product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE/Cyanine7 anti-mouse/human KLRG1 (MAFA)
catalog :
138415
quantity :
25 μg
price :
124 USD
clonality :
monoclonal
host :
Syrian golden hamster
conjugate :
PE/Cy7
clone name :
2F1/KLRG1
reactivity :
human, mouse
application :
flow cytometry
more info or order :
citations: 42
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:200; loading ...; fig s7b
Ercolano G, Gomez Cadena A, Dumauthioz N, Vanoni G, Kreutzfeldt M, Wyss T, et al. PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions. Nat Commun. 2021;12:2538 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s7e
van der Weyden L, Arends M, Campbell A, Bald T, Wardle Jones H, Griggs N, et al. Genome-wide in vivo screen identifies novel host regulators of metastatic colonization. Nature. 2017;541:233-236 pubmed publisher
Corria Osorio J, Carmona S, Stefanidis E, Andreatta M, Ortiz Miranda Y, Muller T, et al. Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8+ T cells. Nat Immunol. 2023;24:869-883 pubmed publisher
Spath S, Roan F, Presnell S, H xf6 llbacher B, Ziegler S. Profiling of Tregs across tissues reveals plasticity in ST2 expression and hierarchies in tissue-specific phenotypes. iScience. 2022;25:104998 pubmed publisher
Pfenninger P, Yerly L, Abe J. Naïve Primary Mouse CD8+ T Cells Retain In Vivo Immune Responsiveness After Electroporation-Based CRISPR/Cas9 Genetic Engineering. Front Immunol. 2022;13:777113 pubmed publisher
Dolfi B, Gallerand A, Firulyova M, Xu Y, Merlin J, Dumont A, et al. Unravelling the sex-specific diversity and functions of adrenal gland macrophages. Cell Rep. 2022;39:110949 pubmed publisher
Grebinoski S, Zhang Q, Cillo A, Manne S, Xiao H, Brunazzi E, et al. Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3. Nat Immunol. 2022;23:868-877 pubmed publisher
Parga Vidal L, Taggenbrock R, Beumer Chuwonpad A, Aglmous H, Kragten N, Behr F, et al. Hobit and Blimp-1 regulate TRM abundance after LCMV infection by suppressing tissue exit pathways of TRM precursors. Eur J Immunol. 2022;52:1095-1111 pubmed publisher
Cautivo K, Matatia P, Lizama C, Mroz N, Dahlgren M, Yu X, et al. Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation. Immunity. 2022;55:254-271.e7 pubmed publisher
Koenig A, Vaeth M, Xiao Y, Chiarolla C, Erapaneedi R, Klein M, et al. NFATc1/αA and Blimp-1 Support the Follicular and Effector Phenotype of Tregs. Front Immunol. 2021;12:791100 pubmed publisher
Jakic B, Kimpel J, Olson W, Labi V, Hermann Kleiter N. Bacterial Infection with Listeria monocytogenes in Mice and Subsequent Analysis of Antigen-Specific CD8 T Cell Responses. Bio Protoc. 2021;11:e4247 pubmed publisher
Bourque J, Opejin A, Surnov A, Iberg C, Gross C, Jain R, et al. Landscape of Hopx expression in cells of the immune system. Heliyon. 2021;7:e08311 pubmed publisher
Fiege J, Block K, Pierson M, Nanda H, Shepherd F, Mickelson C, et al. Mice with diverse microbial exposure histories as a model for preclinical vaccine testing. Cell Host Microbe. 2021;29:1815-1827.e6 pubmed publisher
Klarquist J, Cross E, Thompson S, Willett B, Aldridge D, Caffrey Carr A, et al. B cells promote CD8 T cell primary and memory responses to subunit vaccines. Cell Rep. 2021;36:109591 pubmed publisher
Chen Y, Zander R, Wu X, Schauder D, Kasmani M, Shen J, et al. BATF regulates progenitor to cytolytic effector CD8+ T cell transition during chronic viral infection. Nat Immunol. 2021;22:996-1007 pubmed publisher
Li C, Wang G, Sivasami P, Ramirez R, Zhang Y, Benoist C, et al. Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity. Cell Metab. 2021;33:1610-1623.e5 pubmed publisher
Pardy R, Valbon S, Cordeiro B, Krawczyk C, Richer M. An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways. Nat Commun. 2021;12:4051 pubmed publisher
Gern B, Adams K, Plumlee C, Stoltzfus C, Shehata L, Moguche A, et al. TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma. Cell Host Microbe. 2021;29:594-606.e6 pubmed publisher
Frost J, Tan T, Abbas M, Wideman S, Bonadonna M, Stoffel N, et al. Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to Vaccination and Infection. Med. 2021;2:164-179.e12 pubmed publisher
She L, Barrera G, Yan L, Alanazi H, Brooks E, Dube P, et al. STING activation in alveolar macrophages and group 2 innate lymphoid cells suppresses IL-33-driven type 2 immunopathology. JCI Insight. 2021;6: pubmed publisher
Hildreth A, Riggan L, O Sullivan T. CRISPR-Cas9 Ribonucleoprotein-Mediated Genomic Editing in Primary Innate Immune Cells. STAR Protoc. 2020;1:100113 pubmed publisher
Mogilenko D, Shpynov O, Andhey P, Arthur L, Swain A, Esaulova E, et al. Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging. Immunity. 2021;54:99-115.e12 pubmed publisher
Sun Y, Preiss N, Valenteros K, Kamal Y, Usherwood Y, Frost H, et al. Zbtb20 Restrains CD8 T Cell Immunometabolism and Restricts Memory Differentiation and Antitumor Immunity. J Immunol. 2020;205:2649-2666 pubmed publisher
Behr F, Beumer Chuwonpad A, Kragten N, Wesselink T, Stark R, van Gisbergen K. Circulating memory CD8+ T cells are limited in forming CD103+ tissue-resident memory T cells at mucosal sites after reinfection. Eur J Immunol. 2021;51:151-166 pubmed publisher
JAISWAL A, Makhija S, Stahr N, Sandey M, Suryawanshi A, Mishra A. Pyruvate kinase M2 in lung APCs regulates Alternaria-induced airway inflammation. Immunobiology. 2020;225:151956 pubmed publisher
He Y, Hong C, Yan E, Fletcher S, Zhu G, Yang M, et al. Self-assembled cGAMP-STINGΔTM signaling complex as a bioinspired platform for cGAMP delivery. Sci Adv. 2020;6:eaba7589 pubmed publisher
Ruhland M, Roberts E, Cai E, Mujal A, Marchuk K, Beppler C, et al. Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells. Cancer Cell. 2020;37:786-799.e5 pubmed publisher
Bharath L, Agrawal M, McCambridge G, Nicholas D, Hasturk H, Liu J, et al. Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation. Cell Metab. 2020;: pubmed publisher
Zander R, SCHAUDER D, Xin G, Nguyen C, Wu X, ZAJAC A, et al. CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer. Immunity. 2019;51:1028-1042.e4 pubmed publisher
Gupta S, Sharp R, Hofferek C, Kuai L, Dorn G, Wang J, et al. NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8+ T Cells. Cell Rep. 2019;29:1862-1877.e7 pubmed publisher
Gagnon J, Kageyama R, Shehata H, Fassett M, Mar D, Wigton E, et al. miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival. Cell Rep. 2019;28:2169-2181.e4 pubmed publisher
Nagashima H, Mahlakõiv T, Shih H, Davis F, Meylan F, Huang Y, et al. Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation. Immunity. 2019;51:682-695.e6 pubmed publisher
Contreras N, Sitnik K, Jeftic I, Coplen C, Cicin Sain L, Nikolich Zugich J. Life-long control of cytomegalovirus (CMV) by T resident memory cells in the adipose tissue results in inflammation and hyperglycemia. PLoS Pathog. 2019;15:e1007890 pubmed publisher
Wu J, Ma S, Sandhoff R, Ming Y, Hotz Wagenblatt A, Timmerman V, et al. Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness. Immunity. 2019;50:1218-1231.e5 pubmed publisher
Li C, DiSpirito J, Zemmour D, Spallanzani R, Kuswanto W, Benoist C, et al. TCR Transgenic Mice Reveal Stepwise, Multi-site Acquisition of the Distinctive Fat-Treg Phenotype. Cell. 2018;174:285-299.e12 pubmed publisher
Herndler Brandstetter D, Ishigame H, Shinnakasu R, Plajer V, Stecher C, Zhao J, et al. KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity. Immunity. 2018;48:716-729.e8 pubmed publisher
Beura L, Wijeyesinghe S, Thompson E, Macchietto M, Rosato P, Pierson M, et al. T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells. Immunity. 2018;48:327-338.e5 pubmed publisher
Ahrends T, Spanjaard A, Pilzecker B, Bąbała N, Bovens A, Xiao Y, et al. CD4+ T Cell Help Confers a Cytotoxic T Cell Effector Program Including Coinhibitory Receptor Downregulation and Increased Tissue Invasiveness. Immunity. 2017;47:848-861.e5 pubmed publisher
Zhang Y, Kurupati R, Liu L, Zhou X, Zhang G, Hudaihed A, et al. Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy. Cancer Cell. 2017;32:377-391.e9 pubmed publisher
Theurich S, Tsaousidou E, Hanssen R, Lempradl A, Mauer J, Timper K, et al. IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis. Cell Metab. 2017;26:171-184.e6 pubmed publisher
Joosten S, van Meijgaarden K, Del Nonno F, Baiocchini A, Petrone L, Vanini V, et al. Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment. PLoS Pathog. 2016;12:e1005687 pubmed publisher
de Alwis R, Bangs D, Angelo M, Cerpas C, Fernando A, Sidney J, et al. Immunodominant Dengue Virus-Specific CD8+ T Cell Responses Are Associated with a Memory PD-1+ Phenotype. J Virol. 2016;90:4771-4779 pubmed publisher
product information
Antigen :
KLRG1
Apps. Abbrev. :
FC
Cat # :
138415
Clone :
2F1/KLRG1
Item :
PE/Cyanine7 anti-mouse/human KLRG1 (MAFA)
Isotype :
Syrian Hamster IgG
Other Names :
MAFA, 2F1-Ag
Size :
25 μg
Price (USD) :
124 USD
Reactivity :
Mouse, Human
Clonality :
Monoclonal
Host :
Syrian Hamster
Conjugate/Tag/Label :
PE_CYANINE7
Immunogen :
IL-2 activated NK cells from C57BL/6 mice
Application Notes :
For successful staining of human cells, brighter fluorophore-antibody conjugates, such as PE, BV421™, or APC, are recommended.Additional reported applications (for relevant formats) include: Western Blotting^1.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA