product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-mouse H-2Kb bound to SIINFEKL
catalog :
141605
quantity :
25 μg
price :
113 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
25-D1.16
reactivity :
mouse
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
citations: 24
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:200; loading ...; fig 1c
Gejman R, Chang A, Jones H, DiKun K, Hakimi A, Schietinger A, et al. Rejection of immunogenic tumor clones is limited by clonal fraction. elife. 2018;7: pubmed publisher
  • western blot; mouse
Pérez Girón J, Gómez Medina S, Lüdtke A, Munoz Fontela C. Intranasal Administration of Recombinant Influenza Vaccines in Chimeric Mouse Models to Study Mucosal Immunity. J Vis Exp. 2015;:e52803 pubmed publisher
Hao H, Wu S, Lin J, Zheng Z, Zhou Y, Zhang Y, et al. Immunization against Zika by entrapping live virus in a subcutaneous self-adjuvanting hydrogel. Nat Biomed Eng. 2023;7:928-942 pubmed publisher
Li Y, Zhang H, Wang R, Wang Y, Li R, Zhu M, et al. Tumor Cell Nanovaccines Based on Genetically Engineered Antibody-Anchored Membrane. Adv Mater. 2023;35:e2208923 pubmed publisher
Ou W, Stewart S, White A, Kwizera E, Xu J, Fang Y, et al. In-situ cryo-immune engineering of tumor microenvironment with cold-responsive nanotechnology for cancer immunotherapy. Nat Commun. 2023;14:392 pubmed publisher
Li J, Huang D, Lei B, Huang J, Yang L, Nie M, et al. VLA-4 suppression by senescence signals regulates meningeal immunity and leptomeningeal metastasis. elife. 2022;11: pubmed publisher
Malka Y, Alkan F, Ju S, K xf6 rner P, Pataskar A, Shulman E, et al. Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential. Mol Cell. 2022;82:3840-3855.e8 pubmed publisher
Zhang Y, Sriramaneni R, Clark P, Jagodinsky J, Ye M, Jin W, et al. Multifunctional nanoparticle potentiates the in situ vaccination effect of radiation therapy and enhances response to immune checkpoint blockade. Nat Commun. 2022;13:4948 pubmed publisher
Yan J, Chen Y, Patel A, Warda S, Lee C, Nixon B, et al. Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert microenvironment and is sensitized by immunogenic viruses. J Clin Invest. 2022;132: pubmed publisher
Fusciello M, Yl xf6 sm xe4 ki E, Feola S, Uoti A, Martins B, Aalto K, et al. A novel cancer vaccine for melanoma based on an approved vaccine against measles, mumps, and rubella. Mol Ther Oncolytics. 2022;25:137-145 pubmed publisher
Leary N, Walser S, He Y, Cousin N, Pereira P, Gallo A, et al. Melanoma-derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes. J Extracell Vesicles. 2022;11:e12197 pubmed publisher
Shen M, Smith H, Wei Y, Jiang Y, Zhao S, Wang N, et al. Pharmacological disruption of the MTDH-SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer. Nat Cancer. 2022;3:60-74 pubmed publisher
Song T, Long M, Zhao H, Zou M, Fan H, Liu Y, et al. Tumor evolution selectively inactivates the core microRNA machinery for immune evasion. Nat Commun. 2021;12:7003 pubmed publisher
Champagne J, Pataskar A, Blommaert N, Nagel R, Wernaart D, Ramalho S, et al. Oncogene-dependent sloppiness in mRNA translation. Mol Cell. 2021;81:4709-4721.e9 pubmed publisher
Sun L, Kees T, Almeida A, Liu B, He X, Ng D, et al. Activating a collaborative innate-adaptive immune response to control metastasis. Cancer Cell. 2021;39:1361-1374.e9 pubmed publisher
Zhang L, Huang J, Chen X, Pan C, He Y, Su R, et al. Self-assembly nanovaccine containing TLR7/8 agonist and STAT3 inhibitor enhances tumor immunotherapy by augmenting tumor-specific immune response. J Immunother Cancer. 2021;9: pubmed publisher
Yl xf6 sm xe4 ki E, Fusciello M, Martins B, Feola S, Hamdan F, Chiaro J, et al. Novel personalized cancer vaccine platform based on Bacillus Calmette-Guèrin. J Immunother Cancer. 2021;9: pubmed publisher
Pitsch J, Van Loo K, Gallus M, Dik A, Kamalizade D, Baumgart A, et al. CD8+ T-Lymphocyte-Driven Limbic Encephalitis Results in Temporal Lobe Epilepsy. Ann Neurol. 2021;89:666-685 pubmed publisher
Bartok O, Pataskar A, Nagel R, Laos M, Goldfarb E, Hayoun D, et al. Anti-tumour immunity induces aberrant peptide presentation in melanoma. Nature. 2021;590:332-337 pubmed publisher
Drijvers J, Gillis J, Muijlwijk T, Nguyen T, Gaudiano E, Harris I, et al. Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells. Cancer Immunol Res. 2021;9:184-199 pubmed publisher
Reguzova A, Ghosh M, M xfc ller M, Rziha H, Amann R. Orf Virus-Based Vaccine Vector D1701-V Induces Strong CD8+ T Cell Response against the Transgene but Not against ORFV-Derived Epitopes. Vaccines (Basel). 2020;8: pubmed publisher
Cordeiro B, Jeon P, Boukhaled G, Corrado M, Lapohos O, Roy D, et al. MicroRNA-9 Fine-Tunes Dendritic Cell Function by Suppressing Negative Regulators in a Cell-Type-Specific Manner. Cell Rep. 2020;31:107585 pubmed publisher
Tsuchiya N, Zhang R, Iwama T, Ueda N, Liu T, Tatsumi M, et al. Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells. Cell Rep. 2019;29:162-175.e9 pubmed publisher
Ahn J, Xia T, Rabasa Capote A, Betancourt D, Barber G. Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells. Cancer Cell. 2018;33:862-873.e5 pubmed publisher
product information
Antigen :
H-2Kb bound to SIINFEKL
Apps. Abbrev. :
FC, ICC
Cat # :
141605
Clone :
25-D1.16
Item :
APC anti-mouse H-2Kb bound to SIINFEKL
Isotype :
Mouse IgG1, κ
Other Names :
MHC class I molecule Kb bound to the peptide SIINFEKL (Kb-SIINFEKL) H-2Kb, OVA agonist peptide (OVAp), OVA-Kb, OVA257-264 (SIINFEKL)-H-2kb, OVA257-264-H-2kb
Size :
25 μg
Price (USD) :
113 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Immunogen :
SIINFEKL pulsed RMA-S cells
Application Notes :
The 25-D1.16 monoclonal antibody specifically reacts with ovalbumin-derived peptide SIINFEKL bound to H-2Kb of MHC class I, but not with unbound H-2Kb or H-2Kb bound with an irrelevant peptide. Additional reported applications (for relevant formats) include: immunofluorescence microscopy^2,3, immunohistochemical staining of frozen tissue sections^3 , and inhibition of T cell response to H-2K^b-SIINFEKL in vitro.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA