product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-mouse LAP (TGF-β1)
catalog :
141405
quantity :
25 μg
price :
137 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
TW7-16B4
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 22
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 3:100; loading ...; fig 3d
Alonso Herranz L, Sahún Español Á, Paredes A, Gonzalo P, Gkontra P, Núñez V, et al. Macrophages promote endothelial-to-mesenchymal transition via MT1-MMP/TGFβ1 after myocardial infarction. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3
Loh J, Xu S, Huo J, Kim S, Wang Y, Lam K. Dok3-protein phosphatase 1 interaction attenuates Card9 signaling and neutrophil-dependent antifungal immunity. J Clin Invest. 2019;129:2717-2729 pubmed publisher
  • flow cytometry; mouse; fig 3a
Wei R, Hu Y, Dong F, Xu X, Hu A, Gao G. Hepatoma cell-derived leptin downregulates the immunosuppressive function of regulatory T-cells to enhance the anti-tumor activity of CD8+ T-cells. Immunol Cell Biol. 2016;94:388-99 pubmed publisher
Yao G, Mo X, Liu S, Wang Q, Xie M, Lou W, et al. Snowflake-inspired and blink-driven flexible piezoelectric contact lenses for effective corneal injury repair. Nat Commun. 2023;14:3604 pubmed publisher
Suresh V, Dash P, Suklabaidya S, Murmu K, Sasmal P, Jogdand G, et al. MIF confers survival advantage to pancreatic CAFs by suppressing interferon pathway-induced p53-dependent apoptosis. FASEB J. 2022;36:e22449 pubmed publisher
Li Y, Ritzel R, Lei Z, Cao T, He J, Faden A, et al. Sexual dimorphism in neurological function after SCI is associated with disrupted neuroinflammation in both injured spinal cord and brain. Brain Behav Immun. 2022;101:1-22 pubmed publisher
Gerlach B, Ampomah P, Yurdagul A, Liu C, Lauring M, Wang X, et al. Efferocytosis induces macrophage proliferation to help resolve tissue injury. Cell Metab. 2021;33:2445-2463.e8 pubmed publisher
Tan X, Yi C, Zhang Y, Tang N, Xu Y, Liu Z. Ultrasound-Targeted Microbubble Destruction Alleviates Immunosuppression Induced by CD71+ Erythroid Progenitor Cells and Promotes PDL-1 Blockade Immunotherapy in the Lewis Lung Cancer Model. Front Oncol. 2021;11:768222 pubmed publisher
Zhang C, Lei L, Yang X, Ma K, Zheng H, Su Y, et al. Single-cell sequencing reveals antitumor characteristics of intratumoral immune cells in old mice. J Immunother Cancer. 2021;9: pubmed publisher
Vick S, Kolupaev O, Perou C, Serody J. Anti-PD-1 Checkpoint Therapy Can Promote the Function and Survival of Regulatory T Cells. J Immunol. 2021;207:2598-2607 pubmed publisher
Lehmkuhl P, Gentz M, Garcia de Otezya A, Grimbacher B, Schulze Koops H, Skapenko A. Dysregulated immunity in PID patients with low GARP expression on Tregs due to mutations in LRRC32. Cell Mol Immunol. 2021;18:1677-1691 pubmed publisher
Umeshappa C, Solé P, Surewaard B, Yamanouchi J, Mohapatra S, Uddin M, et al. Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP. Cell Rep. 2021;34:108919 pubmed publisher
Turner J, Stephen Victor E, Wang S, Rivas M, Abdel Gadir A, Harb H, et al. Regulatory T Cell-Derived TGF-β1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity. Immunity. 2020;53:1202-1214.e6 pubmed publisher
Kumar S, Wang X, Avuthu N, Bertolini T, Terhorst C, Guda C, et al. Role of Small Intestine and Gut Microbiome in Plant-Based Oral Tolerance for Hemophilia. Front Immunol. 2020;11:844 pubmed publisher
Cai B, Dongiovanni P, Corey K, Wang X, Shmarakov I, Zheng Z, et al. Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis. Cell Metab. 2020;31:406-421.e7 pubmed publisher
Minutti C, Modak R, MacDonald F, Li F, Smyth D, Dorward D, et al. A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation. Immunity. 2019;50:645-654.e6 pubmed publisher
Jayachandran R, Gumienny A, Bolinger B, Ruehl S, Lang M, Fucile G, et al. Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance while Maintaining Anti-Pathogen Immunity. Immunity. 2019;50:152-165.e8 pubmed publisher
Colliou N, Ge Y, Gong M, Zadeh M, Li J, Alonzo F, et al. Regulation of Th17 cells by P. UF1 against systemic Listeria monocytogenes infection. Gut Microbes. 2018;9:279-287 pubmed publisher
Wei C, Mei J, Tang L, Liu Y, Li D, Li M, et al. 1-Methyl-tryptophan attenuates regulatory T cells differentiation due to the inhibition of estrogen-IDO1-MRC2 axis in endometriosis. Cell Death Dis. 2016;7:e2489 pubmed publisher
Gubser C, Schmaler M, Rossi S, Palmer E. Monoclonal regulatory T cells provide insights into T cell suppression. Sci Rep. 2016;6:25758 pubmed publisher
Mukhopadhyay D, Mukherjee S, Roy S, Dalton J, Kundu S, Sarkar A, et al. M2 Polarization of Monocytes-Macrophages Is a Hallmark of Indian Post Kala-Azar Dermal Leishmaniasis. PLoS Negl Trop Dis. 2015;9:e0004145 pubmed publisher
Furuya Y, Furuya A, Roberts S, Sanfilippo A, Salmon S, Metzger D. Prevention of Influenza Virus-Induced Immunopathology by TGF-β Produced during Allergic Asthma. PLoS Pathog. 2015;11:e1005180 pubmed publisher
product information
Antigen :
LAP
Apps. Abbrev. :
FC
Cat # :
141405
Clone :
TW7-16B4
Item :
APC anti-mouse LAP (TGF-β1)
Isotype :
Mouse IgG1, κ
Other Names :
Latency Associated Peptide (LAP), Transforming growth factor-beta 1 (TGF-b1), TGFB1, DPD1, TGF-beta1
Size :
25 μg
Price (USD) :
137 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Immunogen :
Mouse Tgfb1 -transduced P3U1 cells
Application Notes :
Clone TW7-16B4 has been reported to not cross-react with bovine LAP.^2 Several anti-LAP antibody clones have been compared and characterized for their LAP reactivity.^2 TW7-16B4 recognizes recombinant LAP, latent TGF-β, and pro-TGF-β.Additional reported applications (for relevant formats) include: Western blotting^1 and immunoprecipitation^1.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA