product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 647 anti-mouse CD144 (VE-cadherin)
catalog :
138006
quantity :
100 μg
price :
411 USD
clonality :
monoclonal
host :
rat
conjugate :
AF647
clone name :
BV13
reactivity :
mouse
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 34
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...
Barcia Durán J, Lu T, Houghton S, Geng F, Schreiner R, Xiang J, et al. Endothelial Jak3 expression enhances pro-hematopoietic angiocrine function in mice. Commun Biol. 2021;4:406 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1l
Baryawno N, Przybylski D, Kowalczyk M, Kfoury Y, Severe N, Gustafsson K, et al. A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia. Cell. 2019;177:1915-1932.e16 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1a
Cunin P, Bouslama R, Machlus K, Martínez Bonet M, Lee P, Wactor A, et al. Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets. elife. 2019;8: pubmed publisher
Sa xe7 ma M, Matteini F, Mulaw M, Hageb A, Bogeska R, Sakk V, et al. Fast and high-fidelity in situ 3D imaging protocol for stem cells and niche components for mouse organs and tissues. STAR Protoc. 2022;3:101483 pubmed publisher
G xf3 mez Salinero J, Izzo F, Lin Y, Houghton S, Itkin T, Geng F, et al. Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction. Cell Stem Cell. 2022;29:593-609.e7 pubmed publisher
Zhang D, Gao X, Li H, Borger D, Wei Q, Yang E, et al. The microbiota regulates hematopoietic stem cell fate decisions by controlling iron availability in bone marrow. Cell Stem Cell. 2022;29:232-247.e7 pubmed publisher
Sharma G, Frei A, Narayanan J, Gasperetti T, Veley D, Amjad A, et al. Brain-derived neurotrophic factor promotes immune reconstitution following radiation injury via activation of bone marrow mesenchymal stem cells. PLoS ONE. 2021;16:e0259042 pubmed publisher
Grunewald M, Kumar S, Sharife H, Volinsky E, Gileles Hillel A, Licht T, et al. Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span. Science. 2021;373: pubmed publisher
Zhang J, Wu Q, Johnson C, Pham G, Kinder J, Olsson A, et al. In situ mapping identifies distinct vascular niches for myelopoiesis. Nature. 2021;590:457-462 pubmed publisher
Gao X, Zhang D, Xu C, Li H, Caron K, Frenette P. Nociceptive nerves regulate haematopoietic stem cell mobilization. Nature. 2021;589:591-596 pubmed publisher
Casadesús A, Deligne C, Diallo B, Sosa K, Josseaume N, Mesa C, et al. A rationally-engineered IL-2 improves the antitumor effect of anti-CD20 therapy. Oncoimmunology. 2020;9:1770565 pubmed publisher
Mirando A, Patil A, Rafie C, Christmas B, Pandey N, Stearns V, et al. Regulation of the tumor immune microenvironment and vascular normalization in TNBC murine models by a novel peptide. Oncoimmunology. 2020;9:1760685 pubmed publisher
Wei Q, Nakahara F, Asada N, Zhang D, Gao X, Xu C, et al. Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression. Dev Cell. 2020;53:503-513.e5 pubmed publisher
Ramanan D, Sefik E, Galván Peña S, Wu M, Yang L, Yang Z, et al. An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint. Cell. 2020;181:1276-1290.e13 pubmed publisher
Mohamed E, Sierra R, Trillo Tinoco J, Cao Y, Innamarato P, Payne K, et al. The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling. Immunity. 2020;52:668-682.e7 pubmed publisher
Lehmann G, Hanke Gogokhia C, Hu Y, Bareja R, Salfati Z, Ginsberg M, et al. Single-cell profiling reveals an endothelium-mediated immunomodulatory pathway in the eye choroid. J Exp Med. 2020;217: pubmed publisher
Himburg H, Roos M, Fang T, Zhang Y, Termini C, Schlussel L, et al. Chronic myeloid leukemia stem cells require cell-autonomous pleiotrophin signaling. J Clin Invest. 2020;130:315-328 pubmed publisher
Severe N, Karabacak N, Gustafsson K, Baryawno N, Courties G, Kfoury Y, et al. Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping. Cell Stem Cell. 2019;25:570-583.e7 pubmed publisher
Boulais P, Mizoguchi T, Zimmerman S, Nakahara F, Vivié J, Mar J, et al. The Majority of CD45- Ter119- CD31- Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors. Immunity. 2018;49:627-639.e6 pubmed publisher
Dravis C, Chung C, Lytle N, Herrera Valdez J, Luna G, Trejo C, et al. Epigenetic and Transcriptomic Profiling of Mammary Gland Development and Tumor Models Disclose Regulators of Cell State Plasticity. Cancer Cell. 2018;34:466-482.e6 pubmed publisher
Himburg H, Termini C, Schlussel L, Kan J, Li M, Zhao L, et al. Distinct Bone Marrow Sources of Pleiotrophin Control Hematopoietic Stem Cell Maintenance and Regeneration. Cell Stem Cell. 2018;23:370-381.e5 pubmed publisher
Xu C, Gao X, Wei Q, Nakahara F, Zimmerman S, Mar J, et al. Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow. Nat Commun. 2018;9:2449 pubmed publisher
Hirata Y, Furuhashi K, Ishii H, Li H, Pinho S, Ding L, et al. CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine. Cell Stem Cell. 2018;22:445-453.e5 pubmed publisher
Pinho S, Marchand T, Yang E, Wei Q, Nerlov C, Frenette P. Lineage-Biased Hematopoietic Stem Cells Are Regulated by Distinct Niches. Dev Cell. 2018;44:634-641.e4 pubmed publisher
Bowers E, Slaughter A, Frenette P, Kuick R, Pello O, Lucas D. Granulocyte-derived TNFα promotes vascular and hematopoietic regeneration in the bone marrow. Nat Med. 2018;24:95-102 pubmed publisher
Kedem A, Aelion Brauer A, Guo P, Wen D, Ding B, Lis R, et al. Activated ovarian endothelial cells promote early follicular development and survival. J Ovarian Res. 2017;10:64 pubmed publisher
Asada N, Kunisaki Y, Pierce H, Wang Z, Fernandez N, Birbrair A, et al. Differential cytokine contributions of perivascular haematopoietic stem cell niches. Nat Cell Biol. 2017;19:214-223 pubmed publisher
Poulos M, Ramalingam P, Gutkin M, Kleppe M, Ginsberg M, Crowley M, et al. Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis. Nat Commun. 2016;7:13829 pubmed publisher
Portal Celhay C, Tufariello J, Srivastava S, Zahra A, Klevorn T, Grace P, et al. Mycobacterium tuberculosis EsxH inhibits ESCRT-dependent CD4+ T-cell activation. Nat Microbiol. 2016;2:16232 pubmed publisher
Kostadinova E, Chaput C, Gutbier B, Lippmann J, Sander L, Mitchell T, et al. NLRP3 protects alveolar barrier integrity by an inflammasome-independent increase of epithelial cell adherence. Sci Rep. 2016;6:30943 pubmed publisher
Mizoguchi T, Pinho S, Ahmed J, Kunisaki Y, Hanoun M, Mendelson A, et al. Osterix marks distinct waves of primitive and definitive stromal progenitors during bone marrow development. Dev Cell. 2014;29:340-9 pubmed publisher
Renner B, Klawitter J, Goldberg R, McCullough J, Ferreira V, Cooper J, et al. Cyclosporine induces endothelial cell release of complement-activating microparticles. J Am Soc Nephrol. 2013;24:1849-62 pubmed publisher
Gordon Keylock S, Sobiesiak M, Rybtsov S, Moore K, Medvinsky A. Mouse extraembryonic arterial vessels harbor precursors capable of maturing into definitive HSCs. Blood. 2013;122:2338-45 pubmed publisher
Rybtsov S, Sobiesiak M, Taoudi S, Souilhol C, Senserrich J, Liakhovitskaia A, et al. Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region. J Exp Med. 2011;208:1305-15 pubmed publisher
product information
Antigen :
CD144
Apps. Abbrev. :
FC
Cat # :
138006
Clone :
BV13
Item :
Alexa Fluor® 647 anti-mouse CD144 (VE-cadherin)
Isotype :
Rat IgG1, κ
Other Names :
Vascular endothelial-cadherin
Size :
100 μg
Price (USD) :
411 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
A647
Immunogen :
VE-cadherin-Ig fusion protein
Application Notes :
Clone BV13 recognizes an epitope between aa 45 and 56, and has a binding affinity of 5-15 nM^5. Additional reported applications (for relevant formats) include: Western blotting^1, blocking of cell interactions in vivo^1, and immunofluorescence microscopy^ staining^4;.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA