product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 488 anti-mouse CD68
catalog :
137011
quantity :
25 μg
price :
147 USD
clonality :
monoclonal
host :
rat
conjugate :
AF488
clone name :
FA-11
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 29
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:200; loading ...; fig 5e
Van De Velde L, Allen E, Crawford J, Wilson T, Guy C, Russier M, et al. Neuroblastoma Formation Requires Unconventional CD4 T Cells and Arginase-1-Dependent Myeloid Cells. Cancer Res. 2021;81:5047-5059 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 6a
Borges P, Waclawiak I, Georgii J, Fraga Junior V, Barros J, Lemos F, et al. Adenosine Diphosphate Improves Wound Healing in Diabetic Mice Through P2Y12 Receptor Activation. Front Immunol. 2021;12:651740 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1c
da Silva R, Elizondo D, Brandy N, Haddock N, Boddie T, de Oliveira L, et al. Leishmania donovani infection suppresses Allograft Inflammatory Factor-1 in monocytes and macrophages to inhibit inflammatory responses. Sci Rep. 2021;11:946 pubmed publisher
  • flow cytometry; mouse; 1:300; loading ...; fig 3e
BURNS J, Cotleur B, Walther D, Bajrami B, Rubino S, Wei R, et al. Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain. elife. 2020;9: pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig s2c
Norris G, Smirnov I, Filiano A, Shadowen H, Cody K, Thompson J, et al. Neuronal integrity and complement control synaptic material clearance by microglia after CNS injury. J Exp Med. 2018;215:1789-1801 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig ev1b
Gurevich D, Severn C, Twomey C, Greenhough A, Cash J, Toye A, et al. Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression. EMBO J. 2018;37: pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2a
Ni K, Gill A, Tseng V, Mikosz A, Koike K, Beatman E, et al. Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury. Respir Res. 2018;19:107 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2a
Chang S, Kohlgruber A, Mizoguchi F, Michelet X, Wolf B, Wei K, et al. Stromal cell cadherin-11 regulates adipose tissue inflammation and diabetes. J Clin Invest. 2017;127:3300-3312 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2h
Roufaiel M, Gracey E, Siu A, Zhu S, Lau A, Ibrahim H, et al. CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima. Nat Immunol. 2016;17:1263-1272 pubmed publisher
Basta M, Petruk S, Summer R, Rosenbloom J, Wermuth P, Macarak E, et al. Changes in nascent chromatin structure regulate activation of the pro-fibrotic transcriptome and myofibroblast emergence in organ fibrosis. iScience. 2023;26:106570 pubmed publisher
Fukuzaki Y, Faustino J, Lecuyer M, Rayasam A, Vexler Z. Global sphingosine-1-phosphate receptor 2 deficiency attenuates neuroinflammation and ischemic-reperfusion injury after neonatal stroke. iScience. 2023;26:106340 pubmed publisher
Mizutani T, Ano T, Yoshioka Y, Mizuta S, Takemoto K, Ouchi Y, et al. Neutrophil S100A9 supports M2 macrophage niche formation in granulomas. iScience. 2023;26:106081 pubmed publisher
Chen O, He Q, Han Q, Furutani K, Gu Y, Olexa M, et al. Mechanisms and treatments of neuropathic itch in a mouse model of lymphoma. J Clin Invest. 2023;133: pubmed publisher
Reitinger C, Ipsen Escobedo A, Hornung C, Heger L, Dudziak D, Lux A, et al. Modulation of urelumab glycosylation separates immune stimulatory activity from organ toxicity. Front Immunol. 2022;13:970290 pubmed publisher
Paterson N, Lämmermann T. Macrophage network dynamics depend on haptokinesis for optimal local surveillance. elife. 2022;11: pubmed publisher
Lv F, Liu H, Zhao G, Zhao E, Yan H, Che R, et al. Therapeutic exosomal vaccine for enhanced cancer immunotherapy by mediating tumor microenvironment. iScience. 2022;25:103639 pubmed publisher
DeDreu J, Pal Ghosh S, Mattapallil M, Caspi R, Stepp M, Menko A. Uveitis-mediated immune cell invasion through the extracellular matrix of the lens capsule. FASEB J. 2022;36:e21995 pubmed publisher
Tang P, Chung J, Xue V, Xiao J, Meng X, Huang X, et al. Smad3 Promotes Cancer-Associated Fibroblasts Generation via Macrophage-Myofibroblast Transition. Adv Sci (Weinh). 2022;9:e2101235 pubmed publisher
Sun Z, Xu D, Zhao L, Li X, Li S, Huang X, et al. A new therapeutic effect of fenofibrate in Duchenne muscular dystrophy: The promotion of myostatin degradation. Br J Pharmacol. 2022;179:1237-1250 pubmed publisher
Wang L, Ernst A, Flanders J, Liu W, Wang X, Datta A, et al. An inverse-breathing encapsulation system for cell delivery. Sci Adv. 2021;7: pubmed publisher
Zhou Y, Bennett T, Shiels A. Mutation of the TRPM3 cation channel underlies progressive cataract development and lens calcification associated with pro-fibrotic and immune cell responses. FASEB J. 2021;35:e21288 pubmed publisher
Li C, Xue V, Wang Q, Lian G, Huang X, Lee T, et al. The Mincle/Syk/NF-κB Signaling Circuit Is Essential for Maintaining the Protumoral Activities of Tumor-Associated Macrophages. Cancer Immunol Res. 2020;8:1004-1017 pubmed publisher
DeDreu J, Bowen C, Logan C, Pal Ghosh S, Parlanti P, Stepp M, et al. An immune response to the avascular lens following wounding of the cornea involves ciliary zonule fibrils. FASEB J. 2020;34:9316-9336 pubmed publisher
Zhou Y, Bennett T, Shiels A. A charged multivesicular body protein (CHMP4B) is required for lens growth and differentiation. Differentiation. 2019;109:16-27 pubmed publisher
Logan C, Bowen C, Menko A. Induction of Immune Surveillance of the Dysmorphogenic Lens. Sci Rep. 2017;7:16235 pubmed publisher
Barbour T, Ling G, Ruseva M, Fossati Jimack L, Cook H, Botto M, et al. Complement receptor 3 mediates renal protection in experimental C3 glomerulopathy. Kidney Int. 2016;89:823-32 pubmed publisher
Vegas A, Veiseh O, Doloff J, Ma M, Tam H, Bratlie K, et al. Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates. Nat Biotechnol. 2016;34:345-52 pubmed publisher
García L, Leimgruber C, Uribe Echevarría E, Acosta P, Brahamian J, Polack F, et al. Protective phenotypes of club cells and alveolar macrophages are favored as part of endotoxin-mediated prevention of asthma. Exp Biol Med (Maywood). 2015;240:904-16 pubmed publisher
Kawasaki N, VELA J, Nycholat C, Rademacher C, Khurana A, Van Rooijen N, et al. Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation. Proc Natl Acad Sci U S A. 2013;110:7826-31 pubmed publisher
product information
Antigen :
CD68
Apps. Abbrev. :
ICFC, FC, 3D IHC
Cat # :
137011
Clone :
FA-11
Item :
Alexa Fluor® 488 anti-mouse CD68
Isotype :
Rat IgG2a
Other Names :
Macrosialin
Size :
25 μg
Price (USD) :
147 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
A488
Immunogen :
Purified Con A receptor glycoproteins from the P815 cell line
Application Notes :
Additional reported (for relevant formats) applications include: immunoprecipitation^1, 2, Western Blot^1, 2, immunohistochemical staining of frozen sections^2 and paraformaldehyde-fixed paraffin-embedded sections^3, and spatial biology (IBEX)^9,10.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA