product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse CD335 (NKp46)
catalog :
137604
quantity :
100 μg
price :
286 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
29A1.4
reactivity :
mouse
application :
flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 40
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s19c
Stewart B, Ferdinand J, Young M, Mitchell T, Loudon K, Riding A, et al. Spatiotemporal immune zonation of the human kidney. Science. 2019;365:1461-1466 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Almeida F, Tognarelli S, Marcais A, Kueh A, Friede M, Liao Y, et al. A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets. Oncoimmunology. 2018;7:e1475875 pubmed publisher
  • flow cytometry; mouse; fig 2d
Bar On Y, Charpak Amikam Y, Glasner A, Isaacson B, Duev Cohen A, Tsukerman P, et al. NKp46 Recognizes the Sigma1 Protein of Reovirus: Implications for Reovirus-Based Cancer Therapy. J Virol. 2017;91: pubmed publisher
  • flow cytometry; mouse; 1:20; loading ...; fig 2a
Osterloh A, Papp S, Moderzynski K, Kuehl S, Richardt U, Fleischer B. Persisting Rickettsia typhi Causes Fatal Central Nervous System Inflammation. Infect Immun. 2016;84:1615-1632 pubmed publisher
  • flow cytometry; mouse; fig s5
Catarinella M, Monestiroli A, Escobar G, Fiocchi A, Tran N, Aiolfi R, et al. IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment. EMBO Mol Med. 2016;8:155-70 pubmed publisher
  • flow cytometry; mouse
Guttman O, Yossef R, Freixo Lima G, Rider P, Porgador A, Lewis E. α1-Antitrypsin modifies general NK cell interactions with dendritic cells and specific interactions with islet β-cells in favor of protection from autoimmune diabetes. Immunology. 2014;: pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Janakiram N, Mohammed A, Bryant T, Brewer M, Biddick L, Lightfoot S, et al. Adoptive transfer of regulatory T cells promotes intestinal tumorigenesis and is associated with decreased NK cells and IL-22 binding protein. Mol Carcinog. 2015;54:986-98 pubmed publisher
Li T, Jiang S, Zhang Y, Luo J, Li M, Ke H, et al. Nanoparticle-mediated TRPV1 channel blockade amplifies cancer thermo-immunotherapy via heat shock factor 1 modulation. Nat Commun. 2023;14:2498 pubmed publisher
Hu J, S xe1 nchez Rivera F, Wang Z, Johnson G, Ho Y, Ganesh K, et al. STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma. Nature. 2023;616:806-813 pubmed publisher
Hattori K, Takagi H, Ogata Y, Yamada T, Horiba H, Fukata K, et al. Immunostimulatory effects of a subcritical water extract of Ganoderma. Biomed Rep. 2023;18:1 pubmed publisher
Dolgova E, Kirikovich S, Levites E, Ruzanova V, Proskurina A, Ritter G, et al. Analysis of the Biological Properties of Blood Plasma Protein with GcMAF Functional Activity. Int J Mol Sci. 2022;23: pubmed publisher
Cluff E, Magdaleno C, Fernandez E, House T, Swaminathan S, Varadaraj A, et al. Hypoxia-inducible factor-1 alpha expression is induced by IL-2 via the PI3K/mTOR pathway in hypoxic NK cells and supports effector functions in NKL cells and ex vivo expanded NK cells. Cancer Immunol Immunother. 2022;: pubmed publisher
Teng F, Tach xf3 Pi xf1 ot R, Sung B, Farber D, Worgall S, Hammad H, et al. ILC3s control airway inflammation by limiting T cell responses to allergens and microbes. Cell Rep. 2021;37:110051 pubmed publisher
Progatzky F, Shapiro M, Chng S, García Cassani B, Classon C, Sevgi S, et al. Regulation of intestinal immunity and tissue repair by enteric glia. Nature. 2021;599:125-130 pubmed publisher
Almeida A, Fein M, Egeblad M. Multi-color Flow Cytometry for Comprehensive Analysis of the Tumor Immune Infiltrate in a Murine Model of Breast Cancer. Bio Protoc. 2021;11:e4012 pubmed publisher
Sheppard S, Santosa E, Lau C, Violante S, Giovanelli P, Kim H, et al. Lactate dehydrogenase A-dependent aerobic glycolysis promotes natural killer cell anti-viral and anti-tumor function. Cell Rep. 2021;35:109210 pubmed publisher
Ye X, Wang X, Yu W, Yang Q, Li Y, Jin Y, et al. Synergistic effects of AAGL and anti-PD-1 on hepatocellular carcinoma through lymphocyte recruitment to the liver. Cancer Biol Med. 2021;: pubmed publisher
Guo S, Smeltz R, Nanajian A, Heller R. IL-15/IL-15Rα Heterodimeric Complex as Cancer Immunotherapy in Murine Breast Cancer Models. Front Immunol. 2020;11:614667 pubmed publisher
Wiedemann G, Grassmann S, Lau C, Rapp M, Villarino A, Friedrich C, et al. Divergent Role for STAT5 in the Adaptive Responses of Natural Killer Cells. Cell Rep. 2020;33:108498 pubmed publisher
Li J, Yuan S, Norgard R, Yan F, Sun Y, Kim I, et al. Epigenetic and transcriptional control of the epidermal growth factor receptor (EGFR) regulates the tumor immune microenvironment in pancreatic cancer. Cancer Discov. 2020;: pubmed publisher
Díaz Salazar C, Sun J. Coordinated Viral Control by Cytotoxic Lymphocytes Ensures Optimal Adaptive NK Cell Responses. Cell Rep. 2020;32:108186 pubmed publisher
Starkl P, Watzenboeck M, Popov L, Zahalka S, Hladik A, Lakovits K, et al. IgE Effector Mechanisms, in Concert with Mast Cells, Contribute to Acquired Host Defense against Staphylococcusaureus. Immunity. 2020;53:793-804.e9 pubmed publisher
Ruiz Manzano R, Palacios Arreola M, Hernández Cervantes R, Del Rio Araiza V, Nava Castro K, Ostoa Saloma P, et al. Potential Novel Risk Factor for Breast Cancer: Toxocara canis Infection Increases Tumor Size Due to Modulation of the Tumor Immune Microenvironment. Front Oncol. 2020;10:736 pubmed publisher
Schaffert A, Hanić M, Novokmet M, Zaytseva O, Krištić J, Lux A, et al. Minimal B Cell Extrinsic IgG Glycan Modifications of Pro- and Anti-Inflammatory IgG Preparations in vivo. Front Immunol. 2019;10:3024 pubmed publisher
Fu R, Guo H, Janga S, Choi M, Klinngam W, Edman M, et al. Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sjögren's syndrome murine model. Sci Rep. 2020;10:1455 pubmed publisher
Fachi J, Sécca C, Rodrigues P, Mato F, Di Luccia B, Felipe J, et al. Acetate coordinates neutrophil and ILC3 responses against C. difficile through FFAR2. J Exp Med. 2020;217: pubmed publisher
Li J, Yuan S, Norgard R, Yan F, Yamazoe T, Blanco A, et al. Tumor Cell-Intrinsic USP22 Suppresses Antitumor Immunity in Pancreatic Cancer. Cancer Immunol Res. 2020;8:282-291 pubmed publisher
Kang Y, Biswas A, Field M, Snapper S. STAT1 signaling shields T cells from NK cell-mediated cytotoxicity. Nat Commun. 2019;10:912 pubmed publisher
Geary C, Krishna C, Lau C, Adams N, Gearty S, Pritykin Y, et al. Non-redundant ISGF3 Components Promote NK Cell Survival in an Auto-regulatory Manner during Viral Infection. Cell Rep. 2018;24:1949-1957.e6 pubmed publisher
Adams N, Lau C, Fan X, Rapp M, Geary C, Weizman O, et al. Transcription Factor IRF8 Orchestrates the Adaptive Natural Killer Cell Response. Immunity. 2018;48:1172-1182.e6 pubmed publisher
Best S, De Souza D, Kersbergen A, Policheni A, Dayalan S, Tull D, et al. Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment. Cell Metab. 2018;27:935-943.e4 pubmed publisher
Fu B, Zhou Y, Ni X, Tong X, Xu X, Dong Z, et al. Natural Killer Cells Promote Fetal Development through the Secretion of Growth-Promoting Factors. Immunity. 2017;47:1100-1113.e6 pubmed publisher
Liu C, Min X, Wang N, Wang J, Ma N, Dong X, et al. Complement Receptor 3 Has Negative Impact on Tumor Surveillance through Suppression of Natural Killer Cell Function. Front Immunol. 2017;8:1602 pubmed publisher
Yuan X, Yang B, Dong Y, Yamamura A, Fu W. CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells. elife. 2017;6: pubmed publisher
Zhao L, Thorsheim C, Suzuki A, Stalker T, Min S, Lian L, et al. Phosphatidylinositol transfer protein-α in platelets is inconsequential for thrombosis yet is utilized for tumor metastasis. Nat Commun. 2017;8:1216 pubmed publisher
Palacios Arreola M, Nava Castro K, Río Araiza V, Pérez Sánchez N, Morales Montor J. A single neonatal administration of Bisphenol A induces higher tumour weight associated to changes in tumour microenvironment in the adulthood. Sci Rep. 2017;7:10573 pubmed publisher
Victorino F, Sojka D, Brodsky K, McNamee E, Masterson J, Homann D, et al. Tissue-Resident NK Cells Mediate Ischemic Kidney Injury and Are Not Depleted by Anti-Asialo-GM1 Antibody. J Immunol. 2015;195:4973-85 pubmed publisher
Li Y, Wang J, Gao S, Liu Q, Bai J, Zhao X, et al. Decreased peripheral natural killer cells activity in the immune activated stage of chronic hepatitis B. PLoS ONE. 2014;9:e86927 pubmed publisher
Vogt M, Dowd K, Engle M, Tesh R, Johnson S, Pierson T, et al. Poorly neutralizing cross-reactive antibodies against the fusion loop of West Nile virus envelope protein protect in vivo via Fcgamma receptor and complement-dependent effector mechanisms. J Virol. 2011;85:11567-80 pubmed publisher
Guerriero J, Ditsworth D, Catanzaro J, Sabino G, Furie M, Kew R, et al. DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity. J Immunol. 2011;186:3517-26 pubmed publisher
product information
Antigen :
CD335
Apps. Abbrev. :
FC
Cat # :
137604
Clone :
29A1.4
Item :
PE anti-mouse CD335 (NKp46)
Isotype :
Rat IgG2a, κ
Other Names :
NKp46, NCR1
Size :
100 μg
Price (USD) :
286 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PE
Immunogen :
NKP46-IgG1 Fc fusion protein
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of frozen tissue sections^1,2 and in vitro activation of NK cells^1.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA