product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-mouse CD140a
catalog :
135907
quantity :
25 μg
price :
90 USD
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
APA5
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 60
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:100; fig s21
Wei Y, Sun H, Gui T, Yao L, Zhong L, Yu W, et al. The critical role of Hedgehog-responsive mesenchymal progenitors in meniscus development and injury repair. elife. 2021;10: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1c
Lu Z, Ortiz A, Verginadis I, Peck A, Zahedi F, Cho C, et al. Regulation of intercellular biomolecule transfer-driven tumor angiogenesis and responses to anticancer therapies. J Clin Invest. 2021;131: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4d
Chen J, Sivan U, Tan S, Lippo L, De Angelis J, Labella R, et al. High-resolution 3D imaging uncovers organ-specific vascular control of tissue aging. Sci Adv. 2021;7: pubmed publisher
  • flow cytometry; mouse; 1:100; fig s2l
Ohlund D, Handly Santana A, Biffi G, Elyada E, Almeida A, Ponz Sarvisé M, et al. Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer. J Exp Med. 2017;214:579-596 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig s5c
Nakaya M, Watari K, Tajima M, Nakaya T, Matsuda S, Ohara H, et al. Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction. J Clin Invest. 2017;127:383-401 pubmed publisher
  • flow cytometry; mouse; fig 2c
Tsukui T, Ueha S, Shichino S, Inagaki Y, Matsushima K. Intratracheal cell transfer demonstrates the profibrotic potential of resident fibroblasts in pulmonary fibrosis. Am J Pathol. 2015;185:2939-48 pubmed publisher
Akasaka H, Lee W, Ko S, Lengyel E, Naora H. Normal saline remodels the omentum and stimulates its receptivity for transcoelomic metastasis. JCI Insight. 2023;8: pubmed publisher
Sastourn xe9 Arrey Q, Mathieu M, Contreras X, Monferran S, Bourlier V, Gil Ortega M, et al. Adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injury. Nat Commun. 2023;14:80 pubmed publisher
Nawaz A, Bilal M, Fujisaka S, Kado T, Aslam M, Ahmed S, et al. Depletion of CD206+ M2-like macrophages induces fibro-adipogenic progenitors activation and muscle regeneration. Nat Commun. 2022;13:7058 pubmed publisher
Ko T, Nomura S, Yamada S, Fujita K, Fujita T, Satoh M, et al. Cardiac fibroblasts regulate the development of heart failure via Htra3-TGF-β-IGFBP7 axis. Nat Commun. 2022;13:3275 pubmed publisher
Korsunsky I, Wei K, Pohin M, Kim E, Barone F, Major T, et al. Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases. Med. 2022;3:481-518.e14 pubmed publisher
Agarwalla P, Ogunnaike E, Ahn S, Froehlich K, Jansson A, Ligler F, et al. Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells. Nat Biotechnol. 2022;: pubmed publisher
Shi X, Chen Y, Liu Q, Mei X, Liu J, Tang Y, et al. LDLR dysfunction induces LDL accumulation and promotes pulmonary fibrosis. Clin Transl Med. 2022;12:e711 pubmed publisher
Hattori Y, Itoh H, Tsugawa Y, Nishida Y, Kurata K, Uemura A, et al. Embryonic Pericytes Promote Microglial Homeostasis and Their Effects on Neural Progenitors in the Developing Cerebral Cortex. J Neurosci. 2022;42:362-376 pubmed publisher
Chen Y, Yang Q, Hu Y, Liu X, de Avila J, Zhu M, et al. Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance. Nat Commun. 2021;12:6845 pubmed publisher
Progatzky F, Shapiro M, Chng S, García Cassani B, Classon C, Sevgi S, et al. Regulation of intestinal immunity and tissue repair by enteric glia. Nature. 2021;599:125-130 pubmed publisher
Kinsella S, Evandy C, Cooper K, Iovino L, deRoos P, Hopwo K, et al. Attenuation of apoptotic cell detection triggers thymic regeneration after damage. Cell Rep. 2021;37:109789 pubmed publisher
Ghelman J, Grewing L, Windener F, Albrecht S, Zarbock A, Kuhlmann T. SKAP2 as a new regulator of oligodendroglial migration and myelin sheath formation. Glia. 2021;: pubmed publisher
Vazquez Armendariz A, Seeger W, Herold S, El Agha E. Protocol for the generation of murine bronchiolospheres. STAR Protoc. 2021;2:100594 pubmed publisher
Gui J, Zahedi F, Ortiz A, Cho C, Katlinski K, Alicea Torres K, et al. Activation of p38α stress-activated protein kinase drives the formation of the pre-metastatic niche in the lungs. Nat Cancer. 2020;1:603-619 pubmed publisher
Hu Y, Li X, Zhi X, Cong W, Huang B, Chen H, et al. RANKL from bone marrow adipose lineage cells promotes osteoclast formation and bone loss. EMBO Rep. 2021;22:e52481 pubmed publisher
Kastenschmidt J, Coulis G, Farahat P, Pham P, Rios R, Cristal T, et al. A stromal progenitor and ILC2 niche promotes muscle eosinophilia and fibrosis-associated gene expression. Cell Rep. 2021;35:108997 pubmed publisher
Mohrin M, Liu J, Zavala Solorio J, Bhargava S, Maxwell Trumble J, Brito A, et al. Inhibition of longevity regulator PAPP-A modulates tissue homeostasis via restraint of mesenchymal stromal cells. Aging Cell. 2021;20:e13313 pubmed publisher
Moiseenko A, Vazquez Armendariz A, Kheirollahi V, Chu X, Tata A, Rivetti S, et al. Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration. Cell Rep. 2020;33:108549 pubmed publisher
Paris A, Hayer K, Oved J, Avgousti D, Toulmin S, Zepp J, et al. STAT3-BDNF-TrkB signalling promotes alveolar epithelial regeneration after lung injury. Nat Cell Biol. 2020;22:1197-1210 pubmed publisher
Reddy A, Bozi L, Yaghi O, Mills E, Xiao H, Nicholson H, et al. pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise. Cell. 2020;183:62-75.e17 pubmed publisher
Jardé T, Chan W, Rossello F, Kaur Kahlon T, Theocharous M, Kurian Arackal T, et al. Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium. Cell Stem Cell. 2020;27:646-662.e7 pubmed publisher
Oguri Y, Shinoda K, Kim H, Alba D, Bolus W, Wang Q, et al. CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling. Cell. 2020;: pubmed publisher
Wong P, Muñoz Félix J, Hijazi M, Kim H, Robinson S, de Luxán Delgado B, et al. Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells. Cell. 2020;181:1346-1363.e21 pubmed publisher
WIETECHA M, Pensalfini M, Cangkrama M, Muller B, Jin J, Brinckmann J, et al. Activin-mediated alterations of the fibroblast transcriptome and matrisome control the biomechanical properties of skin wounds. Nat Commun. 2020;11:2604 pubmed publisher
Grainger N, Freeman R, Shonnard C, Drumm B, Koh S, Ward S, et al. Identification and classification of interstitial cells in the mouse renal pelvis. J Physiol. 2020;598:3283-3307 pubmed publisher
Bahar Halpern K, Massalha H, Zwick R, Moor A, Castillo Azofeifa D, Rozenberg M, et al. Lgr5+ telocytes are a signaling source at the intestinal villus tip. Nat Commun. 2020;11:1936 pubmed publisher
Shook B, Wasko R, Mano O, Rutenberg Schoenberg M, Rudolph M, Zirak B, et al. Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair. Cell Stem Cell. 2020;26:880-895.e6 pubmed publisher
Jing Y, Chávez V, Khatwani N, Ban Y, Espejo A, Chen X, et al. In vivo antitumor activity by dual stromal and tumor-targeted oncolytic measles viruses. Cancer Gene Ther. 2020;27:910-922 pubmed publisher
Cangkrama M, Wietecha M, Mathis N, Okumura R, Ferrarese L, Al Nuaimi D, et al. A paracrine activin A-mDia2 axis promotes squamous carcinogenesis via fibroblast reprogramming. EMBO Mol Med. 2020;12:e11466 pubmed publisher
Vasanthakumar A, Chisanga D, Blume J, Gloury R, Britt K, Henstridge D, et al. Sex-specific adipose tissue imprinting of regulatory T cells. Nature. 2020;579:581-585 pubmed publisher
Zhang X, Wang X, Yin H, Zhang L, Feng A, Zhang Q, et al. Functional Inactivation of Mast Cells Enhances Subcutaneous Adipose Tissue Browning in Mice. Cell Rep. 2019;28:792-803.e4 pubmed publisher
Hogarth M, Defour A, LAZARSKI C, Gallardo E, Diaz Manera J, Partridge T, et al. Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B. Nat Commun. 2019;10:2430 pubmed publisher
Wang W, Ishibashi J, Trefely S, Shao M, Cowan A, Sakers A, et al. A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate. Cell Metab. 2019;: pubmed publisher
Nowlan B, Williams E, Doran M, Levesque J. CD27, CD201, FLT3, CD48, and CD150 cell surface staining identifies long-term mouse hematopoietic stem cells in immunodeficient non-obese diabetic severe combined immune deficient derived strains. Haematologica. 2019;: pubmed publisher
Srivastava S, Salter A, Liggitt D, Yechan Gunja S, Sarvothama M, Cooper K, et al. Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting. Cancer Cell. 2019;35:489-503.e8 pubmed publisher
Dahlgren M, Jones S, Cautivo K, Dubinin A, Ortiz Carpena J, Farhat S, et al. Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches. Immunity. 2019;50:707-722.e6 pubmed publisher
Murakami Y, Naganuma H, Tanigawa S, Fujimori T, Eto M, Nishinakamura R. Reconstitution of the embryonic kidney identifies a donor cell contribution to the renal vasculature upon transplantation. Sci Rep. 2019;9:1172 pubmed publisher
Avraham S, Korin B, Aviram S, Shechter D, Shaked Y, Aronheim A. ATF3 and JDP2 deficiency in cancer associated fibroblasts promotes tumor growth via SDF-1 transcription. Oncogene. 2019;38:3812-3823 pubmed publisher
Pinho A, Van Bulck M, Chantrill L, Arshi M, Sklyarova T, Herrmann D, et al. ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling. Nat Commun. 2018;9:5083 pubmed publisher
Hepler C, Shan B, Zhang Q, Henry G, Shao M, Vishvanath L, et al. Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice. elife. 2018;7: pubmed publisher
Hiebert P, WIETECHA M, Cangkrama M, Haertel E, Mavrogonatou E, Stumpe M, et al. Nrf2-Mediated Fibroblast Reprogramming Drives Cellular Senescence by Targeting the Matrisome. Dev Cell. 2018;46:145-161.e10 pubmed publisher
Zhao T, Fu Y, Zhu J, Liu Y, Zhang Q, Yi Z, et al. Single-Cell RNA-Seq Reveals Dynamic Early Embryonic-like Programs during Chemical Reprogramming. Cell Stem Cell. 2018;23:31-45.e7 pubmed publisher
Wang Q, Song A, Chen W, Schwalie P, Zhang F, Vishvanath L, et al. Reversible De-differentiation of Mature White Adipocytes into Preadipocyte-like Precursors during Lactation. Cell Metab. 2018;28:282-288.e3 pubmed publisher
Taguchi A, Nishinakamura R. Higher-Order Kidney Organogenesis from Pluripotent Stem Cells. Cell Stem Cell. 2017;21:730-746.e6 pubmed publisher
Wang B, Fu X, Liang X, Deavila J, Wang Z, Zhao L, et al. Retinoic acid induces white adipose tissue browning by increasing adipose vascularity and inducing beige adipogenesis of PDGFRα+ adipose progenitors. Cell Discov. 2017;3:17036 pubmed publisher
Jadhav U, Saxena M, O Neill N, Saadatpour A, Yuan G, Herbert Z, et al. Dynamic Reorganization of Chromatin Accessibility Signatures during Dedifferentiation of Secretory Precursors into Lgr5+ Intestinal Stem Cells. Cell Stem Cell. 2017;21:65-77.e5 pubmed publisher
Schneider R, Mullally A, Dugourd A, Peisker F, Hoogenboezem R, van Strien P, et al. Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target. Cell Stem Cell. 2017;20:785-800.e8 pubmed publisher
Hulsmans M, Clauss S, Xiao L, Aguirre A, King K, Hanley A, et al. Macrophages Facilitate Electrical Conduction in the Heart. Cell. 2017;169:510-522.e20 pubmed publisher
Kurowska Stolarska M, Hasoo M, Welsh D, Stewart L, McIntyre D, Morton B, et al. The role of microRNA-155/liver X receptor pathway in experimental and idiopathic pulmonary fibrosis. J Allergy Clin Immunol. 2017;139:1946-1956 pubmed publisher
Corna G, Caserta I, Monno A, Apostoli P, Manfredi A, Camaschella C, et al. The Repair of Skeletal Muscle Requires Iron Recycling through Macrophage Ferroportin. J Immunol. 2016;197:1914-25 pubmed publisher
Chandrakanthan V, Yeola A, Kwan J, Oliver R, Qiao Q, Kang Y, et al. PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells. Proc Natl Acad Sci U S A. 2016;113:E2306-15 pubmed publisher
Singhal P, Sassi S, Lan L, Au P, Halvorsen S, Fukumura D, et al. Mouse embryonic fibroblasts exhibit extensive developmental and phenotypic diversity. Proc Natl Acad Sci U S A. 2016;113:122-7 pubmed publisher
Chen H, Goodus M, De Toledo S, Azzam E, Levison S, Souayah N. Ionizing Radiation Perturbs Cell Cycle Progression of Neural Precursors in the Subventricular Zone Without Affecting Their Long-Term Self-Renewal. ASN Neuro. 2015;7: pubmed publisher
Wang W, Kissig M, Rajakumari S, Huang L, Lim H, Won K, et al. Ebf2 is a selective marker of brown and beige adipogenic precursor cells. Proc Natl Acad Sci U S A. 2014;111:14466-71 pubmed publisher
product information
Antigen :
CD140a
Apps. Abbrev. :
FC
Cat # :
135907
Clone :
APA5
Item :
APC anti-mouse CD140a
Isotype :
Rat IgG2a, κ
Other Names :
PDGF receptor-α, PDGFR-α
Size :
25 μg
Price (USD) :
90 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
APC
Immunogen :
Mouse PDGFR-α-hIgG1 recombinant fusion protein
Application Notes :
Additional reported (for relevant formats) applications include: Western Blot, blocking function^2, and immunohistochemical staining of paraffin and frozen sections. The LEAF™ purified antibody is recommended for functional assays.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA