelet-derived chemokines promote skeletal muscle regeneration by guiding neutrophil recruitment to injured muscles. Nat Commun. 2023;14:2900 pubmed publisher
Vanneste D, Bai Q, Hasan S, Peng W, Pirottin D, Schyns J, et al. MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation. Nat Immunol. 2023;24:827-840 pubmed publisher
Cheong L, Wang B, Wang Q, Jin L, Kwok K, Wu X, et al. Fibroblastic reticular cells in lymph node potentiate white adipose tissue beiging through neuro-immune crosstalk in male mice. Nat Commun. 2023;14:1213 pubmed publisher
Mizutani T, Ano T, Yoshioka Y, Mizuta S, Takemoto K, Ouchi Y, et al. Neutrophil S100A9 supports M2 macrophage niche formation in granulomas. iScience. 2023;26:106081 pubmed publisher
Yang L, Guo P, Wang P, Wang W, Liu J. IL-6/ERK signaling pathway participates in type I IFN-programmed, unconventional M2-like macrophage polarization. Sci Rep. 2023;13:1827 pubmed publisher
Garc xed a Garc xed a A, Pigeot S, Martin I. Engineering of immunoinstructive extracellular matrices for enhanced osteoinductivity. Bioact Mater. 2023;24:174-184 pubmed publisher
Deville S, Garcia Romeu H, Oeyen E, Mertens I, Nelissen I, Salvati A. Macrophages Release Extracellular Vesicles of Different Properties and Composition Following Exposure to Nanoparticles. Int J Mol Sci. 2022;24: pubmed publisher
Draijer C, Florez Sampedro L, Reker Smit C, Post E, van Dijk F, Melgert B. Explaining the polarized macrophage pool during murine allergic lung inflammation. Front Immunol. 2022;13:1056477 pubmed publisher
Li H, Xie J, Guo X, Yang G, Cai B, Liu J, et al. Bifidobacterium spp. and their metabolite lactate protect against acute pancreatitis via inhibition of pancreatic and systemic inflammatory responses. Gut Microbes. 2022;14:2127456 pubmed publisher
Chryplewicz A, Scotton J, Tichet M, Zomer A, Shchors K, Joyce J, et al. Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity. Cancer Cell. 2022;40:1111-1127.e9 pubmed publisher
Zhu Q, Xiao Y, Jiang M, Liu X, Cui Y, Hao H, et al. N-acetylcysteine attenuates atherosclerosis progression in aging LDL receptor deficient mice with preserved M2 macrophages and increased CD146. Atherosclerosis. 2022;357:41-50 pubmed publisher
Scheyltjens I, Van Hove H, De Vlaminck K, Kancheva D, Bastos J, Vara P xe9 rez M, et al. Single-cell RNA and protein profiling of immune cells from the mouse brain and its border tissues. Nat Protoc. 2022;17:2354-2388 pubmed publisher
Zhang C, Huang J, Zeng Z, He S, Cheng P, Li J, et al. Catalytical nano-immunocomplexes for remote-controlled sono-metabolic checkpoint trimodal cancer therapy. Nat Commun. 2022;13:3468 pubmed publisher
Herrada A, Olate Briones A, Lazo Amador R, Liu C, Hern xe1 ndez Rojas B, Riadi G, et al. Lymph Leakage Promotes Immunosuppression by Enhancing Anti-Inflammatory Macrophage Polarization. Front Immunol. 2022;13:841641 pubmed publisher
Chen Y, Bai L, Dilimulati D, Shao S, Qiu C, Liu T, et al. Periodontitis Salivary Microbiota Aggravates Ischemic Stroke Through IL-17A. Front Neurosci. 2022;16:876582 pubmed publisher
Hailemichael Y, Johnson D, Abdel Wahab N, Foo W, Bentebibel S, Daher M, et al. Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity. Cancer Cell. 2022;40:509-523.e6 pubmed publisher
Xu Z, Lin L, Fan Y, Huselstein C, De Isla N, He X, et al. Secretome of Mesenchymal Stem Cells from Consecutive Hypoxic Cultures Promotes Resolution of Lung Inflammation by Reprogramming Anti-Inflammatory Macrophages. Int J Mol Sci. 2022;23: pubmed publisher
Yu H, Bai Y, Qiu J, He X, Xiong J, Dai Q, et al. Pseudomonas aeruginosa PcrV Enhances the Nitric Oxide-Mediated Tumoricidal Activity of Tumor-Associated Macrophages via a TLR4/PI3K/AKT/mTOR-Glycolysis-Nitric Oxide Circuit. Front Oncol. 2021;11:736882 pubmed publisher
Gao L, Jiang W, Liu H, Chen Z, Lin Y. Receptor-selective interleukin-4 mutein attenuates laser-induced choroidal neovascularization through the regulation of macrophage polarization in mice. Exp Ther Med. 2021;22:1367 pubmed publisher
He S, Wang S, Liu S, Li Z, Liu X, Wu J. Baicalein Potentiated M1 Macrophage Polarization in Cancer Through Targeting PI3Kγ/ NF-κB Signaling. Front Pharmacol. 2021;12:743837 pubmed publisher
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De Simone G, Andreata F, Blériot C, Fumagalli V, Laura C, Garcia Manteiga J, et al. Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming. Immunity. 2021;54:2089-2100.e8 pubmed publisher
Guo P, Yang L, Zhang M, Zhang Y, Tong Y, Cao Y, et al. A Monocyte-Orchestrated IFN-I-to-IL-4 Cytokine Axis Instigates Protumoral Macrophages and Thwarts Poly(I:C) Therapy. J Immunol. 2021;207:408-420 pubmed publisher
Mohammadi M, Rodriguez S, Luong J, Li S, Cao R, Alshetaiwi H, et al. Exosome loaded immunomodulatory biomaterials alleviate local immune response in immunocompetent diabetic mice post islet xenotransplantation. Commun Biol. 2021;4:685 pubmed publisher
Barkaway A, Rolas L, Joulia R, Bodkin J, Lenn T, Owen Woods C, et al. Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage. Immunity. 2021;54:1494-1510.e7 pubmed publisher
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Chakraborty A, Pinar A, Lam M, Bourke J, Royce S, Selomulya C, et al. Pulmonary myeloid cell uptake of biodegradable nanoparticles conjugated with an anti-fibrotic agent provides a novel strategy for treating chronic allergic airways disease. Biomaterials. 2021;273:120796 pubmed publisher
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Budhu S, Giese R, Gupta A, Fitzgerald K, Zappasodi R, Schad S, et al. Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma. Cell Rep. 2021;34:108620 pubmed publisher
Hu H, Liang X, Li H, Du C, Hao J, Wang H, et al. The armed oncolytic adenovirus ZD55-IL-24 eradicates melanoma by turning the tumor cells from the self-state into the nonself-state besides direct killing. Cell Death Dis. 2020;11:1022 pubmed publisher
Ren Y, Chen Y, Zheng X, Wang H, Kang X, Tang J, et al. Human amniotic epithelial cells ameliorate kidney damage in ischemia-reperfusion mouse model of acute kidney injury. Stem Cell Res Ther. 2020;11:410 pubmed publisher
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Eixarch H, Calvo Barreiro L, Costa C, Reverter Vives G, Castillo M, Gil V, et al. Inhibition of the BMP Signaling Pathway Ameliorated Established Clinical Symptoms of Experimental Autoimmune Encephalomyelitis. Neurotherapeutics. 2020;17:1988-2003 pubmed publisher
Enam S, Kader S, Bodkin N, Lyon J, Calhoun M, Azrak C, et al. Evaluation of M2-like macrophage enrichment after diffuse traumatic brain injury through transient interleukin-4 expression from engineered mesenchymal stromal cells. J Neuroinflammation. 2020;17:197 pubmed publisher
Chandran S, Schilke R, Blackburn C, Yurochko A, Mirza R, Scott R, et al. Lipin-1 Contributes to IL-4 Mediated Macrophage Polarization. Front Immunol. 2020;11:787 pubmed publisher
Sato H, Taketomi Y, Miki Y, Murase R, Yamamoto K, Murakami M. Secreted Phospholipase PLA2G2D Contributes to Metabolic Health by Mobilizing ω3 Polyunsaturated Fatty Acids in WAT. Cell Rep. 2020;31:107579 pubmed publisher
Garre J, Silva H, Lafaille J, Yang G. P2X7 receptor inhibition ameliorates dendritic spine pathology and social behavioral deficits in Rett syndrome mice. Nat Commun. 2020;11:1784 pubmed publisher
Wang L, Zhang H, Sun L, Gao W, Xiong Y, Ma A, et al. Manipulation of macrophage polarization by peptide-coated gold nanoparticles and its protective effects on acute lung injury. J Nanobiotechnology. 2020;18:38 pubmed publisher
Brykczynska U, Geigges M, Wiedemann S, Dror E, Böni Schnetzler M, Hess C, et al. Distinct Transcriptional Responses across Tissue-Resident Macrophages to Short-Term and Long-Term Metabolic Challenge. Cell Rep. 2020;30:1627-1643.e7 pubmed publisher
Lee D, Lim J, Cho K. Differential Activation of Macrophages Based on Their Environment in Advanced Age. Chonnam Med J. 2020;56:12-19 pubmed publisher
Chen L, Christian D, Kochanowsky J, Phan A, Clark J, Wang S, et al. The Toxoplasma gondii virulence factor ROP16 acts in cis and trans, and suppresses T cell responses. J Exp Med. 2020;217: pubmed publisher
Hightower R, Reid A, Gibbs D, Wang Y, Widrick J, Kunkel L, et al. The SINE Compound KPT-350 Blocks Dystrophic Pathologies in DMD Zebrafish and Mice. Mol Ther. 2020;28:189-201 pubmed publisher
Kumaran Satyanarayanan S, El Kebir D, Soboh S, Butenko S, Sekheri M, Saadi J, et al. IFN-β is a macrophage-derived effector cytokine facilitating the resolution of bacterial inflammation. Nat Commun. 2019;10:3471 pubmed publisher
Carestia A, Mena H, Olexen C, Ortiz Wilczyñski J, Negrotto S, Errasti A, et al. Platelets Promote Macrophage Polarization toward Pro-inflammatory Phenotype and Increase Survival of Septic Mice. Cell Rep. 2019;28:896-908.e5 pubmed publisher
Cianciaruso C, Beltraminelli T, Duval F, Nassiri S, Hamelin R, Mozes A, et al. Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles. Cell Rep. 2019;27:3062-3080.e11 pubmed publisher
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Schmidleithner L, Thabet Y, Schönfeld E, Köhne M, Sommer D, Abdullah Z, et al. Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction. Immunity. 2019;50:1232-1248.e14 pubmed publisher
Silva H, Bafica A, Rodrigues Luiz G, Chi J, Santos P, Reis B, et al. Vasculature-associated fat macrophages readily adapt to inflammatory and metabolic challenges. J Exp Med. 2019;216:786-806 pubmed publisher
Vega Angeles V, Terrazas L, Ledesma Soto Y, Jimenez L, Landa A. Taenia solium glutathione transferase fraction activates macrophages and favors the development of Th1-type response. Biosci Rep. 2019;39: pubmed publisher
Kiyohara H, Sujino T, Teratani T, Miyamoto K, Arai M, Nomura E, et al. Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells. Cell Mol Gastroenterol Hepatol. 2019;7:135-156 pubmed publisher
Liu N, Luo J, Kuang D, Xu S, Duan Y, Xia Y, et al. Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression. J Clin Invest. 2019;129:631-646 pubmed publisher
Miyachi Y, Tsuchiya K, Shiba K, Mori K, Komiya C, Ogasawara N, et al. A reduced M1-like/M2-like ratio of macrophages in healthy adipose tissue expansion during SGLT2 inhibition. Sci Rep. 2018;8:16113 pubmed publisher
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product information
Antigen :
CD206
Apps. Abbrev. :
ICFC, FC, IHC-F
Cat # :
141712
Clone :
C068C2
Item :
Alexa Fluor® 647 anti-mouse CD206 (MMR)
Isotype :
Rat IgG2a, κ
Other Names :
MMR (macrophage mannose receptor), MR (mannose receptor), MRC1
Size :
100 μg
Price (USD) :
293 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
A647
Immunogen :
Recombinant mouse CD206 (MMR)
Application Notes :
Clone C068C2 recognizes a region similar to clone MR5D3, based on the ability of the clones to block each other. Additional reported applications (for the relevant formats) include: spatial biology (IBEX)^4,5.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA