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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-mouse CD206 (MMR)
catalog :
141708
quantity :
100 μg
price :
250 USD
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
C068C2
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 49
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:200; loading ...
Farbehi N, Patrick R, Dorison A, Xaymardan M, Janbandhu V, Wystub Lis K, et al. Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4a
Kubli S, Bassi C, Roux C, Wakeham A, Göbl C, Zhou W, et al. AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer. Proc Natl Acad Sci U S A. 2019;116:3604-3613 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2d
Xue N, Zhou Q, Ji M, Jin J, Lai F, Chen J, et al. Chlorogenic acid inhibits glioblastoma growth through repolarizating macrophage from M2 to M1 phenotype. Sci Rep. 2017;7:39011 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2c
Hellström Erkenstam N, Smith P, Fleiss B, Nair S, Svedin P, Wang W, et al. Temporal Characterization of Microglia/Macrophage Phenotypes in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury. Front Cell Neurosci. 2016;10:286 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2b
Tahiri H, Omri S, Yang C, Duhamel F, Samarani S, Ahmad A, et al. Lymphocytic Microparticles Modulate Angiogenic Properties of Macrophages in Laser-induced Choroidal Neovascularization. Sci Rep. 2016;6:37391 pubmed publisher
Yoon J, Um H, Jang J, Bae Y, Park W, Kim H, et al. Eosinophil Activation by Toll-Like Receptor 4 Ligands Regulates Macrophage Polarization. Front Cell Dev Biol. 2019;7:329 pubmed publisher
Shang W, Chen G, Li Y, Zhuo Y, Wang Y, Fang Z, et al. Static Magnetic Field Accelerates Diabetic Wound Healing by Facilitating Resolution of Inflammation. J Diabetes Res. 2019;2019:5641271 pubmed publisher
Kurelac I, Abarrategi A, Ragazzi M, Iommarini L, Umesh Ganesh N, Snoeks T, et al. A Humanized Bone Niche Model Reveals Bone Tissue Preservation Upon Targeting Mitochondrial Complex I in Pseudo-Orthotopic Osteosarcoma. J Clin Med. 2019;8: pubmed publisher
Liu C, Li P, Li H, Wang S, Ding L, Wang H, et al. TREM2 regulates obesity-induced insulin resistance via adipose tissue remodeling in mice of high-fat feeding. J Transl Med. 2019;17:300 pubmed publisher
Di Mitri D, Mirenda M, Vasilevska J, Calcinotto A, Delaleu N, Revandkar A, et al. Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer. Cell Rep. 2019;28:2156-2168.e5 pubmed publisher
Mariani S, Li Z, Rice S, Krieg C, Fragkogianni S, Robinson M, et al. Pro-inflammatory Aorta-Associated Macrophages Are Involved in Embryonic Development of Hematopoietic Stem Cells. Immunity. 2019;: pubmed publisher
Kurelac I, Iommarini L, Vatrinet R, Amato L, De Luise M, Leone G, et al. Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses. Nat Commun. 2019;10:903 pubmed publisher
Kiyohara H, Sujino T, Teratani T, Miyamoto K, Arai M, Nomura E, et al. Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells. Cell Mol Gastroenterol Hepatol. 2019;7:135-156 pubmed publisher
Subramanian K, Neill D, Malak H, Spelmink L, Khandaker S, Dalla Libera Marchiori G, et al. Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival. Nat Microbiol. 2019;4:62-70 pubmed publisher
Baardman J, Verberk S, Prange K, van Weeghel M, van der Velden S, Ryan D, et al. A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia. Cell Rep. 2018;25:2044-2052.e5 pubmed publisher
Kumar M, Du J, Lagoudas G, Jiao Y, Sawyer A, Drummond D, et al. Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics. Cell Rep. 2018;25:1458-1468.e4 pubmed publisher
Gubin M, Esaulova E, Ward J, Malkova O, Runci D, Wong P, et al. High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy. Cell. 2018;175:1014-1030.e19 pubmed publisher
Pilch Z, Tonecka K, Braniewska A, Sas Z, Skorzynski M, Boon L, et al. Antitumor Activity of TLR7 Is Potentiated by CD200R Antibody Leading to Changes in the Tumor Microenvironment. Cancer Immunol Res. 2018;6:930-940 pubmed publisher
Luo J, Qian A, Oetjen L, Yu W, Yang P, Feng J, et al. TRPV4 Channel Signaling in Macrophages Promotes Gastrointestinal Motility via Direct Effects on Smooth Muscle Cells. Immunity. 2018;49:107-119.e4 pubmed publisher
Rhys H, Dell accio F, Pitzalis C, Moore A, Norling L, Perretti M. Neutrophil Microvesicles from Healthy Control and Rheumatoid Arthritis Patients Prevent the Inflammatory Activation of Macrophages. EBioMedicine. 2018;29:60-69 pubmed publisher
Wang C, Li Y, Chen H, Huang K, Liu X, Qiu M, et al. CYP4X1 Inhibition by Flavonoid CH625 Normalizes Glioma Vasculature through Reprogramming TAMs via CB2 and EGFR-STAT3 Axis. J Pharmacol Exp Ther. 2018;365:72-83 pubmed publisher
Wang Q, He Z, Huang M, Liu T, Wang Y, Xu H, et al. Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2α. Nat Commun. 2018;9:559 pubmed publisher
Syed I, Lee J, Moraes Vieira P, Donaldson C, Sontheimer A, Aryal P, et al. Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis. Cell Metab. 2018;27:419-427.e4 pubmed publisher
Yan J, Tie G, Wang S, Tutto A, DeMarco N, Khair L, et al. Diabetes impairs wound healing by Dnmt1-dependent dysregulation of hematopoietic stem cells differentiation towards macrophages. Nat Commun. 2018;9:33 pubmed publisher
Linde N, Casanova Acebes M, Sosa M, Mortha A, Rahman A, Farias E, et al. Macrophages orchestrate breast cancer early dissemination and metastasis. Nat Commun. 2018;9:21 pubmed publisher
Lee S, Charmoy M, Romano A, Paun A, Chaves M, Cope F, et al. Mannose receptor high, M2 dermal macrophages mediate nonhealing Leishmania major infection in a Th1 immune environment. J Exp Med. 2018;215:357-375 pubmed publisher
Zhang X, Liu M, Qiao L, Zhang X, Liu X, Dong M, et al. Ginsenoside Rb1 enhances atherosclerotic plaque stability by skewing macrophages to the M2 phenotype. J Cell Mol Med. 2018;22:409-416 pubmed publisher
Durga Devi T, Babu M, Mäkinen P, Kaikkonen M, Heinaniemi M, Laakso H, et al. Aggravated Postinfarct Heart Failure in Type 2 Diabetes Is Associated with Impaired Mitophagy and Exaggerated Inflammasome Activation. Am J Pathol. 2017;187:2659-2673 pubmed publisher
Nasti A, Sakai Y, Seki A, Buffa G, Komura T, Mochida H, et al. The CD45+ fraction in murine adipose tissue derived stromal cells harbors immune-inhibitory inflammatory cells. Eur J Immunol. 2017;47:2163-2174 pubmed publisher
Gundra U, Girgis N, Gonzalez M, San Tang M, Van Der Zande H, Lin J, et al. Vitamin A mediates conversion of monocyte-derived macrophages into tissue-resident macrophages during alternative activation. Nat Immunol. 2017;18:642-653 pubmed publisher
Poh A, Love C, Masson F, Preaudet A, Tsui C, Whitehead L, et al. Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression. Cancer Cell. 2017;31:563-575.e5 pubmed publisher
Chang C, Wan J, Li Q, Renfroe S, Heller N, Wang J. Alternative activation-skewed microglia/macrophages promote hematoma resolution in experimental intracerebral hemorrhage. Neurobiol Dis. 2017;103:54-69 pubmed publisher
Liu J, Xue Y, Dong D, Xiao C, Lin C, Wang H, et al. CCR2- and CCR2+ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion. Mucosal Immunol. 2017;10:1145-1159 pubmed publisher
Jeong J, Kim K, Lim D, Kim K, Kim H, Lee S, et al. Microvasculature remodeling in the mouse lower gut during inflammaging. Sci Rep. 2017;7:39848 pubmed publisher
Huo M, Huang Y, Qu D, Zhang H, Wong W, Chawla A, et al. Myeloid Bmal1 deletion increases monocyte recruitment and worsens atherosclerosis. FASEB J. 2017;31:1097-1106 pubmed publisher
Sadtler K, Allen B, Estrellas K, Housseau F, Pardoll D, Elisseeff J. The Scaffold Immune Microenvironment: Biomaterial-Mediated Immune Polarization in Traumatic and Nontraumatic Applications<sup/>. Tissue Eng Part A. 2017;23:1044-1053 pubmed publisher
Qiu J, Wang L, Zhang R, Ge K, Guo H, Liu X, et al. Identification of a TNF-α inducer MIC3 originating from the microneme of non-cystogenic, virulent Toxoplasma gondii. Sci Rep. 2016;6:39407 pubmed publisher
Cardona S, Mendiola A, Yang Y, Adkins S, Torres V, Cardona A. Disruption of Fractalkine Signaling Leads to Microglial Activation and Neuronal Damage in the Diabetic Retina. ASN Neuro. 2015;7: pubmed publisher
Dai K, Huang L, Sun X, Yang L, Gong Z. Hepatic CD206-positive macrophages express amphiregulin to promote the immunosuppressive activity of regulatory T cells in HBV infection. J Leukoc Biol. 2015;98:1071-80 pubmed publisher
Taguchi K, Okada A, Hamamoto S, Iwatsuki S, Naiki T, Ando R, et al. Proinflammatory and Metabolic Changes Facilitate Renal Crystal Deposition in an Obese Mouse Model of Metabolic Syndrome. J Urol. 2015;194:1787-96 pubmed publisher
Moya Pérez A, Neef A, Sanz Y. Bifidobacterium pseudocatenulatum CECT 7765 Reduces Obesity-Associated Inflammation by Restoring the Lymphocyte-Macrophage Balance and Gut Microbiota Structure in High-Fat Diet-Fed Mice. PLoS ONE. 2015;10:e0126976 pubmed publisher
Lasky C, Olson R, Brown C. Macrophage Polarization during Murine Lyme Borreliosis. Infect Immun. 2015;83:2627-35 pubmed publisher
Mylonas K, Jenkins S, Castellan R, Rückerl D, McGregor K, Phythian Adams A, et al. The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an 'M2' phenotype in response to Th2 immunologic challenge. Immunobiology. 2015;220:924-33 pubmed publisher
Giordano C, Mojumdar K, Liang F, Lemaire C, Li T, Richardson J, et al. Toll-like receptor 4 ablation in mdx mice reveals innate immunity as a therapeutic target in Duchenne muscular dystrophy. Hum Mol Genet. 2015;24:2147-62 pubmed publisher
Canan C, Gokhale N, Carruthers B, Lafuse W, Schlesinger L, Torrelles J, et al. Characterization of lung inflammation and its impact on macrophage function in aging. J Leukoc Biol. 2014;96:473-80 pubmed publisher
Taguchi K, Okada A, Kitamura H, Yasui T, Naiki T, Hamamoto S, et al. Colony-stimulating factor-1 signaling suppresses renal crystal formation. J Am Soc Nephrol. 2014;25:1680-97 pubmed publisher
Ito H, Yan X, Nagata N, Aritake K, Katsumata Y, Matsuhashi T, et al. PGD2-CRTH2 pathway promotes tubulointerstitial fibrosis. J Am Soc Nephrol. 2012;23:1797-809 pubmed publisher
He H, Xu J, Warren C, Duan D, Li X, Wu L, et al. Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages. Blood. 2012;120:3152-62 pubmed publisher
Keller J, Catala Lehnen P, Wintges K, Schulze J, Bickert T, Ito W, et al. Transgenic over-expression of interleukin-33 in osteoblasts results in decreased osteoclastogenesis. Biochem Biophys Res Commun. 2012;417:217-22 pubmed publisher
product information
Antigen :
CD206
Apps. Abbrev. :
Intracellular Staining for Flow Cytometry, Flow Cytometry
Cat # :
141708
Clone :
C068C2
Item :
APC anti-mouse CD206 (MMR)
Isotype :
Rat IgG2a, κ
Other Names :
MMR (macrophage mannose receptor), MR (mannose receptor), MRC1
Size :
100 μg
Price (USD) :
250 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
APC
Immunogen :
Recombinant mouse CD206 (MMR)
Application Notes :
Clone C068C2 recognizes a region similar to clone MR5D3, based on the ability of the clones to block each other.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA