product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-mouse/human Helios
catalog :
137204
quantity :
25 tests
price :
165 USD
clonality :
monoclonal
host :
hamsters
conjugate :
FITC
clone name :
22F6
reactivity :
human, mouse
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 26
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 3
Rissiek A, Baumann I, Cuapio A, Mautner A, Kolster M, Arck P, et al. The expression of CD39 on regulatory T cells is genetically driven and further upregulated at sites of inflammation. J Autoimmun. 2015;58:12-20 pubmed publisher
Zhang B, Sun J, Yuan Y, Ji D, Sun Y, Liu Y, et al. Proximity-enabled covalent binding of IL-2 to IL-2Rα selectively activates regulatory T cells and suppresses autoimmunity. Signal Transduct Target Ther. 2023;8:28 pubmed publisher
Luo Y, Xu C, Wang B, Niu Q, Su X, Bai Y, et al. Single-cell transcriptomic analysis reveals disparate effector differentiation pathways in human Treg compartment. Nat Commun. 2021;12:3913 pubmed publisher
Shi L, Sun Z, Su W, Xu F, Xie D, Zhang Q, et al. Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke. Immunity. 2021;54:1527-1542.e8 pubmed publisher
Andersen L, Gülich A, Alteneder M, Preglej T, Orola M, Dhele N, et al. The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells. Cell Rep. 2019;29:4447-4459.e6 pubmed publisher
Ickrath P, Scherzad A, Kleinsasser N, Ginzkey C, Hagen R, Hackenberg S. Influence of nasal polyp tissue on the differentiation and activation of T lymphocytes in a co-culture system. Biomed Rep. 2019;10:119-126 pubmed publisher
Britton G, Contijoch E, Mogno I, Vennaro O, Llewellyn S, Ng R, et al. Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt+ Regulatory T Cells and Exacerbate Colitis in Mice. Immunity. 2019;50:212-224.e4 pubmed publisher
Trotta E, Bessette P, Silveria S, Ely L, Jude K, Le D, et al. A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism. Nat Med. 2018;24:1005-1014 pubmed publisher
Halim T, Rana B, Walker J, Kerscher B, Knolle M, Jolin H, et al. Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells. Immunity. 2018;48:1195-1207.e6 pubmed publisher
Ickrath P, Kleinsasser N, Ding X, Ginzkey C, Beyersdorf N, Hagen R, et al. Accumulation of CD69+ tissue‑resident memory T cells in the nasal polyps of patients with chronic rhinosinusitis. Int J Mol Med. 2018;42:1116-1124 pubmed publisher
Toor S, Syed Khaja A, Alkurd I, Elkord E. In-vitro effect of pembrolizumab on different T regulatory cell subsets. Clin Exp Immunol. 2017;: pubmed publisher
Chachage M, Pollakis G, Kuffour E, Haase K, Bauer A, Nadai Y, et al. CD25+ FoxP3+ Memory CD4 T Cells Are Frequent Targets of HIV Infection In Vivo. J Virol. 2016;90:8954-67 pubmed publisher
Huijts C, Santegoets S, Quiles Del Rey M, de Haas R, Verheul H, de Gruijl T, et al. Differential effects of inhibitors of the PI3K/mTOR pathway on the expansion and functionality of regulatory T cells. Clin Immunol. 2016;168:47-54 pubmed publisher
Chowdhury A, Del Rio Estrada P, Del Rio P, Tharp G, Trible R, Amara R, et al. Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (TFH) in Simian Immunodeficiency Virus-Infected Rhesus Macaques May Contribute to Accumulation of TFH in Chronic Infection. J Immunol. 2015;195:3237-47 pubmed publisher
Huijts C, Schneiders F, Garcia Vallejo J, Verheul H, de Gruijl T, van der Vliet H. mTOR Inhibition Per Se Induces Nuclear Localization of FOXP3 and Conversion of Invariant NKT (iNKT) Cells into Immunosuppressive Regulatory iNKT Cells. J Immunol. 2015;195:2038-45 pubmed publisher
Litjens N, Boer K, Zuijderwijk J, Klepper M, Peeters A, Prens E, et al. Allogeneic Mature Human Dendritic Cells Generate Superior Alloreactive Regulatory T Cells in the Presence of IL-15. J Immunol. 2015;194:5282-93 pubmed publisher
Verhagen J, Wraith D. Blockade of LFA-1 augments in vitro differentiation of antigen-induced Foxp3? Treg cells. J Immunol Methods. 2014;414:58-64 pubmed publisher
Liu Y, Tran D, Fatheree N, Marc Rhoads J. Lactobacillus reuteri DSM 17938 differentially modulates effector memory T cells and Foxp3+ regulatory T cells in a mouse model of necrotizing enterocolitis. Am J Physiol Gastrointest Liver Physiol. 2014;307:G177-86 pubmed publisher
Bedke T, Iannitti R, De Luca A, Giovannini G, Fallarino F, Berges C, et al. Distinct and complementary roles for Aspergillus fumigatus-specific Tr1 and Foxp3+ regulatory T cells in humans and mice. Immunol Cell Biol. 2014;92:659-70 pubmed publisher
Angin M, Klarenbeek P, King M, Sharma S, Moodley E, Rezai A, et al. Regulatory T cells expanded from HIV-1-infected individuals maintain phenotype, TCR repertoire and suppressive capacity. PLoS ONE. 2014;9:e86920 pubmed publisher
Angin M, King M, Addo M. New tools to expand regulatory T cells from HIV-1-infected individuals. J Vis Exp. 2013;:e50244 pubmed publisher
Stone B, Rieck M, Rawlings C, Kas A, Shendure J, Jones H, et al. Identification of novel HLA class II target epitopes for generation of donor-specific T regulatory cells. Clin Immunol. 2012;145:153-60 pubmed publisher
Vaeth M, Schliesser U, Müller G, Reissig S, Satoh K, Tuettenberg A, et al. Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells. Proc Natl Acad Sci U S A. 2012;109:16258-63 pubmed publisher
Nakagome K, Imamura M, Kawahata K, Harada H, Okunishi K, Matsumoto T, et al. High expression of IL-22 suppresses antigen-induced immune responses and eosinophilic airway inflammation via an IL-10-associated mechanism. J Immunol. 2011;187:5077-89 pubmed publisher
Long S, Rieck M, Tatum M, Bollyky P, Wu R, Muller I, et al. Low-dose antigen promotes induction of FOXP3 in human CD4+ T cells. J Immunol. 2011;187:3511-20 pubmed publisher
Thornton A, Korty P, Tran D, Wohlfert E, Murray P, Belkaid Y, et al. Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. J Immunol. 2010;184:3433-41 pubmed publisher
product information
Antigen :
Helios
Apps. Abbrev. :
ICFC
Cat # :
137204
Clone :
22F6
Item :
FITC anti-mouse/human Helios
Isotype :
Armenian Hamster IgG
Other Names :
IKZF2, IKAROS family zinc finger 2, ANF1A2, ZNF1A2, ZNFN1A2
Size :
25 tests
Price (USD) :
165 USD
Reactivity :
Mouse, Human
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
FITC
Immunogen :
Helios peptide (aa 51-107)
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA