product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-mouse LAP (TGF-β1)
catalog :
141408
quantity :
50 μg
price :
242 USD
clonality :
monoclonal
host :
mouse
conjugate :
BV421
clone name :
TW7-16B4
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s5a
Prado C, Gaiazzi M, Gonzalez H, Ugalde V, Figueroa A, Osorio Barrios F, et al. Dopaminergic Stimulation of Myeloid Antigen-Presenting Cells Attenuates Signal Transducer and Activator of Transcription 3-Activation Favouring the Development of Experimental Autoimmune Encephalomyelitis. Front Immunol. 2018;9:571 pubmed publisher
Chryplewicz A, Scotton J, Tichet M, Zomer A, Shchors K, Joyce J, et al. Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity. Cancer Cell. 2022;40:1111-1127.e9 pubmed publisher
Liang X, Luo M, Shao B, Yang J, Tong A, Wang R, et al. Phosphatidylserine released from apoptotic cells in tumor induces M2-like macrophage polarization through the PSR-STAT3-JMJD3 axis. Cancer Commun (Lond). 2022;42:205-222 pubmed publisher
Bachy S, Wu Z, Gamradt P, Thierry K, Milani P, Chlasta J, et al. βig-h3-structured collagen alters macrophage phenotype and function in pancreatic cancer. iScience. 2022;25:103758 pubmed publisher
De Ponte Conti B, Miluzio A, Grassi F, Abrignani S, Biffo S, Ricciardi S. mTOR-dependent translation drives tumor infiltrating CD8+ effector and CD4+ Treg cells expansion. elife. 2021;10: pubmed publisher
Marques R, Gonzalez Nuñez M, Walker M, Gómez E, Colas R, Montero Melendez T, et al. Loss of 15-lipoxygenase disrupts Treg differentiation altering their pro-resolving functions. Cell Death Differ. 2021;28:3140-3160 pubmed publisher
Mansouri S, Katikaneni D, Gogoi H, Jin L. Monocyte-Derived Dendritic Cells (moDCs) Differentiate into Bcl6+ Mature moDCs to Promote Cyclic di-GMP Vaccine Adjuvant-Induced Memory TH Cells in the Lung. J Immunol. 2021;206:2233-2245 pubmed publisher
Dikiy S, Li J, Bai L, Jiang M, Janke L, Zong X, et al. A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance. Immunity. 2021;54:931-946.e11 pubmed publisher
Prakash M, Stojanovska L, Feehan J, Nurgali K, Donald E, Plebanski M, et al. Anti-cancer effects of polyphenol-rich sugarcane extract. PLoS ONE. 2021;16:e0247492 pubmed publisher
Russler Germain E, Yi J, Young S, Nutsch K, Wong H, Ai T, et al. Gut Helicobacter presentation by multiple dendritic cell subsets enables context-specific regulatory T cell generation. elife. 2021;10: pubmed publisher
Pasciuto E, Burton O, Roca C, Lagou V, Rajan W, Theys T, et al. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. Cell. 2020;182:625-640.e24 pubmed publisher
Mansouri S, Katikaneni D, Gogoi H, Pipkin M, Machuca T, Emtiazjoo A, et al. Lung IFNAR1hi TNFR2+ cDC2 promotes lung regulatory T cells induction and maintains lung mucosal tolerance at steady state. Mucosal Immunol. 2020;13:595-608 pubmed publisher
Zheng G, Qiu G, Ge M, He J, Huang L, Chen P, et al. Human adipose-derived mesenchymal stem cells alleviate obliterative bronchiolitis in a murine model via IDO. Respir Res. 2017;18:119 pubmed publisher
Mayo L, Cunha A, Madi A, Beynon V, Yang Z, Alvarez J, et al. IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation. Brain. 2016;139:1939-57 pubmed publisher
Culina S, Gupta N, Boisgard R, Afonso G, Gagnerault M, Dimitrov J, et al. Materno-Fetal Transfer of Preproinsulin Through the Neonatal Fc Receptor Prevents Autoimmune Diabetes. Diabetes. 2015;64:3532-42 pubmed publisher
product information
Antigen :
LAP
Apps. Abbrev. :
FC
Cat # :
141408
Clone :
TW7-16B4
Item :
Brilliant Violet 421™ anti-mouse LAP (TGF-β1)
Isotype :
Mouse IgG1, κ
Other Names :
Latency Associated Peptide (LAP), Transforming growth factor-beta 1 (TGF-b1), TGFB1, DPD1, TGF-beta1
Size :
50 μg
Price (USD) :
242 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BV421
Immunogen :
Mouse Tgfb1 -transduced P3U1 cells
Application Notes :
Clone TW7-16B4 has been reported to not cross-react with bovine LAP.^2 Several anti-LAP antibody clones have been compared and characterized for their LAP reactivity.^2 TW7-16B4 recognizes recombinant LAP, latent TGF-β, and pro-TGF-β.Additional reported applications (for relevant formats) include: Western blotting^1 and immunoprecipitation^1.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA