product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-mouse CD64 (FcγRI)
catalog :
139305
quantity :
25 μg
price :
107 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
X54-5/7.1
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 60
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig ev2-4
Andriessen E, Binet F, Fournier F, Hata M, Dejda A, Mawambo G, et al. Myeloid-resident neuropilin-1 promotes choroidal neovascularization while mitigating inflammation. EMBO Mol Med. 2021;13:e11754 pubmed publisher
  • flow cytometry; mouse; loading ...; fig e10a
Alspach E, Lussier D, Miceli A, Kizhvatov I, DuPage M, Luoma A, et al. MHC-II neoantigens shape tumour immunity and response to immunotherapy. Nature. 2019;574:696-701 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s19a
Normand S, Waldschmitt N, Neerincx A, Martinez Torres R, Chauvin C, Couturier Maillard A, et al. Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens. Nat Commun. 2018;9:5338 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig s1a
Barthels C, Ogrinc A, Steyer V, Meier S, Simon F, Wimmer M, et al. CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis. Nat Commun. 2017;8:14715 pubmed publisher
  • flow cytometry; mouse; fig s2
Ermert D, Shaughnessy J, Joeris T, Kaplan J, Pang C, Kurt Jones E, et al. Virulence of Group A Streptococci Is Enhanced by Human Complement Inhibitors. PLoS Pathog. 2015;11:e1005043 pubmed publisher
Spix B, Butz E, Chen C, Rosato A, Tang R, Jeridi A, et al. Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice. Nat Commun. 2022;13:318 pubmed publisher
Marangoni F, Zhakyp A, Corsini M, Geels S, Carrizosa E, Thelen M, et al. Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop. Cell. 2021;184:3998-4015.e19 pubmed publisher
Avgustinova A, Laudanna C, Pascual García M, Rovira Q, Djurec M, Castellanos A, et al. Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development. Cell Stem Cell. 2021;: pubmed publisher
Clark J, Christian D, Gullicksrud J, Perry J, Park J, Jacquet M, et al. IL-33 promotes innate lymphoid cell-dependent IFN-γ production required for innate immunity to Toxoplasma gondii. elife. 2021;10: pubmed publisher
Dikiy S, Li J, Bai L, Jiang M, Janke L, Zong X, et al. A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance. Immunity. 2021;54:931-946.e11 pubmed publisher
Earnest J, Holmes A, Basore K, Mack M, Fremont D, Diamond M. The mechanistic basis of protection by non-neutralizing anti-alphavirus antibodies. Cell Rep. 2021;35:108962 pubmed publisher
Omori S, Tsugita M, Hoshikawa Y, Morita M, Ito F, Yamaguchi S, et al. Tim4 recognizes carbon nanotubes and mediates phagocytosis leading to granuloma formation. Cell Rep. 2021;34:108734 pubmed publisher
Maisonneuve C, Tsang D, Foerster E, Robert L, Mukherjee T, Prescott D, et al. Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells. Cell Rep. 2021;34:108677 pubmed publisher
Stacy A, Andrade Oliveira V, McCulloch J, Hild B, Oh J, Pérez Chaparro P, et al. Infection trains the host for microbiota-enhanced resistance to pathogens. Cell. 2021;184:615-627.e17 pubmed publisher
Kim J, Kolesnikov M, Peled Hajaj S, Scheyltjens I, Xia Y, Trzebanski S, et al. A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages. Immunity. 2021;54:176-190.e7 pubmed publisher
Hildreth A, Riggan L, O Sullivan T. CRISPR-Cas9 Ribonucleoprotein-Mediated Genomic Editing in Primary Innate Immune Cells. STAR Protoc. 2020;1:100113 pubmed publisher
Guendel F, Kofoed Branzk M, Gronke K, Tizian C, Witkowski M, Cheng H, et al. Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues. Immunity. 2020;53:1015-1032.e8 pubmed publisher
Liu Z, Gu Y, Shin A, Zhang S, Ginhoux F. Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry. STAR Protoc. 2020;1:100029 pubmed publisher
Rothchild A, Mai D, Aderem A, Diercks A. Flow Cytometry Analysis and Fluorescence-activated Cell Sorting of Myeloid Cells from Lung and Bronchoalveolar Lavage Samples from Mycobacterium tuberculosis-infected Mice. Bio Protoc. 2020;10: pubmed publisher
Si Y, Tian Q, Zhao F, Kelly S, Shores L, Camacho D, et al. Adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and TH17 responses. Sci Adv. 2020;6:eaba0995 pubmed publisher
Markworth J, Brown L, Lim E, Floyd C, Larouche J, Castor Macias J, et al. Resolvin D1 supports skeletal myofiber regeneration via actions on myeloid and muscle stem cells. JCI Insight. 2020;5: pubmed publisher
Choi E, Lee M, Song J, Kim K, Lee J, Yang J, et al. Fas mutation reduces obesity by increasing IL-4 and IL-10 expression and promoting white adipose tissue browning. Sci Rep. 2020;10:12001 pubmed publisher
Joshi J, Joshi B, Rochford I, Rayees S, Akhter M, Baweja S, et al. SPHK2-Generated S1P in CD11b+ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages. Cell Rep. 2020;30:4096-4109.e5 pubmed publisher
Sencio V, Barthelemy A, Tavares L, Machado M, Soulard D, Cuinat C, et al. Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production. Cell Rep. 2020;30:2934-2947.e6 pubmed publisher
Aegerter H, Kulikauskaite J, Crotta S, Patel H, Kelly G, Hessel E, et al. Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection. Nat Immunol. 2020;21:145-157 pubmed publisher
Huang W, Wu C, Hsu Y, Chang C. Effect of hyperthermia on improving neutrophil restoration after intraperitoneal chemotherapy. Int J Hyperthermia. 2019;36:1255-1263 pubmed publisher
Leruste A, Tosello J, Ramos R, Tauziède Espariat A, Brohard S, Han Z, et al. Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors. Cancer Cell. 2019;36:597-612.e8 pubmed publisher
Brown C, Gudjonson H, Pritykin Y, Deep D, Lavallée V, Mendoza A, et al. Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity. Cell. 2019;179:846-863.e24 pubmed publisher
Liu Z, Gu Y, Chakarov S, Blériot C, Kwok I, Chen X, et al. Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells. Cell. 2019;178:1509-1525.e19 pubmed publisher
Bradley K, Finsterbusch K, Schnepf D, Crotta S, Llorian M, Davidson S, et al. Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection. Cell Rep. 2019;28:245-256.e4 pubmed publisher
Camara A, Cordeiro O, Alloush F, Sponsel J, Chypre M, Onder L, et al. Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche. Immunity. 2019;50:1467-1481.e6 pubmed publisher
Qi X, Li F, Wu Y, Cheng C, Han P, Wang J, et al. Optimization of 4-1BB antibody for cancer immunotherapy by balancing agonistic strength with FcγR affinity. Nat Commun. 2019;10:2141 pubmed publisher
Zhang S, Wang M, Wang X, Li H, Tang H, Li X. Salmonella infection leads to severe intestinal inflammation and increased CD4+FoxP3+ Treg cells in streptozotocin‑induced hyperglycemic mice. Mol Med Rep. 2019;19:5377-5385 pubmed publisher
Wang K, Chu K, Batista N, Watts T. Conserved and Differential Features of TNF Superfamily Ligand Expression on APC Subsets over the Course of a Chronic Viral Infection in Mice. Immunohorizons. 2018;2:407-417 pubmed publisher
Chan Y, Teo T, Utt A, Tan J, Amrun S, Abu Bakar F, et al. Mutating chikungunya virus non-structural protein produces potent live-attenuated vaccine candidate. EMBO Mol Med. 2019;11: pubmed publisher
de Tymowski C, Heming N, Correia M, Abbad L, Chavarot N, Le Stang M, et al. CD89 Is a Potent Innate Receptor for Bacteria and Mediates Host Protection from Sepsis. Cell Rep. 2019;27:762-775.e5 pubmed publisher
Silva H, Bafica A, Rodrigues Luiz G, Chi J, Santos P, Reis B, et al. Vasculature-associated fat macrophages readily adapt to inflammatory and metabolic challenges. J Exp Med. 2019;216:786-806 pubmed publisher
Zwick M, Ulas T, Cho Y, Ried C, Grosse L, Simon C, et al. Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8+ Dendritic Cells. Front Immunol. 2019;10:222 pubmed publisher
Andersen T, Huszthy P, Gopalakrishnan R, Jacobsen J, Fauskanger M, Tveita A, et al. Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules. NPJ Vaccines. 2019;4:9 pubmed publisher
Bachus H, Kaur K, Papillion A, Marquez Lago T, Yu Z, Ballesteros Tato A, et al. Impaired Tumor-Necrosis-Factor-α-driven Dendritic Cell Activation Limits Lipopolysaccharide-Induced Protection from Allergic Inflammation in Infants. Immunity. 2019;50:225-240.e4 pubmed publisher
Gubin M, Esaulova E, Ward J, Malkova O, Runci D, Wong P, et al. High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy. Cell. 2018;175:1014-1030.e19 pubmed publisher
Cohen S, Gern B, Delahaye J, Adams K, Plumlee C, Winkler J, et al. Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination. Cell Host Microbe. 2018;24:439-446.e4 pubmed publisher
Steuerman Y, Cohen M, Peshes Yaloz N, Valadarsky L, Cohn O, David E, et al. Dissection of Influenza Infection In Vivo by Single-Cell RNA Sequencing. Cell Syst. 2018;6:679-691.e4 pubmed publisher
Tippimanchai D, Nolan K, Poczobutt J, Verzosa G, Li H, Scarborough H, et al. Adenoviral vectors transduce alveolar macrophages in lung cancer models. Oncoimmunology. 2018;7:e1438105 pubmed publisher
Privratsky J, Zhang J, Lu X, Rudemiller N, Wei Q, Yu Y, et al. Interleukin 1 receptor (IL-1R1) activation exacerbates toxin-induced acute kidney injury. Am J Physiol Renal Physiol. 2018;315:F682-F691 pubmed publisher
Barbet G, Sander L, Geswell M, Leonardi I, Cerutti A, Iliev I, et al. Sensing Microbial Viability through Bacterial RNA Augments T Follicular Helper Cell and Antibody Responses. Immunity. 2018;48:584-598.e5 pubmed publisher
Lagares D, Santos A, Grasberger P, Liu F, Probst C, Rahimi R, et al. Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis. Sci Transl Med. 2017;9: pubmed publisher
Clemente Casares X, Hosseinzadeh S, Barbu I, Dick S, Macklin J, Wang Y, et al. A CD103+ Conventional Dendritic Cell Surveillance System Prevents Development of Overt Heart Failure during Subclinical Viral Myocarditis. Immunity. 2017;47:974-989.e8 pubmed publisher
Chang Y, Wang K, Chu K, Clouthier D, Tran A, Torres Perez M, et al. Dichotomous Expression of TNF Superfamily Ligands on Antigen-Presenting Cells Controls Post-priming Anti-viral CD4+ T Cell Immunity. Immunity. 2017;47:943-958.e9 pubmed publisher
Martin T, Möglich A, Felix I, Förtsch C, Rittlinger A, Palmer A, et al. Rho-inhibiting C2IN-C3 fusion toxin inhibits chemotactic recruitment of human monocytes ex vivo and in mice in vivo. Arch Toxicol. 2018;92:323-336 pubmed publisher
Baratin M, Simon L, Jorquera A, Ghigo C, Dembele D, Nowak J, et al. T Cell Zone Resident Macrophages Silently Dispose of Apoptotic Cells in the Lymph Node. Immunity. 2017;47:349-362.e5 pubmed publisher
Domínguez Andrés J, Feo Lucas L, Minguito de la Escalera M, Gonzalez L, López Bravo M, Ardavin C. Inflammatory Ly6Chigh Monocytes Protect against Candidiasis through IL-15-Driven NK Cell/Neutrophil Activation. Immunity. 2017;46:1059-1072.e4 pubmed publisher
Hulsmans M, Clauss S, Xiao L, Aguirre A, King K, Hanley A, et al. Macrophages Facilitate Electrical Conduction in the Heart. Cell. 2017;169:510-522.e20 pubmed publisher
Morikawa M, Tsujibe S, Kiyoshima Shibata J, Watanabe Y, Kato Nagaoka N, Shida K, et al. Microbiota of the Small Intestine Is Selectively Engulfed by Phagocytes of the Lamina Propria and Peyer's Patches. PLoS ONE. 2016;11:e0163607 pubmed publisher
Meliopoulos V, Van De Velde L, Van De Velde N, Karlsson E, Neale G, Vogel P, et al. An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens. PLoS Pathog. 2016;12:e1005804 pubmed publisher
Qayum A, Paranjape A, Abebayehu D, Kolawole E, Haque T, McLeod J, et al. IL-10-Induced miR-155 Targets SOCS1 To Enhance IgE-Mediated Mast Cell Function. J Immunol. 2016;196:4457-67 pubmed publisher
Terhorst D, Chelbi R, Wohn C, Malosse C, Tamoutounour S, Jorquera A, et al. Dynamics and Transcriptomics of Skin Dendritic Cells and Macrophages in an Imiquimod-Induced, Biphasic Mouse Model of Psoriasis. J Immunol. 2015;195:4953-61 pubmed publisher
Calderon B, Carrero J, Ferris S, Sojka D, Moore L, Epelman S, et al. The pancreas anatomy conditions the origin and properties of resident macrophages. J Exp Med. 2015;212:1497-512 pubmed publisher
Zhou Q, Ho A, Schlitzer A, Tang Y, Wong K, Wong F, et al. GM-CSF-licensed CD11b+ lung dendritic cells orchestrate Th2 immunity to Blomia tropicalis. J Immunol. 2014;193:496-509 pubmed publisher
Ozeri E, Mizrahi M, Shahaf G, Lewis E. ?-1 antitrypsin promotes semimature, IL-10-producing and readily migrating tolerogenic dendritic cells. J Immunol. 2012;189:146-53 pubmed publisher
product information
Antigen :
CD64
Apps. Abbrev. :
FC
Cat # :
139305
Clone :
X54-5/7.1
Item :
APC anti-mouse CD64 (FcγRI)
Isotype :
Mouse IgG1, κ
Other Names :
FcRI
Size :
25 μg
Price (USD) :
107 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Immunogen :
BALB/c mouse FcγRI-human IgG Fc fusion protein.
Application Notes :
The X54-5/7.1 antibody reacts with mouse strains carrying CD64a and b alleles but not CD64d. X54-5/7.1 recognizes a conformational determinant formed between domains 2 and 3. Additional reported application (for relevant formats) include: immunoprecipitation^1, and spatial biology (IBEX)^5,6. Clone X54-5/7.1 is not found to be useful for Western blots^1.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA