product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-mouse CD335 (NKp46)
catalog :
137611
quantity :
125 μL
price :
204 USD
clonality :
monoclonal
host :
rat
conjugate :
BV421
clone name :
29A1.4
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 31
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:80; loading ...; fig 6e
Wolpaw A, Grossmann L, Dessau J, Dong M, Aaron B, Brafford P, et al. Epigenetic state determines inflammatory sensing in neuroblastoma. Proc Natl Acad Sci U S A. 2022;119: pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig s4d
Abreu Mota T, Hagen K, Cooper K, Jahrling P, Tan G, Wirblich C, et al. Non-neutralizing antibodies elicited by recombinant Lassa-Rabies vaccine are critical for protection against Lassa fever. Nat Commun. 2018;9:4223 pubmed publisher
Wu Z, Thierry K, Bachy S, Zhang X, Gamradt P, Hernandez Vargas H, et al. Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer. EMBO Rep. 2023;24:e56524 pubmed publisher
Luo B, Zhang S, Tan D, Yu X, Lin J, Wang M. Anlotinib Benefits the αPDL1 Immunotherapy by Activating ROS/JNK/AP-1 Pathway to Upregulate PDL1 Expression in Colorectal Cancer. Oxid Med Cell Longev. 2022;2022:8965903 pubmed publisher
Kennedy E, Denslow A, Hewett J, Kong L, De Almeida A, Bryant J, et al. Development of intravenously administered synthetic RNA virus immunotherapy for the treatment of cancer. Nat Commun. 2022;13:5907 pubmed publisher
Wagner A, Kadri N, Tibbitt C, van de Ven K, Bagawath Singh S, Oliinyk D, et al. PD-1 expression on mouse intratumoral NK cells and its effects on NK cell phenotype. iScience. 2022;25:105137 pubmed publisher
Mugarza E, Van Maldegem F, Boumelha J, Moore C, Rana S, Llorian Sopena M, et al. Therapeutic KRASG12C inhibition drives effective interferon-mediated antitumor immunity in immunogenic lung cancers. Sci Adv. 2022;8:eabm8780 pubmed publisher
Serra M, Di Matteo M, Serneels J, Pal R, Cafarello S, Lanza M, et al. Deletion of Lactate Dehydrogenase-A Impairs Oncogene-Induced Mouse Hepatocellular Carcinoma Development. Cell Mol Gastroenterol Hepatol. 2022;14:609-624 pubmed publisher
Dolfi B, Gallerand A, Firulyova M, Xu Y, Merlin J, Dumont A, et al. Unravelling the sex-specific diversity and functions of adrenal gland macrophages. Cell Rep. 2022;39:110949 pubmed publisher
Kissiov D, Ethell A, Chen S, Wolf N, Zhang C, Dang S, et al. Binary outcomes of enhancer activity underlie stable random monoallelic expression. elife. 2022;11: pubmed publisher
Ghaffari S, Upchurch Ange K, Gimlin S, Tripathi T, Sluijter M, Middelburg J, et al. A Single-Domain TCR-like Antibody Selective for the Qa-1b/Qdm Peptide Complex Enhances Tumoricidal Activity of NK Cells via Blocking the NKG2A Immune Checkpoint. J Immunol. 2022;208:2246-2255 pubmed publisher
Zindl C, Witte S, Laufer V, Gao M, Yue Z, Janowski K, et al. A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts. Immunity. 2022;55:494-511.e11 pubmed publisher
Shen J, Qiu Z, Wu Q, Zhang G, Harris R, Sun D, et al. A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells. Mol Cell. 2022;82:1123-1139.e8 pubmed publisher
Alikhanyan K, Chen Y, Somogyi K, Kraut S, Sotillo R. Mad2 Induced Aneuploidy Contributes to Eml4-Alk Driven Lung Cancer by Generating an Immunosuppressive Environment. Cancers (Basel). 2021;13: pubmed publisher
Wang X, Tokheim C, Gu S, Wang B, Tang Q, Li Y, et al. In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target. Cell. 2021;184:5357-5374.e22 pubmed publisher
Pierson M, Merley A, Hamilton S. Generating Mice with Diverse Microbial Experience. Curr Protoc. 2021;1:e53 pubmed publisher
Shen J, Qiu Z, Wu Q, Finlay D, Garcia G, Sun D, et al. FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells. Cell. 2021;184:352-369.e23 pubmed publisher
Martomo S, Lu D, Polonskaya Z, Luna X, Zhang Z, Feldstein S, et al. Single-Dose Anti-PD-L1/IL-15 Fusion Protein KD033 Generates Synergistic Antitumor Immunity with Robust Tumor-Immune Gene Signatures and Memory Responses. Mol Cancer Ther. 2021;20:347-356 pubmed publisher
Goh W, Scheer S, Jackson J, Hediyeh Zadeh S, Delconte R, Schuster I, et al. Hhex Directly Represses BIM-Dependent Apoptosis to Promote NK Cell Development and Maintenance. Cell Rep. 2020;33:108285 pubmed publisher
Kaya B, Doñas C, Wuggenig P, Diaz O, Morales R, Melhem H, et al. Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1+ Macrophages Regulates Intestinal Homeostasis. Cell Rep. 2020;32:107979 pubmed publisher
LaMarche N, Kane H, Kohlgruber A, Dong H, Lynch L, Brenner M. Distinct iNKT Cell Populations Use IFNγ or ER Stress-Induced IL-10 to Control Adipose Tissue Homeostasis. Cell Metab. 2020;32:243-258.e6 pubmed publisher
Muthalagu N, Monteverde T, Raffo Iraolagoitia X, Wiesheu R, Whyte D, Hedley A, et al. Repression of the Type I Interferon Pathway Underlies MYC- and KRAS-Dependent Evasion of NK and B Cells in Pancreatic Ductal Adenocarcinoma. Cancer Discov. 2020;10:872-887 pubmed publisher
Alikhanyan K, Chen Y, Kraut S, Sotillo R. Targeting alveolar macrophages shows better treatment response than deletion of interstitial macrophages in EGFR mutant lung adenocarcinoma. Immun Inflamm Dis. 2020;8:181-187 pubmed publisher
Lai N, Musser M, Pinho Ribeiro F, Baral P, Jacobson A, Ma P, et al. Gut-Innervating Nociceptor Neurons Regulate Peyer's Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense. Cell. 2020;180:33-49.e22 pubmed publisher
Maluski M, Ghosh A, Herbst J, Scholl V, Baumann R, Huehn J, et al. Chimeric antigen receptor-induced BCL11B suppression propagates NK-like cell development. J Clin Invest. 2019;129:5108-5122 pubmed publisher
Huggins M, Sjaastad F, Pierson M, Kucaba T, Swanson W, Staley C, et al. Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization. Cell Rep. 2019;28:1729-1743.e5 pubmed publisher
Ponzetta A, Carriero R, Carnevale S, Barbagallo M, Molgora M, Perucchini C, et al. Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors. Cell. 2019;178:346-360.e24 pubmed publisher
Sivick K, Desbien A, Glickman L, Reiner G, Corrales L, Surh N, et al. Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity. Cell Rep. 2018;25:3074-3085.e5 pubmed publisher
Burrack K, Huggins M, Taras E, Dougherty P, Henzler C, Yang R, et al. Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells. Immunity. 2018;48:760-772.e4 pubmed publisher
Theurich S, Tsaousidou E, Hanssen R, Lempradl A, Mauer J, Timper K, et al. IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis. Cell Metab. 2017;26:171-184.e6 pubmed publisher
Guerriero J, Ditsworth D, Catanzaro J, Sabino G, Furie M, Kew R, et al. DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity. J Immunol. 2011;186:3517-26 pubmed publisher
product information
Antigen :
CD335
Apps. Abbrev. :
FC
Cat # :
137611
Clone :
29A1.4
Item :
Brilliant Violet 421™ anti-mouse CD335 (NKp46)
Isotype :
Rat IgG2a, κ
Other Names :
NKp46, NCR1
Size :
125 μL
Price (USD) :
204 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
BV421
Immunogen :
NKP46-IgG1 Fc fusion protein
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of frozen tissue sections^1,2 and in vitro activation of NK cells^1.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA