product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse CD88 (C5aR)
catalog :
135805
quantity :
50 μg
price :
146 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
20/70
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 18
Reference
Monteran L, Ershaid N, Doron H, Zait Y, Scharff Y, Ben Yosef S, et al. Chemotherapy-induced complement signaling modulates immunosuppression and metastatic relapse in breast cancer. Nat Commun. 2022;13:5797 pubmed publisher
Purvis G, Aranda Tavío H, Channon K, Greaves D. Bruton's TK regulates myeloid cell recruitment during acute inflammation. Br J Pharmacol. 2022;179:2754-2770 pubmed publisher
Izumi G, Nakano H, Nakano K, Whitehead G, Grimm S, Fessler M, et al. CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation. Nat Commun. 2021;12:5029 pubmed publisher
Kim S, Cho B, Kim K, Jang Y. Complement C5a promotes antigen cross-presentation by Peyer's patch monocyte-derived dendritic cells and drives a protective CD8+ T cell response. Cell Rep. 2021;35:108995 pubmed publisher
Leach S, Gibbings S, Tewari A, Atif S, Vestal B, Danhorn T, et al. Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes. Cell Rep. 2020;33:108337 pubmed publisher
Neupane A, Willson M, Chojnacki A, Vargas E Silva Castanheira F, Morehouse C, Carestia A, et al. Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis. Cell. 2020;183:110-125.e11 pubmed publisher
Zheng Q, Xu F, Yang Y, Sun D, Zhong Y, Wu S, et al. C5a/C5aR1 mediates IMQ-induced psoriasiform skin inflammation by promoting IL-17A production from γδ-T cells. FASEB J. 2020;34:10590-10604 pubmed publisher
Bosteels C, Neyt K, Vanheerswynghels M, Van Helden M, Sichien D, Debeuf N, et al. Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection. Immunity. 2020;52:1039-1056.e9 pubmed publisher
Hoogendijk A, Pourfarzad F, Aarts C, Tool A, Hiemstra I, Grassi L, et al. Dynamic Transcriptome-Proteome Correlation Networks Reveal Human Myeloid Differentiation and Neutrophil-Specific Programming. Cell Rep. 2019;29:2505-2519.e4 pubmed publisher
Zheng Q, Liang S, Xu F, Li G, Luo N, Wu S, et al. C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis. Front Immunol. 2019;10:1866 pubmed publisher
Deniset J, Belke D, Lee W, Jorch S, Deppermann C, Hassanabad A, et al. Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis. Immunity. 2019;51:131-140.e5 pubmed publisher
Medler T, Murugan D, Horton W, Kumar S, Cotechini T, Forsyth A, et al. Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy. Cancer Cell. 2018;34:561-578.e6 pubmed publisher
Giles D, Duncker P, Wilkinson N, Washnock Schmid J, Segal B. CNS-resident classical DCs play a critical role in CNS autoimmune disease. J Clin Invest. 2018;128:5322-5334 pubmed publisher
Taylor L, Brodermann M, McCaffary D, Iqbal A, Greaves D. Netrin-1 Reduces Monocyte and Macrophage Chemotaxis towards the Complement Component C5a. PLoS ONE. 2016;11:e0160685 pubmed publisher
Mehta G, Scheinman R, Holers V, Banda N. A New Approach for the Treatment of Arthritis in Mice with a Novel Conjugate of an Anti-C5aR1 Antibody and C5 Small Interfering RNA. J Immunol. 2015;194:5446-54 pubmed publisher
Bisht K, Wegiel B, Tampe J, Neubauer O, Wagner K, Otterbein L, et al. Biliverdin modulates the expression of C5aR in response to endotoxin in part via mTOR signaling. Biochem Biophys Res Commun. 2014;449:94-9 pubmed publisher
Kim S, Jung D, Yang I, Jang S, Kim J, Truong T, et al. Application of an M-cell-targeting ligand for oral vaccination induces efficient systemic and mucosal immune responses against a viral antigen. Int Immunol. 2013;25:623-32 pubmed publisher
Bosmann M, Haggadone M, Hemmila M, Zetoune F, Sarma J, Ward P. Complement activation product C5a is a selective suppressor of TLR4-induced, but not TLR3-induced, production of IL-27(p28) from macrophages. J Immunol. 2012;188:5086-93 pubmed publisher
product information
Antigen :
CD88
Apps. Abbrev. :
FC
Cat # :
135805
Clone :
20/70
Item :
PE anti-mouse CD88 (C5aR)
Isotype :
Rat IgG2b, κ
Other Names :
C5a ligand, C5a anaphylatoxin receptor, C5AR, C5R1, C5AR1
Size :
50 μg
Price (USD) :
146 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PE
Immunogen :
mC5aR transfected cells
Application Notes :
Additional reported applications for the relevant formats include: blocking of C5a binding.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA