product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse CD140a
catalog :
135906
quantity :
200 μg
price :
426 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
APA5
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 56
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 5g
Chen M, Lu P, Ma Q, Cao Y, Chen N, Li W, et al. CTNNB1/β-catenin dysfunction contributes to adiposity by regulating the cross-talk of mature adipocytes and preadipocytes. Sci Adv. 2020;6:eaax9605 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4d
Thomson C, van de Pavert S, Stakenborg M, Labeeuw E, Matteoli G, Mowat A, et al. Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators. J Immunol. 2018;201:215-229 pubmed publisher
He T, Wang S, Li S, Shen H, Hou L, Liu Y, et al. Suppression of preadipocyte determination by SOX4 limits white adipocyte hyperplasia in obesity. iScience. 2023;26:106289 pubmed publisher
Contreras O, Harvey R. Single-cell transcriptome dynamics of the autotaxin-lysophosphatidic acid axis during muscle regeneration reveal proliferative effects in mesenchymal fibro-adipogenic progenitors. Front Cell Dev Biol. 2023;11:1017660 pubmed publisher
Kim D, Jeong J, Lee D, Hyeon D, Park G, Jeon S, et al. PD-L1-directed PlGF/VEGF blockade synergizes with chemotherapy by targeting CD141+ cancer-associated fibroblasts in pancreatic cancer. Nat Commun. 2022;13:6292 pubmed publisher
Poh A, O Brien M, Chisanga D, He H, Baloyan D, Traichel J, et al. Inhibition of HCK in myeloid cells restricts pancreatic tumor growth and metastasis. Cell Rep. 2022;41:111479 pubmed publisher
Rai S, Grockowiak E, Hansen N, Luque Paz D, Stoll C, Hao Shen H, et al. Inhibition of interleukin-1β reduces myelofibrosis and osteosclerosis in mice with JAK2-V617F driven myeloproliferative neoplasm. Nat Commun. 2022;13:5346 pubmed publisher
Fung C, Zhou S, Zhu H, Wei X, Wu Z, Wu A. Cell fate determining molecular switches and signaling pathways in Pax7-expressing somitic mesoderm. Cell Discov. 2022;8:61 pubmed publisher
Konishi S, Tata A, Tata P. Defined conditions for long-term expansion of murine and human alveolar epithelial stem cells in three-dimensional cultures. STAR Protoc. 2022;3:101447 pubmed publisher
Malolina E, Galiakberova A, Dashinimaev E, Kulibin A. Establishment of a pure culture of immature Sertoli cells by PDGFRA staining and cell sorting. Mol Reprod Dev. 2022;89:243-255 pubmed publisher
Velloso F, Kumari E, Buono K, Frondelli M, Levison S. Analyzing mouse neural stem cell and progenitor cell proliferation using EdU incorporation and multicolor flow cytometry. STAR Protoc. 2022;3:101065 pubmed publisher
Frondelli M, Mather M, Levison S. Oligodendrocyte progenitor proliferation is disinhibited following traumatic brain injury in leukemia inhibitory factor heterozygous mice. J Neurosci Res. 2022;100:578-597 pubmed publisher
Frech S, Forsthuber A, Korosec A, Lipp K, Kozumov V, Lichtenberger B. Hedgehog Signaling in Papillary Fibroblasts Is Essential for Hair Follicle Regeneration during Wound Healing. J Invest Dermatol. 2021;: pubmed publisher
Jakob L, M xfc ller T, Rassner M, Kleinfelder H, Veratti P, Mitschke J, et al. Murine Oncostatin M Has Opposing Effects on the Proliferation of OP9 Bone Marrow Stromal Cells and NIH/3T3 Fibroblasts Signaling through the OSMR. Int J Mol Sci. 2021;22: pubmed publisher
Frondelli M, Levison S. Leukemia Inhibitory Factor Is Required for Subventricular Zone Astrocyte Progenitor Proliferation and for Prokineticin-2 Production after a Closed Head Injury in Mice. Neurotrauma Rep. 2021;2:285-302 pubmed publisher
Hara T, Chanoch Myers R, Mathewson N, Myskiw C, Atta L, Bussema L, et al. Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma. Cancer Cell. 2021;39:779-792.e11 pubmed publisher
Buechler M, Pradhan R, Krishnamurty A, Cox C, Calviello A, Wang A, et al. Cross-tissue organization of the fibroblast lineage. Nature. 2021;593:575-579 pubmed publisher
Zelic M, Pontarelli F, Woodworth L, Zhu C, Mahan A, Ren Y, et al. RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis. Cell Rep. 2021;35:109112 pubmed publisher
Vercauteren Drubbel A, Pirard S, Kin S, Dassy B, Lefort A, Libert F, et al. Reactivation of the Hedgehog pathway in esophageal progenitors turns on an embryonic-like program to initiate columnar metaplasia. Cell Stem Cell. 2021;28:1411-1427.e7 pubmed publisher
Bravo J, Kim M, Benayoun B. Protocol for isolation of adult mouse ear pinnae-derived primary fibroblasts. STAR Protoc. 2021;2:100406 pubmed publisher
Xi W, Chen W, Sun W, Li X, Suo Z, Jiang G, et al. Mitochondrial activity regulates the differentiation of skin-derived mesenchymal stem cells into brown adipocytes to contribute to hypertension. Stem Cell Res Ther. 2021;12:167 pubmed publisher
Chen Y, Kim J, Yang S, Wang H, Wu C, Sugimoto H, et al. Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer. Cancer Cell. 2021;39:548-565.e6 pubmed publisher
Steele N, Biffi G, Kemp S, Zhang Y, Drouillard D, Syu L, et al. Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer. Clin Cancer Res. 2021;: pubmed publisher
Maller O, Drain A, Barrett A, Borgquist S, Ruffell B, Zakharevich I, et al. Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression. Nat Mater. 2021;20:548-559 pubmed publisher
Gabitova Cornell L, Surumbayeva A, Peri S, Franco Barraza J, Restifo D, Weitz N, et al. Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer. Cancer Cell. 2020;38:567-583.e11 pubmed publisher
Liu J, Li P, Wang L, Li M, Ge Z, Noordam L, et al. Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance. Cell Mol Gastroenterol Hepatol. 2021;11:407-431 pubmed publisher
Hasegawa T, Kikuta J, Sudo T, Yamashita E, Seno S, Takeuchi T, et al. Development of an intravital imaging system for the synovial tissue reveals the dynamics of CTLA-4 Ig in vivo. Sci Rep. 2020;10:13480 pubmed publisher
Runyan C, Welch L, Lecuona E, Shigemura M, Amarelle L, Abdala Valencia H, et al. Impaired phagocytic function in CX3CR1+ tissue-resident skeletal muscle macrophages prevents muscle recovery after influenza A virus-induced pneumonia in old mice. Aging Cell. 2020;: pubmed publisher
Velletri T, Huang Y, Wang Y, Li Q, Hu M, Xie N, et al. Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin. Cell Death Differ. 2021;28:156-169 pubmed publisher
Oguri Y, Shinoda K, Kim H, Alba D, Bolus W, Wang Q, et al. CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling. Cell. 2020;: pubmed publisher
Wang Y, Wang H, Guo J, Gao J, Wang M, Xia M, et al. LGR4, Not LGR5, Enhances hPSC Hematopoiesis by Facilitating Mesoderm Induction via TGF-Beta Signaling Activation. Cell Rep. 2020;31:107600 pubmed publisher
Lu A, Guo P, Wang L, Tseng C, Huard M, Allen C, et al. Heterogenetic parabiosis between healthy and dystrophic mice improve the histopathology in muscular dystrophy. Sci Rep. 2020;10:7075 pubmed publisher
Jackson Jones L, Smith P, Portman J, Magalhaes M, Mylonas K, Vermeren M, et al. Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants. Immunity. 2020;52:700-715.e6 pubmed publisher
Cardot Ruffino V, Chauvet V, Caligaris C, Bertrand Chapel A, Chuvin N, Pommier R, et al. Generation of an Fsp1 (fibroblast-specific protein 1)-Flpo transgenic mouse strain. Genesis. 2020;58:e23359 pubmed publisher
Cardot Ruffino V, Chauvet V, Caligaris C, Bertrand Chapel A, Chuvin N, Pommier R, et al. Generation of a conditional Flpo/FRT mouse model expressing constitutively active TGFβ in fibroblasts. Sci Rep. 2020;10:3880 pubmed publisher
Derecka M, Herman J, Cauchy P, Ramamoorthy S, Lupar E, Grün D, et al. EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential. Nat Immunol. 2020;21:261-273 pubmed publisher
Haider N, Larose L. Activation of the PDGFRα-Nrf2 pathway mediates impaired adipocyte differentiation in bone marrow mesenchymal stem cells lacking Nck1. Cell Commun Signal. 2020;18:26 pubmed publisher
Wu R, Liu C, Deng X, Chen L, Hao S, Ma L. Enhanced alleviation of aGVHD by TGF-β1-modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells. J Cell Mol Med. 2020;24:1684-1699 pubmed publisher
Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, et al. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. Nature. 2019;574:553-558 pubmed publisher
Buffolo M, Pires K, Ferhat M, Ilkun O, Makaju A, Achenbach A, et al. Identification of a Paracrine Signaling Mechanism Linking CD34high Progenitors to the Regulation of Visceral Fat Expansion and Remodeling. Cell Rep. 2019;29:270-282.e5 pubmed publisher
Shibamoto M, Higo T, Naito A, Nakagawa A, Sumida T, Okada K, et al. Activation of DNA Damage Response and Cellular Senescence in Cardiac Fibroblasts Limit Cardiac Fibrosis After Myocardial Infarction. Int Heart J. 2019;60:944-957 pubmed publisher
Buechler M, Kim K, Onufer E, Williams J, Little C, Dominguez C, et al. A Stromal Niche Defined by Expression of the Transcription Factor WT1 Mediates Programming and Homeostasis of Cavity-Resident Macrophages. Immunity. 2019;: pubmed publisher
Joshi P, Waterhouse P, Kasaian K, Fang H, Gulyaeva O, Sul H, et al. PDGFRα+ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland. Nat Commun. 2019;10:1760 pubmed publisher
Diekmann U, Wolling H, Dettmer R, Niwolik I, Naujok O, Buettner F. Chemically defined and xenogeneic-free differentiation of human pluripotent stem cells into definitive endoderm in 3D culture. Sci Rep. 2019;9:996 pubmed publisher
Ferrari N, Ranftl R, Chicherova I, Slaven N, Moeendarbary E, Farrugia A, et al. Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associated fibroblasts. Nat Commun. 2019;10:130 pubmed publisher
Stoupa A, Adam F, Kariyawasam D, Strassel C, Gawade S, Szinnai G, et al. TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology. EMBO Mol Med. 2018;10: pubmed publisher
Salzer M, Lafzi A, Berenguer Llergo A, Youssif C, Castellanos A, Solanas G, et al. Identity Noise and Adipogenic Traits Characterize Dermal Fibroblast Aging. Cell. 2018;: pubmed publisher
Biffi G, Oni T, Spielman B, Hao Y, Elyada E, Park Y, et al. IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma. Cancer Discov. 2019;9:282-301 pubmed publisher
Nawaz A, Mehmood A, Kanatani Y, Kado T, Igarashi Y, Takikawa A, et al. Sirt1 activator induces proangiogenic genes in preadipocytes to rescue insulin resistance in diet-induced obese mice. Sci Rep. 2018;8:11370 pubmed publisher
Burl R, Ramseyer V, Rondini E, Pique Regi R, Lee Y, Granneman J. Deconstructing Adipogenesis Induced by β3-Adrenergic Receptor Activation with Single-Cell Expression Profiling. Cell Metab. 2018;28:300-309.e4 pubmed publisher
Huang Z, Zhong L, Lee J, Zhang J, Wu D, Geng L, et al. The FGF21-CCL11 Axis Mediates Beiging of White Adipose Tissues by Coupling Sympathetic Nervous System to Type 2 Immunity. Cell Metab. 2017;26:493-508.e4 pubmed publisher
Wagner G, Lindroos Christensen J, Einwallner E, Husa J, Zapf T, Lipp K, et al. HO-1 inhibits preadipocyte proliferation and differentiation at the onset of obesity via ROS dependent activation of Akt2. Sci Rep. 2017;7:40881 pubmed publisher
Kwon H, Kim S, Kim Y, Lee Y. The contribution of arachidonate 15-lipoxygenase in tissue macrophages to adipose tissue remodeling. Cell Death Dis. 2016;7:e2285 pubmed publisher
Singhal P, Sassi S, Lan L, Au P, Halvorsen S, Fukumura D, et al. Mouse embryonic fibroblasts exhibit extensive developmental and phenotypic diversity. Proc Natl Acad Sci U S A. 2016;113:122-7 pubmed publisher
Chen H, Goodus M, De Toledo S, Azzam E, Levison S, Souayah N. Ionizing Radiation Perturbs Cell Cycle Progression of Neural Precursors in the Subventricular Zone Without Affecting Their Long-Term Self-Renewal. ASN Neuro. 2015;7: pubmed publisher
Ito K, Yamazaki S, Yamamoto R, Tajima Y, Yanagida A, Kobayashi T, et al. Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice. J Biol Chem. 2014;289:29892-911 pubmed publisher
product information
Antigen :
CD140a
Apps. Abbrev. :
FC
Cat # :
135906
Clone :
APA5
Item :
PE anti-mouse CD140a
Isotype :
Rat IgG2a, κ
Other Names :
PDGF receptor-α, PDGFR-α
Size :
200 μg
Price (USD) :
426 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PE
Immunogen :
Mouse PDGFR-α-hIgG1 recombinant fusion protein
Application Notes :
Additional reported (for relevant formats) applications include: Western Blot, blocking function^2, and immunohistochemical staining of paraffin and frozen sections. The LEAF™ purified antibody is recommended for functional assays.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA