product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse LAP (TGF-β1)
catalog :
141404
quantity :
100 μg
price :
347 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
TW7-16B4
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 11
Reference
Li J, Yao Z, Liu X, Duan R, Yi X, Ayoub A, et al. TGFβ1+CCR5+ neutrophil subset increases in bone marrow and causes age-related osteoporosis in male mice. Nat Commun. 2023;14:159 pubmed publisher
Lin G, Zhang L, Yan Z, Jiang W, Wu B, Li D, et al. Identification of heterogeneous subsets of aortic interleukin-17A-expressing CD4+ T cells in atherosclerotic mice. Int J Immunopathol Pharmacol. 2022;36:3946320221117933 pubmed publisher
Gabriely G, Ma D, Siddiqui S, Sun L, Skillin N, Abou El Hassan H, et al. Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells. iScience. 2021;24:103347 pubmed publisher
Hinterbrandner M, Rubino V, Stoll C, Forster S, Schnüriger N, Radpour R, et al. Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells. JCI Insight. 2021;6: pubmed publisher
Lain xe9 A, Labiad O, Hernandez Vargas H, This S, Sanlaville A, L xe9 on S, et al. Regulatory T cells promote cancer immune-escape through integrin αvβ8-mediated TGF-β activation. Nat Commun. 2021;12:6228 pubmed publisher
Turner J, Stephen Victor E, Wang S, Rivas M, Abdel Gadir A, Harb H, et al. Regulatory T Cell-Derived TGF-β1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity. Immunity. 2020;53:1202-1214.e6 pubmed publisher
Timilshina M, You Z, Lacher S, Acharya S, Jiang L, Kang Y, et al. Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells. Cell Rep. 2019;27:2948-2961.e7 pubmed publisher
Joly M, Martin R, Mitra Kaushik S, Phillips L, D Angona A, Richards S, et al. Transient low-dose methotrexate generates B regulatory cells that mediate antigen-specific tolerance to alglucosidase alfa. J Immunol. 2014;193:3947-58 pubmed publisher
Bedke T, Iannitti R, De Luca A, Giovannini G, Fallarino F, Berges C, et al. Distinct and complementary roles for Aspergillus fumigatus-specific Tr1 and Foxp3+ regulatory T cells in humans and mice. Immunol Cell Biol. 2014;92:659-70 pubmed publisher
Mercadante A, Perobelli S, Alves A, Gonçalves Silva T, Mello W, Gomes Santos A, et al. Oral combined therapy with probiotics and alloantigen induces B cell-dependent long-lasting specific tolerance. J Immunol. 2014;192:1928-37 pubmed publisher
Gong Y, Wang Z, Liang Z, Duan H, Ouyang L, Yu Q, et al. Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells. PLoS ONE. 2012;7:e47435 pubmed publisher
product information
Antigen :
LAP
Apps. Abbrev. :
FC
Cat # :
141404
Clone :
TW7-16B4
Item :
PE anti-mouse LAP (TGF-β1)
Isotype :
Mouse IgG1, κ
Other Names :
Latency Associated Peptide (LAP), Transforming growth factor-beta 1 (TGF-b1), TGFB1, DPD1, TGF-beta1
Size :
100 μg
Price (USD) :
347 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Immunogen :
Mouse Tgfb1 -transduced P3U1 cells
Application Notes :
Clone TW7-16B4 has been reported to not cross-react with bovine LAP.^2 Several anti-LAP antibody clones have been compared and characterized for their LAP reactivity.^2 TW7-16B4 recognizes recombinant LAP, latent TGF-β, and pro-TGF-β.Additional reported applications (for relevant formats) include: Western blotting^1 and immunoprecipitation^1.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA